Endocytosis Via Caveolae

Lipid rafts and signal transduction

2000 • 6,079 citations

FUNCTIONS OF LIPID RAFTS IN BIOLOGICAL MEMBRANES

1998 • 2,942 citations

Caveolin, a protein component of caveolae membrane coats

1992 • 2,230 citations

THE CAVEOLAE MEMBRANE SYSTEM

1998 • 1,947 citations

ENDOCYTOSIS AND MOLECULAR SORTING

1996 • 1,537 citations

Loss of Caveolae, Vascular Dysfunction, and Pulmonary Defects in Caveolin-1 Gene-Disrupted Mice

2001 • 1,517 citations

Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER

2001 • 1,236 citations

Caveolin-1 Null Mice Are Viable but Show Evidence of Hyperproliferative and Vascular Abnormalities

2001 • 1,144 citations

Caveolins, Liquid-Ordered Domains, and Signal Transduction

1999 • 1,016 citations

Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells

1993 • 961 citations

Filipin-sensitive caveolae-mediated transport in endothelium: reduced transcytosis, scavenger endocytosis, and capillary permeability of select macromolecules.

1994 • 894 citations

VIP21/caveolin is a cholesterol-binding protein.

1995 • 892 citations

THE FINE STRUCTURE OF THE GALL BLADDER EPITHELIUM OF THE MOUSE

1955 • 791 citations

Regulated internalization of caveolae.

1994 • 760 citations

Potocytosis: Sequestration and Transport of Small Molecules by Caveolae

1992 • 751 citations

Dynamin-mediated Internalization of Caveolae

1998 • 750 citations

Local Actin Polymerization and Dynamin Recruitment in SV40-Induced Internalization of Caveolae

2002 • 715 citations

Dynamin and Its Role in Membrane Fission

2000 • 689 citations

Dynamin at the Neck of Caveolae Mediates Their Budding to Form Transport Vesicles by GTP-driven Fission from the Plasma Membrane of Endothelium

1998 • 657 citations

Structure of simian virus 40 at 3.8-Å resolution

1991 • 643 citations

Caveolin-1 Regulates Transforming Growth Factor (TGF)-β/SMAD Signaling through an Interaction with the TGF-β Type I Receptor

2001 • 638 citations

Biological Basket Weaving: Formation and Function of Clathrin-Coated Vesicles

2001 • 626 citations

De novo formation of caveolae in lymphocytes by expression of VIP21-caveolin.

1995 • 597 citations

Membrane microdomains and caveolae

1999 • 580 citations

Caveolae and caveolins

1996 • 549 citations

VIP21, a 21-kD membrane protein is an integral component of trans-Golgi-network-derived transport vesicles.

1992 • 544 citations

Rapid Cycling of Lipid Raft Markers between the Cell Surface and Golgi Complex

2001 • 525 citations

Interleukin 2 Receptors and Detergent-Resistant Membrane Domains Define a Clathrin-Independent Endocytic Pathway

2001 • 513 citations

Sequestration of GPI-Anchored Proteins in Caveolae Triggered by Cross-Linking

1994 • 505 citations

VIP21-caveolin, a membrane protein constituent of the caveolar coat, oligomerizes in vivo and in vitro.

1995 • 465 citations

Caveolae and sorting in the trans-Golgi network of epithelial cells.

1993 • 461 citations

Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains

1999 • 456 citations

Caveolin-3 Null Mice Show a Loss of Caveolae, Changes in the Microdomain Distribution of the Dystrophin-Glycoprotein Complex, and T-tubule Abnormalities

2001 • 450 citations

The glycophospholipid-linked folate receptor internalizes folate without entering the clathrin-coated pit endocytic pathway.

1990 • 444 citations

Caveolae Are Highly Immobile Plasma Membrane Microdomains, Which Are not Involved in Constitutive Endocytic Trafficking

2002 • 431 citations

Non-coated membrane invaginations are involved in binding and internalization of cholera and tetanus toxins

1982 • 428 citations

Caveolin moves from caveolae to the Golgi apparatus in response to cholesterol oxidation.

