Regulation of transendothelial permeability by Src Kinase

Regulated portals of entry into the cell

2003 • 3,642 citations

CELLULAR FUNCTIONS REGULATED BY SRC FAMILY KINASES

1997 • 2,470 citations

Signaling Mechanisms Regulating Endothelial Permeability

2005 • 1,632 citations

Loss of Caveolae, Vascular Dysfunction, and Pulmonary Defects in Caveolin-1 Gene-Disrupted Mice

2001 • 1,517 citations

Caveolin-1 Null Mice Are Viable but Show Evidence of Hyperproliferative and Vascular Abnormalities

2001 • 1,144 citations

Protein Tyrosine Kinase Structure and Function

2000 • 1,117 citations

Tubular membrane invaginations coated by dynamin rings are induced by GTP-γS in nerve terminals

1995 • 760 citations

Regulated internalization of caveolae.

1994 • 760 citations

Endocytosis Via Caveolae

2002 • 708 citations

PTRF-Cavin, a Conserved Cytoplasmic Protein Required for Caveola Formation and Function

2008 • 702 citations

Dynamin and Its Role in Membrane Fission

2000 • 689 citations

Structure and regulation of Src family kinases

2004 • 662 citations

Transcytosis: Crossing Cellular Barriers

2003 • 629 citations

The hunting of the Src

2001 • 584 citations

Regulation of vascular endothelial barrier function

1994 • 481 citations

Gp60 Activation Mediates Albumin Transcytosis in Endothelial Cells by Tyrosine Kinase-dependent Pathway

1997 • 371 citations

Impairment of dynamin's GAP domain stimulates receptor-mediated endocytosis

1999 • 364 citations

Tyrosine Phosphorylation of a 22-kDa Protein Is Correlated with Transformation by Rous Sarcoma Virus

1989 • 363 citations

Kinase-regulated quantal assemblies and kiss-and-run recycling of caveolae

2005 • 349 citations

Phosphorylation of Caveolin by Src Tyrosine Kinases

1996 • 347 citations

Caveolae-deficient Endothelial Cells Show Defects in the Uptake and Transport of Albumin in Vivo

2001 • 325 citations

Caveolin-2-Deficient Mice Show Evidence of Severe Pulmonary Dysfunction without Disruption of Caveolae

2002 • 318 citations

Albondin-mediated capillary permeability to albumin. Differential role of receptors in endothelial transcytosis and endocytosis of native and modified albumins.

1994 • 314 citations

New Roles for Src Kinases in Control of Cell Survival and Angiogenesis

2000 • 301 citations

Caveolin regulation of endothelial function

2003 • 297 citations

Endothelial Cell-Surface Gp60 Activates Vesicle Formation and Trafficking via Gi-Coupled Src Kinase Signaling Pathway

2000 • 289 citations

Regulation of Vascular Endothelial Growth Factor Receptor-2 Activity by Caveolin-1 and Plasma Membrane Cholesterol

2003 • 275 citations

Transcytosis of albumin in capillary endothelium.

1987 • 269 citations

A Critical Role of Cavin (Polymerase I and Transcript Release Factor) in Caveolae Formation and Organization

2007 • 261 citations

Domain structure and intramolecular regulation of dynamin GTPase

1997 • 239 citations

Protein kinase signaling in the modulation of microvascular permeability

2002 • 234 citations

Garrotes, Springs, Ratchets, and Whips: Putting Dynamin Models to the Test

2000 • 215 citations

Role of Src-induced Dynamin-2 Phosphorylation in Caveolae-mediated Endocytosis in Endothelial Cells

2004 • 211 citations

A Phosphotyrosine-dependent Protein Interaction Screen Reveals a Role for Phosphorylation of Caveolin-1 on Tyrosine 14

2002 • 203 citations

Vesicle formation and trafficking in endothelial cells and regulation of endothelial barrier function

2002 • 198 citations

Molecular determinants of endothelial transcytosis and their role in endothelial permeability

2007 • 177 citations

Dynamin GTPase Domain Mutants Block Endocytic Vesicle Formation at Morphologically Distinct Stages

2001 • 173 citations

Structure and function of endothelial caveolae

2002 • 167 citations

Src protein tyrosine kinase family and acute inflammatory responses

2006 • 165 citations

Transendothelial Transport: The Vesicle Controversy

2002 • 152 citations

Differential Caveolin-1 Polarization in Endothelial Cells during Migration in Two and Three Dimensions

2003 • 146 citations

The role(s) of Src kinase and Cbl proteins in the regulation of osteoclast differentiation and function

2005 • 146 citations

Src-dependent Tyrosine Phosphorylation Regulates Dynamin Self-assembly and Ligand-induced Endocytosis of the Epidermal Growth Factor Receptor

2002 • 143 citations

Endogenous Reactive Oxygen Intermediates Activate Tyrosine Kinases in Human Neutrophils

1996 • 142 citations

Plasmalemmal vesicles represent the large pore system of continuous microvascular endothelium

1993 • 137 citations

Intercellular Adhesion Molecule-1–Dependent Neutrophil Adhesion to Endothelial Cells Induces Caveolae-Mediated Pulmonary Vascular Hyperpermeability

2008 • 126 citations

Tyrosine-phosphorylated Caveolin-1: Immunolocalization and Molecular Characterization

1999 • 123 citations

VEGF-induced mobilization of caveolae and increase in permeability of endothelial cells

2002 • 122 citations

Epithelial Growth Factor-induced Phosphorylation of Caveolin 1 at Tyrosine 14 Stimulates Caveolae Formation in Epithelial Cells

2005 • 114 citations

Regulation of endothelial permeability by Src kinase signaling: Vascular leakage versus transcellular transport of drugs and macromolecules

2007 • 109 citations

Tyrosine phosphorylation‐dependence of caveolae‐mediated endocytosis

2007 • 107 citations

Crosstalk between the catalytic and regulatory domains allows bidirectional regulation of Src.

2000 • 104 citations

Transcytosis in the continuous endothelium of the myocardial microvasculature is inhibited by N-ethylmaleimide.

1994 • 102 citations

Dynamin Assembles into Spirals under Physiological Salt Conditions upon the Addition of GDP and γ-Phosphate Analogues

1997 • 100 citations

Gβγ Activation of Src Induces Caveolae-mediated Endocytosis in Endothelial Cells

2004 • 100 citations

Intersectin Regulates Fission and Internalization of Caveolae in Endothelial Cells

2003 • 98 citations

Functional and morphological studies of protein transcytosis in continuous endothelia

2004 • 96 citations

Caveolin Scaffolding Region and the Membrane Binding Region of Src Form Lateral Membrane Domains

2002 • 90 citations

The Src‐cortactin pathway is required for clustering of E‐selectin and ICAM‐1 in endothelial cells

2002 • 80 citations

Activation of SRC Tyrosine Kinases in Response to ICAM-1 Ligation in Pulmonary Microvascular Endothelial Cells

2003 • 79 citations

Src-dependent, neutrophil-mediated vascular hyperpermeability and β-catenin modification

2002 • 78 citations

Oxidative stress activates both Src-kinases and their negative regulator Csk and induces phosphorylation of two targeting proteins for Csk: caveolin-1 and paxillin

2003 • 76 citations

Transport of nitrated albumin across continuous vascular endothelium

2002 • 58 citations

Involvement of c-Src in diperoxovanadate-induced endothelial cell barrier dysfunction

2000 • 43 citations

Evidence of transcellular albumin transport after hemorrhagic shock.

2005 • 36 citations