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Integrin, A Transmembrane Glycoprotein Complex Mediating Cell-Substratum Adhesion

Data up to Jan 2025

Published1987
Citations176
References53

Total Citations Per Year

Abstract

References (53)

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Arg-Gly-Asp: A versatile cell recognition signal

1986 • 1,413 citations

Interaction of plasma membrane fibronectin receptor with talin—a transmembrane linkage

1986 • 1,206 citations

Identification and isolation of a 140 kd cell surface glycoprotein with properties expected of a fibronectin receptor

1985 • 1,119 citations

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1983 • 888 citations

Structure of integrin, a glycoprotein involved in the transmembrane linkage between fibronectin and actin

1986 • 854 citations

Cell Surface Receptors for Extracellular Matrix Molecules

1987 • 793 citations

Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3.

1982 • 740 citations

The effect of Arg-Gly-Asp-containing peptides on fibrinogen and von Willebrand factor binding to platelets.

1985 • 594 citations

Cloning of the $beta; subunit of the leukocyte adhesion proteins: Homology to an extracellular matrix receptor defines a novel supergene family

1987 • 520 citations

A 125/115-kDa cell surface receptor specific for vitronectin interacts with the arginine-glycine-aspartic acid adhesion sequence derived from fibronectin.

1985 • 517 citations

The VLA protein family. Characterization of five distinct cell surface heterodimers each with a common 130,000 molecular weight beta subunit.

1987 • 512 citations

The cell substrate attachment (CSAT) antigen has properties of a receptor for laminin and fibronectin.

1985 • 503 citations

Biologically active synthetic peptides as probes of embryonic development: a competitive peptide inhibitor of fibronectin function inhibits gastrulation in amphibian embryos and neural crest cell migration in avian embryos.

1984 • 429 citations

Phosphorylation of the fibronectin receptor complex in cells transformed by oncogenes that encode tyrosine kinases.

1986 • 355 citations

Alterations in neural crest migration by a monoclonal antibody that affects cell adhesion.

1985 • 322 citations

Development of cell surface linkage complexes in cultured fibroblasts.

1985 • 320 citations

Cell surface proteoglycan associates with the cytoskeleton at the basolateral cell surface of mouse mammary epithelial cells.

1986 • 314 citations

A monoclonal antibody detaches embryonic skeletal muscle from extracellular matrices.

1982 • 310 citations

Cell adhesion and migration in the early vertebrate embryo: location and possible role of the putative fibronectin receptor complex

1986 • 309 citations

Distribution of the cell substratum attachment (CSAT) antigen on myogenic and fibroblastic cells in culture.

1985 • 293 citations

cDNA and amino acid sequences of the cell adhesion protein receptor recognizing vitronectin reveal a transmembrane domain and homologies with other adhesion protein receptors.

1986 • 231 citations

Fibronectin receptor structures in the VLA family of heterodimers

1987 • 230 citations

Rous sarcoma virus-transformed fibroblasts and cells of monocytic origin display a peculiar dot-like organization of cytoskeletal proteins involved in microfilament-membrane interactions*1

1987 • 216 citations

Monoclonal Antibodies Which Alter the Morphology of Cultured Chick Myogenic Cells

1982 • 212 citations

Characterization of a novel differentiation antigen complex recognize by a monoclonal antibody (A-1A5): unique activation-specific molecular forms on stimulated T cells.

1983 • 181 citations

The interaction of fibronectin fragments with fibroblastic cells.

1985 • 168 citations

The very late antigen family of heterodimers is part of a superfamily of molecules involved in adhesion and embryogenesis.

1987 • 164 citations

Integrin (the CSAT antigen): functionality requires oligomeric integrity.

1986 • 160 citations

Biochemical characterization of VLA-1 and VLA-2. Cell surface heterodimers on activated T cells.

1985 • 153 citations

VLA‐1: a T cell surface antigen which defines a novel late stage of human T cell activation

1985 • 151 citations

A monoclonal antibody identifies a glycoprotein complex involved in cell-substratum adhesion

1985 • 136 citations

Coupled expression and colocalization of 140K cell adhesion molecules, fibronectin, and laminin during morphogenesis and cytodifferentiation of chick lung cells.

1986 • 135 citations

Immunochemical and amino-terminal sequence comparison of two cytoadhesins indicates they contain similar or identical beta subunits and distinct alpha subunits.

1987 • 131 citations

Membrane glycoproteins involved in cell--substratum adhesion.

1981 • 129 citations

Regulation of fibronectin receptor distribution by transformation, exogenous fibronectin, and synthetic peptides.

1986 • 128 citations

Molecular Interactions in Adherens-Type Contacts

1987 • 122 citations

cDNA sequences from the alpha subunit of the fibronectin receptor predict a transmembrane domain and a short cytoplasmic peptide.

1986 • 115 citations

Substratum contacts and cytoskeletal reorganization of BALB/c 3T3 cells on a cell-binding fragment and heparin-binding fragments of plasma fibronectin

1986 • 111 citations

Characterization of a membrane‐associated glycoprotein complex implicated in cell adhesion to fibronectin

1985 • 97 citations

The fibronectin cell attachment sequence Arg-Gly-Asp-Ser promotes focal contact formation during early fibroblast attachment and spreading.

1987 • 96 citations

Studies on the function of cell surface glycoproteins. I. Use of antisera to surface membranes in the identification of membrane components relevant to cell-substrate adhesion.

1979 • 96 citations

Peptides containing the cell-attachment recognition signal Arg-Gly-Asp prevent gastrulation in Drosophila embryos

1987 • 88 citations

Immunocytochemical localization of 140 kD cell adhesion molecules in cultured chicken fibroblasts, and in chicken smooth muscle and intestinal epithelial tissues.

1985 • 84 citations

Sequence homology of the LFA-1 and Mac-1 leukocyte adhesion glycoproteins and unexpected relation to leukocyte interferon

1985 • 80 citations

Adhesive multiplicity in the interaction of embryonic fibroblasts and myoblasts with extracellular matrices.

1984 • 74 citations

New surface component of fibroblast's focal contacts identified by a monoclonal antibody

1982 • 69 citations

The Drosophila position-specific antigens are a family of cell surface glycoprotein complexes.

1984 • 65 citations

An integral glycoprotein associated with the membrane attachment sites of actin microfilaments.

1985 • 63 citations

Tissue-specific modulation of a set of related cell surface antigens in Drosophila

1985 • 41 citations

Cell biology: The fibronectin receptor family

1986 • 34 citations

CSAT Antibody Interferes with in Vivo Migration of Somitic Myoblast Precursors into the Body Wall

1986 • 6 citations

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Integrin, A Transmembrane Glycoprotein Complex Mediating Cell-Substratum Adhesion (1987) – Journal of Cell Science | Metascience Observatory Explorer