1994 • 425 citations

Endocytosis without clathrin coats

2001 • 418 citations

Penetration of semliki forest virus from acidic prelysosomal vacuoles

1983 • 411 citations

Actin Assembly Plays a Variable, but not Obligatory Role in Receptor‐Mediated Endocytosis

2000 • 385 citations

Bound simian virus 40 translocates to caveolin-enriched membrane domains, and its entry is inhibited by drugs that selectively disrupt caveolae.

1996 • 384 citations

Internalization of cholera toxin by different endocytic mechanisms

2001 • 383 citations

PI(4,5)P2 regulation of surface membrane traffic

2001 • 377 citations

Endothelial Caveolae Have the Molecular Transport Machinery for Vesicle Budding, Docking, and Fusion Including VAMP, NSF, SNAP, Annexins, and GTPases

1995 • 370 citations

Tyrosine Phosphorylation of a 22-kDa Protein Is Correlated with Transformation by Rous Sarcoma Virus

1989 • 363 citations

Caveolin Is Palmitoylated on Multiple Cysteine Residues

1995 • 356 citations

Caveolin-3 Associates with Developing T-tubules during Muscle Differentiation

1997 • 345 citations

Clathrin-dependent and -independent internalization of plasma membrane sphingolipids initiates two Golgi targeting pathways

2001 • 319 citations

Involvement of Cellular Caveolae in Bacterial Entry into Mast Cells

2000 • 317 citations

Clusters of glycolipid and glycosylphosphatidylinositol-anchored proteins in lymphoid cells : accumulation of actin regulated by local tyrosine phosphorylation

1999 • 316 citations

A Caveolin Dominant Negative Mutant Associates with Lipid Bodies and Induces Intracellular Cholesterol Imbalance

2001 • 313 citations

Identification of Filamin as a Novel Ligand for Caveolin-1: Evidence for the Organization of Caveolin-1–associated Membrane Domains by the Actin Cytoskeleton

2000 • 303 citations

The structure of simian virus 40 refined at 3.1 å resolution

1996 • 297 citations

Structure of murine polyomavirus complexed with an oligosaccharide receptor fragment

1994 • 295 citations

Intracellular cholesterol transport

1997 • 295 citations

NEW EMBO MEMBERS' REVIEW: Actin cytoskeleton regulation through modulation of PI(4,5)P2 rafts

2001 • 289 citations

Endothelial Cell-Surface Gp60 Activates Vesicle Formation and Trafficking via Gi-Coupled Src Kinase Signaling Pathway

2000 • 289 citations

Modulation of phagosome biogenesis by Legionella pneumophila creates an organelle permissive for intracellular growth

1999 • 281 citations

Lipid rafts and HIV-1: from viral entry to assembly of progeny virions

2001 • 273 citations

Penetration of protein toxins into cells

2000 • 264 citations

Endocytosis of simian virus 40 into the endoplasmic reticulum.

1989 • 257 citations

Accumulation of Caveolin in the Endoplasmic Reticulum Redirects the Protein to Lipid Storage Droplets

2001 • 242 citations

Major histocompatibility complex class I molecules mediate association of SV40 with caveolae.

1997 • 242 citations

Caveolin-2 Is Targeted to Lipid Droplets, a New “Membrane Domain” in the Cell

2001 • 238 citations

Caveolin-1 Is a Negative Regulator of Caveolae-mediated Endocytosis to the Endoplasmic Reticulum

2002 • 235 citations

Internalization of Echovirus 1 in Caveolae

2002 • 220 citations

Garrotes, Springs, Ratchets, and Whips: Putting Dynamin Models to the Test

2000 • 215 citations

Caveolin forms a hetero-oligomeric protein complex that interacts with an apical GPI-linked protein: implications for the biogenesis of caveolae.

1993 • 197 citations

Tyrosine Phosphorylation of Caveolin-1 in the Endothelium

1999 • 197 citations

Immunoisolation and partial characterization of endothelial plasmalemmal vesicles (caveolae).

1997 • 195 citations

Involvement of caveolae in the uptake of respiratory syncytial virus antigen by dendritic cells

1999 • 193 citations

Endocytosis of GPI-linked membrane folate receptor-alpha.

