Function and assembly of the Leishmania surface coat

The structure, biosynthesis and function of glycosylated phosphatidylinositols in the parasitic protozoa and higher eukaryotes

1993 • 896 citations

The dolichol pathway of N-linked glycosylation

1999 • 634 citations

The structure, biosynthesis and functions of glycosylphosphatidylinositol anchors, and the contributions of trypanosome research

1999 • 622 citations

The Interaction of Leishmania Species with Macrophages

1992 • 323 citations

Lipophosphoglycan is a virulence factor distinct from related glycoconjugates in the protozoan parasiteLeishmania major

2000 • 298 citations

Developmental modification of lipophosphoglycan during the differentiation of Leishmania major promastigotes to an infectious stage.

1992 • 263 citations

Use of the green fluorescent protein as a marker in transfected Leishmania

1996 • 255 citations

Developmental changes in the glycosylated phosphatidylinositols of Leishmania donovani. Characterization of the promastigote and amastigote glycolipids

1991 • 235 citations

Structures of the glycoinositolphospholipids from Leishmania major. A family of novel galactofuranose-containing glycolipids.

1990 • 229 citations

Glycoconjugates in Leishmania infectivity

1999 • 218 citations

Metacyclogenesis in Leishmania promastigotes

1989 • 215 citations

The role of phosphoglycans inLeishmania–sand fly interactions

2000 • 198 citations

Surface acid proteinase (gp63) of Leishmania mexicana

1989 • 196 citations

Biosynthesis of glycosyl-phosphatidylinositol lipids in Trypanosoma brucei: involvement of mannosyl-phosphoryldolichol as the mannose donor.

1990 • 187 citations

Identification and purification of membrane and soluble forms of the major surface protein of Leishmania promastigotes.

1985 • 180 citations

Stage-specific binding of Leishmania donovani to the sand fly vector midgut is regulated by conformational changes in the abundant surface lipophosphoglycan.

1995 • 179 citations

Lipophosphoglycan (LPG) and the identification of virulence genes in the protozoan parasite Leishmania

1998 • 165 citations

Serum resistance of metacyclic stage Leishmania major promastigotes is due to release of C5b-9.

1990 • 164 citations

A Specialized Pathway Affecting Virulence Glycoconjugates of Leishmania

1995 • 156 citations

Golgi GDP-mannose Uptake Requires Leishmania LPG2

1997 • 149 citations

Endocytosis and secretion in trypanosomatid parasites — Tumultuous traffic in a pocket

1997 • 145 citations

Early lipid intermediates in glycosyl-phosphatidylinositol anchor assembly are synthesized in the ER and located in the cytoplasmic leaflet of the ER membrane bilayer.

1993 • 143 citations

N-Glycosylation in trypanosomatid protozoa

1993 • 143 citations

Recent developments in the cell biology and biochemistry of glycosylphosphatidylinositol lipids (Review)

2000 • 135 citations

Lipophosphoglycan is not required for infection of macrophages or mice by Leishmania mexicana

2000 • 134 citations

Structure of Leishmania lipophosphoglycan: inter- and intra-specific polymorphism in Old World species

1995 • 128 citations

Passive transfer of Leishmania lipopolysaccharide confers parasite survival in macrophages.

1986 • 127 citations

The comparative fine structure and surface glycoconjugate expression of three life stages of Leishmania major

1991 • 127 citations

Isolation of virulence genes directing surface glycosyl-phosphatidylinositol synthesis by functional complementation of Leishmania.

