Disease-associated Autoimmunity and Prevention of Insulin-dependent Diabetes Mellitus

TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties

1989 • 7,558 citations

A genome-wide search for human type 1 diabetes susceptibility genes

1994 • 1,294 citations

Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases

1995 • 1,120 citations

Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes

1993 • 1,087 citations

Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice

1993 • 962 citations

Prediction of Type I Diabetes in First-Degree Relatives Using a Combination of Insulin, GAD, and ICA512bdc/IA-2 Autoantibodies

1996 • 788 citations

Purified protein derivative of Mycobacterium tuberculosis and excretory-secretory antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production.

1991 • 705 citations

Cow's Milk Exposure and Type I Diabetes Mellitus: A critical overview of the clinical literature

1994 • 439 citations

A Prospective Study of the Role of Coxsackie B and Other Enterovirus Infections in the Pathogenesis of IDDM

1995 • 423 citations

Genetic mapping of a susceptibility locus for insulin-dependent diabetes mellitus on chromosome llq

1994 • 397 citations

Immunoregulatory and Cytokine Imbalances in the Pathogenesis of IDDM: Therapeutic Intervention by Immunostimulation?

1994 • 363 citations

Combined Analysis of Autoantibodies Improves Prediction of IDDM in Islet Cell Antibody-Positive Relatives

1994 • 360 citations

Prediction of insulin-dependent diabetes mellitus in siblings of children with diabetes. A population-based study. The Childhood Diabetes in Finland Study Group.

1998 • 283 citations

Response of peripheral-blood mononuclear cells to glutamate decarboxylase in insulin-dependent diabetes

1992 • 275 citations

Induction of Autoimmune Diabetes by Oral Administration of Autoantigen

1996 • 261 citations

Inverse relation between humoral and cellular immunity to glutamic acid decarboxylase in subjects at risk of insulin-dependent diabetes

1993 • 247 citations

Maternal Enteroviral Infection During Pregnancy as a Risk Factor for ChildHood IDDM: A Population-Based Case-Control Study

1995 • 213 citations

Antiislet autoantibodies usually develop sequentially rather than simultaneously.

1996 • 201 citations

Cellular Immune Response to Diverse Islet Cell Antigens in IDDM

1996 • 123 citations

Interactions of Age, Islet Cell Antibodies, Insulin Autoantibodies, and First-Phase Insulin Response in Predicting Risk of Progression to IDDM in ICA+ Relatives: The ICARUS Data Set

1996 • 122 citations

Population based study of prevalence of islet cell autoantibodies in monozygotic and dizygotic Danish twin pairs with insulin dependent diabetes mellitus

1997 • 42 citations

An Overview on Possible Mechanisms of Destruction of the Insulin-Producing Beta Cell

1990 • 42 citations

Disease-Associated Antibodies in Offspring of Mothers with IDDM

1996 • 35 citations

Interaction of genetic and environmental factors in the pathogenesis of insulin-dependent diabetes mellitus

1997 • 30 citations

Islet cell autoantigens in type 1 diabetes

1996 • 22 citations

HLA-DQB1 genotypes associated with IDDM risk in healthy school children positive for GAD65 and islet cell antibodies

1996 • 6 citations

American Diabetes Association Scientific Sessions, 1995: IDDM: Treatment and Prevention

1996 • 4 citations

Cow's milk consumption associated with disease specific autoantibodies in siblings of children with IDDM

1997 • 1 citations