1996 • 188 citations

Analysis of retrograde transport in motor neurons reveals common endocytic carriers for tetanus toxin and neurotrophin receptor p75NTR

2002 • 173 citations

Lipid Rafts Act as Specialized Domains for Tetanus Toxin Binding and Internalization into Neurons

2001 • 168 citations

The function of dynamin in endocytosis

1995 • 159 citations

Cholera Toxin Is Found in Detergent-insoluble Rafts/Domains at the Cell Surface of Hippocampal Neurons but Is Internalized via a Raft-independent Mechanism

2001 • 153 citations

High affinity binding, endocytosis, and degradation of conformationally modified albumins. Potential role of gp30 and gp18 as novel scavenger receptors.

1993 • 148 citations

Caveolae Are Involved in the Trafficking of Mouse Polyomavirus Virions and Artificial VP1 Pseudocapsids toward Cell Nuclei

2001 • 147 citations

Caveolins and Cellular Cholesterol Balance

2000 • 145 citations

Endothelial plasmalemmal vesicles have a characteristic striped bipolar surface structure.

1985 • 140 citations

HOW DO ANIMAL DNA VIRUSES GET TO THE NUCLEUS?

1998 • 131 citations

Early events in polyoma virus infection: attachment, penetration, and nuclear entry

1976 • 129 citations

Localization of Autocrine Motility Factor Receptor to Caveolae and Clathrin-independent Internalization of Its Ligand to Smooth Endoplasmic Reticulum

1998 • 119 citations

THE PHYSIOLOGICAL RELATION OF PLANT CAROTINOIDS TO THE CAROTINOIDS OF THE COW, HORSE, SHEEP, GOAT, PIG, AND HEN

1916 • 119 citations

Isolation, Cloning, and Localization of Rat PV-1, a Novel Endothelial Caveolar Protein

1999 • 116 citations

Induction of Caveolae in the Apical Plasma Membrane of Madin-Darby Canine Kidney Cells

1999 • 113 citations

Class I major histocompatibility proteins are an essential component of the simian virus 40 receptor

1992 • 111 citations

Morphological Aspects of the Uptake of Simian Virus 40 by Permissive Cells

1970 • 110 citations

Class I major histocompatibility proteins as cell surface receptors for simian virus 40

1989 • 105 citations

Extracellular Simian Virus 40 Transmits a Signal That Promotes Virus Enclosure within Caveolae

1999 • 100 citations

Dynamin mediates caveolar sequestration of muscarinic cholinergic receptors and alteration in NO signaling

2000 • 100 citations

Role of Cholesterol in Developing T‐Tubules: Analogous Mechanisms for T‐Tubule and Caveolae Biogenesis

2000 • 95 citations

Import of simian virus 40 virions through nuclear pore complexes.

1991 • 86 citations

Early Steps of Polyomavirus Entry into Cells

2000 • 75 citations

Role of nuclear pore complex in simian virus 40 nuclear targeting

1993 • 74 citations

Extracellular Simian Virus 40 Induces an ERK/MAP Kinase-independent Signalling Pathway that Activates Primary Response Genes and Promotes Virus Entry

1996 • 74 citations

MHC class I molecules are enriched in caveolae but do not enter with simian virus 40.

1998 • 74 citations

Membrane fusion as a mechanism of simian virus 40 entry into different cellular compartments

1978 • 72 citations

Exploitation of major histocompatibility complex class I molecules and caveolae by simian virus 40

1999 • 64 citations

High Sensitivity of Mouse Neuronal Cells to Tetanus Toxin Requires a GPI-Anchored Protein

2001 • 59 citations

Withdrawal of ?Caveolae and Their Coat Proteins, the Caveolins: From Electron Microscopic Novelty to Biological Launching Pad? [Journal of Cellular Physiology 186(3) 329-337 (2001)]

2001 • 57 citations

Caveolin Internalization by Heat Shock or Hyperosmotic Shock

2000 • 47 citations

Effects of inhibitors of the cytoplasmic structures and functions on the early phase of infection of cultured cells with simian virus 40

1987 • 40 citations

Clathrin-mediated endocytosis and recycling of autocrine motility factor receptor to fibronectin fibrils is a limiting factor for NIH-3T3 cell motility

2000 • 31 citations

Simian Virus 40 Infection Is Not Mediated by Lysosomal Activation

1987 • 15 citations

Role of cholesterol in organisation of developing T-tubules; analogous mechanisms for T-tubule and caveolae biogenesis

2000 • 12 citations