Interconversion of active and inactive forms of rat liver hydroxymethylglutaryl-CoA reductase.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Determination of molecular weights and frictional ratios of proteins in impure systems by use of gel filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases

1966 • 2,239 citations

Regulation of HMG-CoA Reductase

1976 • 743 citations

The use of Coomassie Brilliant Blue G250 perchloric acid solution for staining in electrophoresis and isoelectric focusing on polyacrylamide gels

1975 • 622 citations

Suppression of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Activity and Inhibition of Growth of Human Fibroblasts by 7-Ketocholesterol

1974 • 502 citations

Micro assay for 3-hdyroxy-3-methylglutaryl-CoA reductase in rat liver and in L-cell fibroblasts

1974 • 408 citations

Inhibition of Sterol Synthesis in Cultured Mouse Cells by Cholesterol Derivatives Oxygenated in the Side Chain

1974 • 330 citations

Inhibition of Sterol Synthesis in Cultured Mouse Cells by 7α-Hydroxycholesterol, 7β-Hydroxycholesterol, and 7-Ketocholesterol

1973 • 320 citations

Modulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity with cAMP and with protein fractions of rat liver cytosol

1973 • 309 citations

Regulation of Hepatic 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase and Cholesterol Synthesis

1971 • 252 citations

3-Hydroxy-3-methylglutaryl Coenzyme A Reductase

1973 • 240 citations

Improved assay of 3-hydroxy-3-methylglutaryl coenzyme A reductase

1971 • 177 citations

Regulation of Hepatic 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase

1972 • 154 citations

Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in hepatoma tissue culture cells by pure cholesterol and several cholesterol derivatives. Evidence supporting two distinct mechanisms.20l.

1976 • 149 citations

The mechanism of the diurnal variation of hepatic HMG-CoA reductase activity in the rat

1971 • 119 citations

Control of 3-hydroxy-3-methylglutaryl coenzyme A reductase by endogenously synthesized sterols in vitro and in vivo.

1977 • 110 citations

Inactivation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in vitro. An adenine nucleotide-dependent reaction catalyzed by a factor in human fibroblasts.

1975 • 98 citations

Regulation of Rat Liver β-Hydroxy-β-Methylglutaryl-CoA Reductase Activity by Cholesterol

1973 • 97 citations

Investigation of regulation of microsomal hydroxymethylglutaryl coenzyme A reductase and methyl sterol oxidase of cholesterol biosynthesis.

1977 • 73 citations

Regulation of 3-hydroxy-3-methylglutaryl coenzyme a reductase in minimal deviation hepatoma 7288C. Immunological measurements in hepatoma tissue culture cells.

1977 • 46 citations

Regulation of hydroxymethylglutaryl-CoA reductase in rat leukocytes

1977 • 42 citations

Determination of the michaelis-menten constant for beta-hydroxy-beta-methylglutaryl coenzyme A reductase. Demonstration of a substrate affinity 10-fold greater than previously reported.

1976 • 37 citations

Characterization of sand as a support for immobilized enzymes

1976 • 37 citations

Specific Activation of in Vitro Cholesterol Biosynthesis by Preincubation of Rat Liver Homogenates

1973 • 35 citations

Activation of 3-Hydroxy-3-methylglutaryl-Coenzyme A Reductase in vitro

1976 • 33 citations

Properties of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Solubilized from Rat Liver and Hepatoma

1974 • 30 citations

The inhibitory effect of ATP on HMGCoA reductase

1975 • 25 citations