Group I metabotropic glutamate receptors reduce excitotoxic injury and may facilitate neurogenesis

Neurogenesis in the adult human hippocampus

1998 • 6,181 citations

A simple method for organotypic cultures of nervous tissue

1991 • 3,075 citations

Chronic Antidepressant Treatment Increases Neurogenesis in Adult Rat Hippocampus

2000 • 3,047 citations

Dentate Granule Cell Neurogenesis Is Increased by Seizures and Contributes to Aberrant Network Reorganization in the Adult Rat Hippocampus

1997 • 1,880 citations

Regulation of Phosphoinositide-Specific Phospholipase C

2001 • 1,604 citations

Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus

2001 • 1,554 citations

Neurogenesis in the Dentate Gyrus of the Adult Tree Shrew Is Regulated by Psychosocial Stress and NMDA Receptor Activation

1997 • 1,468 citations

Neurogenesis in Adult Subventricular Zone

2002 • 1,415 citations

Epidermal Growth Factor and Fibroblast Growth Factor-2 Have Different Effects on Neural Progenitors in the Adult Rat Brain

1997 • 1,206 citations

Structure, Function, and Control of Phosphoinositide-Specific Phospholipase C

2000 • 986 citations

Stereological methods for estimating the total number of neurons and synapses: issues of precision and bias

1999 • 842 citations

Peripheral Infusion of IGF-I Selectively Induces Neurogenesis in the Adult Rat Hippocampus

2000 • 838 citations

Multipotent progenitor cells in the adult dentate gyrus

1998 • 722 citations

Internalization of ionotropic glutamate receptors in response to mGluR activation

2001 • 540 citations

Progenitor cells from human brain after death

2001 • 460 citations

Insulin-Like Growth Factor-I Promotes Neurogenesis and Synaptogenesis in the Hippocampal Dentate Gyrus during Postnatal Development

2000 • 341 citations

Neurogenesis persists in the subependymal layer of the adult mouse brain

1993 • 262 citations

TOAD-64, a gene expressed early in neuronal differentiation in the rat, is related to unc-33, a C. elegans gene involved in axon outgrowth

1995 • 261 citations

Increased dentate granule cell neurogenesis following amygdala kindling in the adult rat

1998 • 261 citations

NMDA receptor antagonist treatment induces a long‐lasting increase in the number of proliferating cells, PSA‐NCAM‐immunoreactive granule neurons and radial glia in the adult rat dentate gyrus

2001 • 203 citations

A family of proteins implicated in axon guidance and outgrowth

1999 • 203 citations

Metabotropic glutamate receptor activation causes a rapid redistribution of AMPA receptors

2001 • 172 citations

Group-I metabotropic glutamate receptors: hypotheses to explain their dual role in neurotoxicity and neuroprotection

1999 • 170 citations

Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells

1995 • 169 citations

Activation of the metabotropic glutamate receptor attenuates N-methyl-D-aspartate neurotoxicity in cortical cultures.

1991 • 161 citations

Phospholipase C inhibitor, U73122, releases intracellular Ca2+, potentiates Ins(1,4,5)P3-mediated Ca2+ release and directly activates ion channels in mouse pancreatic acinar cells

1997 • 123 citations

Early postmitotic neurons transiently express TOAD‐64, a neural specific protein

1995 • 112 citations

Survival of dentate hilar mossy cells after pilocarpine-induced seizures and their synchronized burst discharges with area CA3 pyramidal cells

2001 • 111 citations

Group I mGluRs Increase Excitability of Hippocampal CA1 Pyramidal Neurons by a PLC-Independent Mechanism

2002 • 102 citations

Activation of metabotropic receptors has a neuroprotective effect in a rodent model of focal ischaemia

1992 • 90 citations

The distinct role of mGlu1 receptors in post-ischemic neuronal death

2003 • 89 citations

Activation of group I metabotropic glutamate receptors reduces neuronal apoptosis but increases necrotic cell death in vitro

2000 • 84 citations

Induction of LTD by activation of group I mGluR in the dentate gyrus in vitro

1999 • 83 citations

Group I and Group III metabotropic glutamate receptor subtypes provide enhanced neuroprotection

2000 • 76 citations

Altered expression of group I metabotropic glutamate receptors in the hippocampus of amygdala-kindled rats

1996 • 68 citations

Effect of chronic imipramine or electroconvulsive shock on the expression of mGluR1a and mGluR5a immunoreactivity in rat brain hippocampus

2002 • 58 citations

Neuroprotection against NMDA excitotoxicity by group I metabotropic glutamate receptors is associated with reduction of NMDA stimulated currents

2003 • 53 citations

Protective effect of group I metabotropic glutamate receptor activation against hypoxic/hypoglycemic injury in rat hippocampal slices: timing and involvement of protein kinase C

1999 • 48 citations

Suppression of Phospholipase C β, γ, and δ Families Alters Cell Growth and Phosphatidylinositol 4,5-Bisphosphate Levels

1997 • 37 citations

Activation of group I metabotropic glutamate receptors induces long-term depression at sensory synapses in superficial spinal dorsal horn

2000 • 34 citations

Glutamate-mediated neuroprotection against N-methyl-d-aspartate toxicity: a role for metabotropic glutamate receptors

2000 • 30 citations

Neuroprotective action of group I metabotropic glutamate receptor agonists against oxygen–glucose deprivation-induced neuronal death

2000 • 30 citations

Phosphoinositide hydrolysis in vivo with group I metabotropic glutamate receptor agonists

1999 • 23 citations

Changes in hippocampal gene expression after neuroprotective activation of group I metabotropic glutamate receptors

2003 • 22 citations

Two Compounds Commonly Used for Phospholipase C Inhibition Activate the Nuclear Estrogen Receptors

1999 • 19 citations

Inhibitors of phospholipase C prevent glutamate neurotoxicity in primary cultures of cerebellar neurons.

2000 • 19 citations

Antisense oligonucleotide against GTPase Rab5b inhibits metabotropic agonist DHPG-induced neuroprotection

2004 • 17 citations

Differential Expression of Rat Brain Phospholipase C Isozymes in Development and Aging

1998 • 14 citations