Regulation of Short‐Term Changes in Hepatic β‐Hydroxy‐β‐methylglutaryl‐CoA Reductase Activity

Biosynthesis of isoprenoid compounds

1982 • 561 citations

Modulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity with cAMP and with protein fractions of rat liver cytosol

1973 • 309 citations

Active and inactive forms of 3-hydroxy-3-methylglutaryl coenzyme A reductase in the liver of the rat. Comparison with the rate of cholesterol synthesis in different physiological states.

1979 • 309 citations

Purification and properties of rabbit liver phosphorylase phosphatase.

1975 • 274 citations

[91] Immunoaffinity chromatography of proteins

1974 • 255 citations

Interconversion of active and inactive forms of rat liver hydroxymethylglutaryl-CoA reductase.

1977 • 231 citations

3-Hydroxy-3-methylglutaryl coenzyme A reductase: regulation of enzymatic activity by phosphorylation and dephosphorylation.

1978 • 143 citations

Modulation of hydroxymethylglutaryl-CoA reductase activity, reductase kinase activity, and cholesterol synthesis in rat hepatocytes in response to insulin and glucagon.

1979 • 143 citations

Reversible modulation of the activities of both liver microsomal hydroxymethylglutaryl coenzyme a reductase and its inactivating enzyme. Evidence for regulation by phosphorylation-dephosphorylation

1978 • 142 citations

The mechanism of the diurnal variation of hepatic HMG-CoA reductase activity in the rat

1971 • 119 citations

Properties of purified rat hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase and regulation of enzyme activity.

1980 • 118 citations

Factors affecting the diurnal variation in the level of β-hydroxy-β-methylglutaryl coenzyme A reductase and cholesterol-synthesizing activity in rat liver

1972 • 111 citations

In vitro and in vivo phosphorylation of rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase and its modulation by glucagon.

1980 • 96 citations

Purification and Subunit Structure of a High-Molecular-Weight Phosphoprotein Phosphatase (Phosphatase 11) from Rat Liver

1980 • 87 citations

Dissociation and exchange of the beta 2-microglobulin subunit of HLA-A and HLA-B antigens.

1979 • 81 citations

Rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase: A comparison and immunological study of purified solubilized preparations, and alteration of enzyme levels by cholestyramine feeding

1974 • 62 citations

In vivo and in vitro mechanisms regulating rat liver beta-hydroxy-beta-methylglutaryl coenzyme A reductase activity.

1980 • 52 citations

In vivo regulation of rat liver 3-hydroxy-3-methylglutaryl-coenzyme A reductase: enzyme phosphorylation as an early regulatory response after intragastric administration of mevalonolactone.

1980 • 43 citations

In vivo effect of cholesterol feeding on the short term regulation of hepatic hydroxymethylglutaryl coenzyme A reductase during the diurnal cycle.

1981 • 42 citations

Reversible modulation of rat liver 3-hydroxy 3-methyl glutaryl coenzyme a reductase Evidence for an enzyme-catalyzed phosphorylation-dephosphorylation system

1978 • 40 citations

[55] 3-Hydroxy-3-methylglutaryl-CoA reductase from rat liver

1981 • 33 citations

Immunotitration of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in various physiological states.

1979 • 29 citations

3-Hydroxy-3-methylglutaryl-coenzyme A reductase. A comparison of the modulation in vitro by phosphorylation and dephosphorylation to modulation of enzyme activity by feeding cholesterol- or cholestyramine-supplemented diets

1980 • 19 citations

Characteristics of magnesium-adenosine triphosphate-dependent inactivators of 3-hydroxy-3-methylglutaryl coenzyme A reductase.

1980 • 18 citations