Glutathione, lipid peroxidation and regulation of cytochrome P-450 activity

Tissue sulfhydryl groups

1959 • 25,130 citations

Glutathione S-Transferases

1974 • 17,321 citations

[30] Microsomal lipid peroxidation

1978 • 12,818 citations

The Role of Glutathione and Glutathione S-Transferases in the Metabolism of Chemical Carcinogens and Other Electrophilic Agents

1979 • 1,179 citations

The mechanism of NADPH-dependent lipid peroxidation. The propagation of lipid peroxidation.

1979 • 390 citations

Metal Ions in Biological Systems

1980 • 376 citations

Mechanistic aspects of enhanced lipid peroxidation following glutathione depletion in vivo

1981 • 276 citations

Lipid peroxide formation in microsomes. The role of non-haem iron

1969 • 276 citations

Lipid peroxidation and the degradation of cytochrome P-450 heme

1973 • 224 citations

Rat hepatic cytosolic glutathione-dependent enzyme protection against lipid peroxidation in the nadph-microsomal lipid peroxidation system

1980 • 175 citations

Glutathione Depletion in Isolated Hepatocytes: Its Relation to Lipid Peroxidation and Cell Damage

1979 • 168 citations

Microsomal lipid peroxidation. I. Characterization of the role of iron and NADPH.

1980 • 135 citations

Effects of lipid peroxidation on activities of drug-metabolizing enzymes in liver microsomes of rats

1973 • 105 citations

Regulation of Hepatic Glutathione Turnover in Rats In Vivo and Evidence for Kinetic Homogeneity of the Hepatic Glutathione Pool

1981 • 84 citations

Glutathione-dependent inhibition of lipid peroxidation by a soluble, heat-labile factor in animal tissues

1980 • 80 citations

Inhibition of hepatic microsomal lipid peroxidation by drug substrates without drug metabolism

1980 • 55 citations

Formation of N-(glutathion-S-methylene)-4-aminoazobenzene following metabolic oxidation of the N-methyl group of the carcinogen, N-methyl-4-aminoazobenzene

1982 • 33 citations

Metabolism of 4-Dimethylaminoazobenzene and Related Compounds. III. Metabolites of 4-Dimethylaminoazobenzene in Rat Bile and Influence of DAB Feeding on their Amounts

1963 • 24 citations

Biological reactive intermediates : formation, toxicity, and inactivation

1977 • 24 citations

Role of isozymes of cytochrome P-450 in the metabolism of N,N-dimethyl-4-aminoazobenzene in the rat.

1982 • 20 citations

Induction and inhibition of the metabolism and biliary excretion of the azo dye carcinogen, N,N-dimethyl-4-aminoazobenzene (DAB), in the rat.

1980 • 16 citations

A role for liver glutathione in the hepatobiliary fate of N,N-dimethyl-4-aminoazobenzene.

1979 • 13 citations

Biliary excretion of N,N-dimethyl-4-aminoazobenzene (DAB) in the rat. Effects of pretreatment with inducers and inhibitors of the mixed-function oxidase system and with agents that deplete liver glutathione.

1978 • 10 citations