1993 • 125 citations

Transport and sorting of membrane lipids

1993 • 123 citations

Expression of lipophosphoglycan, high-molecular weight phosphoglycan and glycoprotein 63 in promastigotes and amastigotes of Leishmania mexicana

1993 • 121 citations

The glycoinositol phospholipids of Leishmania mexicana promastigotes. Evidence for the presence of three distinct pathways of glycolipid biosynthesis

1993 • 120 citations

Targeted gene deletion of Leishmania major genes encoding developmental stage‐specific leishmanolysin (GP63)

1998 • 118 citations

The major surface antigens of Entamoeba histolytica trophozoites are GPI-anchored proteophosphoglycans

2000 • 109 citations

Delineation of Three Pathways of Glycosylphosphatidylinositol Biosynthesis in Leishmania mexicana

1998 • 108 citations

Episomal Expression of Specific Sense and Antisense mRNAs inLeishmania amazonensis: Modulation of gp63 Level in Promastigotes and Their Infection of Macrophages In Vitro

2000 • 95 citations

Distribution of GPI-anchored proteins in the protozoan parasite Leishmania, based on an improved ultrastructural description using high-pressure frozen cells

2000 • 94 citations

Golgi-mediated post-translational processing of secretory acid phosphatase by Leishmania donovani promastigotes

1990 • 91 citations

Expression of the major surface glycoprotein of Leishmania donovani chagasi in virulent and attenuated promastigotes.

1989 • 91 citations

Glycosylphosphatidylinositol biosynthetic enzymes are localized to a stable tubular subcompartment of the endoplasmic reticulum in Leishmania mexicana

1999 • 87 citations

Evidence that free GPI glycolipids are essential for growth of Leishmania mexicana

1999 • 87 citations

Deficiency in β1,3-Galactosyltransferase of a Leishmania major Lipophosphoglycan Mutant Adversely Influences the Leishmania-Sand Fly Interaction

1996 • 85 citations

Surface antigens of Leishmania mexicana amastigotes: characterization of glycoinositol phospholipids and a macrophage-derived glycosphingolipid

1994 • 84 citations

Leishmania mexicanaMutants Lacking Glycosylphosphatidylinositol (GPI):Protein Transamidase Provide Insights into the Biosynthesis and Functions of GPI-anchored Proteins

2000 • 80 citations

Selective inhibitors of the glycosylphosphatidylinositol biosynthetic pathway of Trypanosoma brucei

1999 • 80 citations

The structure of Leishmania major amastigote lipophosphoglycan.

1993 • 77 citations

O- and N-glycosylation of the Leishmania mexicana-secreted acid phosphatase. Characterization of a new class of phosphoserine-linked glycans.

1994 • 77 citations

The role of the lipophosphoglycan ofLeishmaniain vector competence

1994 • 70 citations

Comparison of Extracellular Acid Phosphatases from Various Isolates of Leishmania

1986 • 69 citations

The glycoinositolphospholipid profiles of two Leishmania major strains that differ in lipophosphoglycan expression

1990 • 67 citations

Molecular Cloning and Characterization of a Novel Repeat-containing Leishmania major Gene,ppg1, That Encodes a Membrane-associated Form of Proteophosphoglycan with a Putative Glycosylphosphatidylinositol Anchor

1999 • 65 citations

Characterization of polymer release from the flagellar pocket of Leishmania mexicana promastigotes.

1994 • 61 citations

Genetic rescue of surface metalloproteinase (gp63)-deficiency in Leishmania amazonensis variants increases their infection of macrophages at the early phase

1994 • 53 citations

Proteophosphoglycans from Leishmania promastigotes and amastigotes

1999 • 52 citations

Purification, partial characterization and immunolocalization of a proteophosphoglycan secreted by Leishmania mexicana amastigotes.

1995 • 52 citations

Cell surface nanoanatomy of Leishmania major as revealed by fracture-flip. A surface meshwork of 44 nm fusiform filaments identifies infective developmental stage promastigotes.

1989 • 42 citations

Early steps in glycosylphosphatidylinositol biosynthesis in Leishmania major

1997 • 42 citations

Biosynthesis of the glycolipid anchor of lipophosphoglycan and the structurally related glycoinositolphospholipids from Leishmania major

1995 • 42 citations

Identification of the defect in lipophosphoglycan biosynthesis in a non-pathogenic strain of Leishmania major.

1992 • 41 citations

N-Glycosylation as a biochemical basis for virulence in Leishmania mexicana amazonensis

1988 • 35 citations

Compositional analysis of Glucosaminyl(acyl)phosphatidylinositol Accumulated in HeLa S3 Cells

1995 • 23 citations