A Specialized Pathway Affecting Virulence Glycoconjugates of Leishmania

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Basic local alignment search tool

1990 • 87,358 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

The structure, biosynthesis and function of glycosylated phosphatidylinositols in the parasitic protozoa and higher eukaryotes

1993 • 896 citations

THE LIPOPHOSPHOGLYCAN OF LEISHMANIA PARASITES

1992 • 473 citations

Bacterial cell wall

1996 • 450 citations

Production of homozygous mutant ES cells with a single targeting construct.

1992 • 418 citations

Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection.

1994 • 365 citations

Double targeted gene replacement for creating null mutants.

1991 • 323 citations

Biosynthesis and Expression of Cell-Surface Polysaccharides in Gram-Negative Bacteria

1993 • 251 citations

Heavy metal resistance: a new role for P-glycoproteins in Leishmania.

1991 • 231 citations

PTR1: a reductase mediating salvage of oxidized pteridines and methotrexate resistance in the protozoan parasite Leishmania major.

1994 • 187 citations

Requirement of lipophosphoglycan for intracellular survival of Leishmania donovani within human monocytes.

1990 • 144 citations

Passive transfer of Leishmania lipopolysaccharide confers parasite survival in macrophages.

1986 • 127 citations

Isolation of virulence genes directing surface glycosyl-phosphatidylinositol synthesis by functional complementation of Leishmania.

1993 • 125 citations

The immunochemical structure and surface arrangement of Leishmania donovani lipophosphoglycan determined using monoclonal antibodies

1989 • 116 citations

Expression of an unusual acidic glycoconjugate in Leishmania donovani.

1984 • 107 citations

The Leishmania donovani lipophosphoglycan T lymphocyte-reactive component is a tightly associated protein complex.

1991 • 92 citations

Golgi-mediated post-translational processing of secretory acid phosphatase by Leishmania donovani promastigotes

1990 • 91 citations

A ricin agglutinin-resistant clone of Leishmania donovani deficient in lipophosphoglycan

1988 • 86 citations

Isolation and structural characterization of the Leishmania donovani kinetoplastid membrane protein-11, a major immunoreactive membrane glycoprotein

1995 • 85 citations

Characterization of phosphoglycan-containing secretory products ofLeishmania

1994 • 74 citations

Expression of a hydrophilic surface protein in infective stages of Leishmania major

1994 • 71 citations

The role of the lipophosphoglycan ofLeishmaniain vector competence

1994 • 70 citations

Sodium orthovanadate-resistant mutants of Saccharomyces cerevisiae show defects in Golgi-mediated protein glycosylation, sporulation and detergent resistance.

1995 • 67 citations

Characterization of two proteins from Leishmania donovani and their use for vaccination against visceral leishmaniasis.

1990 • 64 citations

Monoclonal antibodies directed against Leishmania secreted acid phosphatase and lipophosphoglycan

1993 • 63 citations

Lipophosphoglycan expression and virulence in Ricin-resistant variants of Leishmania major

1990 • 59 citations

Defective galactofuranose addition in lipophosphoglycan biosynthesis in a mutant of Leishmania donovani.

1993 • 57 citations

Acid phosphatase activity of virulent and avirulent clones of Leishmania donovani promastigotes

1988 • 57 citations

A New Role

1970 • 55 citations

Leishmania donovani: Immunochemical localization and secretory mechanism of soluble acid phosphatase

1989 • 54 citations

Cell-free biosynthesis of lipophosphoglycan from Leishmania donovani. Characterization of microsomal galactosyltransferase and mannosyltransferase activities

1991 • 53 citations

Characterization of Leishmania donovani variant clones using anti-lipophosphoglycan monoclonal antibodies

1990 • 38 citations

Monoclonal antibodies to Leishmania mexicana promastigote antigens I. Secreted acid phosphatase and other proteins share epitopes with lipophosphoglycan

1991 • 38 citations

Biosynthesis of lipophosphoglycan from Leishmania donovani: Characterization of mannosylphosphate transfer in vitro

1992 • 37 citations

Ricin-resistant mutants ofLeishmania majorwhich express modified lipophosphoglycan remain infective for mice

1994 • 20 citations

Biosynthesis of lipophosphoglycan from Leishmania major: characterization of (β1-3)-galactosyltransferase(s)

1994 • 19 citations

Effect of tunicamycin on the extracellular acid phosphatase of Leishmania donovani promastigotes

1987 • 19 citations

Cell surface components of Leishmania: identification of a novel parasite lectin?

1995 • 15 citations

Deleted Work

1955 • 0 citations