Lipid peroxidation, protein thiols and calcium homeostasis in bromobenzene-induced liver damage

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent

1968 • 7,671 citations

Bromobenzene-Induced Liver Necrosis. Protective Role of Glutathione and Evidence for 3,4-Bromobenzene Oxide as the Hepatotoxic Metabolite

1974 • 3,074 citations

Identification of 4-hydroxynonenal as a cytotoxic product originating from the peroxidation of liver microsomal lipids

1980 • 1,094 citations

Inhibition of the iron-catalysed formation of hydroxyl radicals from superoxide and of lipid peroxidation by desferrioxamine

1979 • 637 citations

Bleb Formation in Hepatocytes During Drug Metabolism Is Caused by Disturbances in Thiol and Calcium Ion Homeostasis

1982 • 553 citations

The toxicity of acetaminophen and N-acetyl-p-benzoquinone imine in isolated hepatocytes is associated with thiol depletion and increased cytosolic Ca2+.

1985 • 419 citations

Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes

1984 • 411 citations

Menadione-induced cytotoxicity is associated with protein thiol oxidation and alteration in intracellular Ca2+ homeostasis

1984 • 376 citations

Energy-dependent calcium sequestration activity in rat liver microsomes.

1975 • 342 citations

Acute paracetamol intoxication of starved mice leads to lipid peroxidation in vivo

1979 • 298 citations

Metabolic Activation of Drugs to Toxic Substances

1975 • 281 citations

Lipid peroxidation and cellular damage in extrahepatic tissues of bromobenzene-intoxicated mice.

1986 • 264 citations

Aldehydes in biological systems

1977 • 259 citations

Altered thiol and calcium homeostasis in oxidative hepatocellular injury

1985 • 249 citations

The role of glutathione in the retention of Ca2+ by liver mitochondria.

1984 • 223 citations

Drug-induced lipid peroxidation in mice—I Modulation by monooxegenase activity, glutathione and selenium status

1981 • 222 citations

Role of detoxifying enzymes in bromobenzene-induced liver necrosis.

1973 • 212 citations

Glutathione Depletion in Isolated Hepatocytes: Its Relation to Lipid Peroxidation and Cell Damage

1979 • 168 citations

Liver glutathione depletion induced by bromobenzene, iodobenzene, and diethylmaleate poisoning and its relation to lipid peroxidation and necrosis.

1985 • 159 citations

Bromobenzene Metabolism and Hepatic Necrosis

1971 • 141 citations

Mechanisms of cell injury in the killing of cultured hepatocytes by bromobenzene.

1982 • 135 citations

Role of redox cycling and lipid peroxidation in bipyridyl herbicide cytotoxicity

1986 • 133 citations

On the role of thiol groups in the inhibition of liver microsomal ca2+ sequestration by toxic agents

1985 • 93 citations

Paracetamol-stimulated lipid peroxidation in isolated rat and mouse hepatocytes

1983 • 91 citations

Stoichiometric Relationships in Mitochondrial Accumulation of Calcium and Phosphate Supported by Hydrolysis of Adenosine Triphosphate

1966 • 90 citations

Rat liver microsomal NADPH-dependent release of iron from ferritin and lipid peroxidation

1985 • 84 citations

Mechanisms of hepatocyte injury and death

1985 • 83 citations

Biochemical Mechanism of Hepatic Necrosis Induced by Aromatic Hydrocarbons

1973 • 78 citations

Detection of carbonyl functions in phospholipids of liver microsomes in CCl4- and BrCCl3-poisoned rats

1982 • 75 citations

The role of lipid peroxidation in the toxicity of foreign compounds to liver cells

1983 • 71 citations

The role of iron in the paracetamol- and CCl4-induced lipid peroxidation and hepatotoxicity

1985 • 65 citations

Detection of 4-hydroxynonenal and other lipid peroxidation products in the liver of bromobenzene-poisoned mice

1986 • 62 citations

Glutathione, lipid peroxidation and regulation of cytochrome P-450 activity

1982 • 47 citations

Glutathione Depletion, Lipid Peroxidation, and Liver Necrosis following Bromobenzene and lodobenzene Intoxication

1984 • 10 citations