A Rho-related GTPase Is Involved in Ca2+-dependent Neurotransmitter Exocytosis

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Rho GTPases and the Actin Cytoskeleton

1998 • 6,129 citations

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1992 • 4,454 citations

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1992 • 3,628 citations

The synaptic vesicle cycle: a cascade of protein–protein interactions

1995 • 2,004 citations

Phosphorylation and Activation of Myosin by Rho-associated Kinase (Rho-kinase)

1996 • 1,964 citations

Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation.

1983 • 1,162 citations

Glucosylation of Rho proteins by Clostridium difficile toxin B

1995 • 1,025 citations

Thrombin receptor ligation and activated rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets

1995 • 665 citations

High-frequency firing helps replenish the readily releasable pool of synaptic vesicles

1998 • 613 citations

rac, a novel ras-related family of proteins that are botulinum toxin substrates

1989 • 585 citations

Rac and Cdc42 Induce Actin Polymerization and G1 Cell Cycle Progression Independently of p65PAK and the JNK/SAPK MAP Kinase Cascade

1996 • 571 citations

Asparagine residue in the rho Gene Product Is the Modification Site for Botulinum ADP-ribosyltransferase

1989 • 550 citations

Gln 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1

1997 • 531 citations

Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine

1997 • 492 citations

Kinetics and regulation of fast endocytosis at hippocampal synapses

1998 • 422 citations

Synaptic vesicle biogenesis, docking, and fusion: a molecular description

1996 • 349 citations

An analysis of facilitation of transmitter release at the neuromuscular junction of the frog

1967 • 302 citations

Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin

1996 • 290 citations

Rho family GTPases: the cytoskeleton and beyond

1996 • 262 citations

RAB3 AND SYNAPTOTAGMIN: The Yin and Yang of Synaptic Membrane Fusion

1998 • 260 citations

Bilateral Symmetry and Interneuronal Organization in the Buccal Ganglia of Aplysia

1971 • 214 citations

Ras, Rap, and Rac Small GTP-binding Proteins Are Targets for Clostridium sordellii Lethal Toxin Glucosylation

1996 • 206 citations

Rho family small GTP-binding proteins in growth cone signalling

1997 • 190 citations

Inactivation of Ras by Clostridium sordellii Lethal Toxin-catalyzed Glucosylation

1996 • 190 citations

Rac GTPase interacts specifically with phosphatidylinositol 3-kinase

1996 • 186 citations

GENETICS OF SYNAPTIC VESICLE FUNCTION: Toward the Complete Functional Anatomy of an Organelle

1999 • 183 citations

Rho proteins: Targets for bacterial toxins

1997 • 172 citations

Purification and characterization of an ADP-ribosyltransferase produced by Clostridium limosum.

1992 • 169 citations

A novel partner for the GTP‐bound forms of rho and rac

1995 • 166 citations

Myosin II is involved in transmitter release at synapses formed between rat sympathetic neurons in culture

1994 • 154 citations

Purification and characterization of Clostridium sordellii lethal toxin and cross-reactivity with Clostridium difficile cytotoxin

1987 • 142 citations

Molecular localization of the Escherichia coli cytotoxic necrotizing factor CNF1 cell‐binding and catalytic domains

1997 • 137 citations

Hrs-2 is an ATPase implicated in calcium-regulated secretion

1997 • 120 citations

Inhibition of FcεRI-mediated Activation of Rat Basophilic Leukemia Cells by Clostridium difficile Toxin B (Monoglucosyltransferase)

1996 • 117 citations

Association of rap1 and rap2 proteins with the specific granules of human neutrophils. Translocation to the plasma membrane during cell activation.

1992 • 106 citations

Escherichia coli Cytotoxic Necrotizing Factor 1 (CNF1), a Toxin That Activates the Rho GTPase

1997 • 96 citations

Regulation of inositol lipid kinases by Rho and Rac

1998 • 90 citations

Induction of Exocytosis from Permeabilized Mast Cells by the Guanosine Triphosphatases Rac and Cdc42

1998 • 89 citations

Identification of a Potential Effector Pathway for the Trimeric Go Protein Associated with Secretory Granules

1998 • 88 citations

Evidence for Differential Roles of the Rho Subfamily of GTP-Binding Proteins in Glucose- and Calcium-Induced Insulin Secretion from Pancreatic β Cells

1997 • 85 citations

botR/A is a positive regulator of botulinum neurotoxin and associated non‐toxin protein genes in Clostridium botulinum A

1998 • 83 citations

The molecular machinery for fast and slow neurosecretion

1994 • 82 citations

Tissue and Subcellular Distributions of the smg-21/rap1/ Krev-1 Proteins Which Are Partly Distinct from Those of c-ras p21s

1990 • 77 citations

Common mechanisms for regulated exocytosis in the chromaffin cell and the synapse

1997 • 71 citations

A family of ras-like GTP-binding proteins expressed in electromotor neurons

1991 • 67 citations

Trimeric G Proteins Control Exocytosis in Chromaffin Cells

1997 • 64 citations

The Ras Guanine Nucleotide Exchange Factor CDC25Mm Is Present at the Synaptic Junction

1997 • 63 citations

Synaptic vesicle docking and fusion

1999 • 56 citations

Evidence for a functional link between Rab3 and the SNARE complex

1996 • 55 citations

Characterization of the C3 gene of Clostridium botulinum types C and D and its expression in Escherichia coli

1991 • 51 citations

Rac1, a low‐molecular‐mass GTP‐binding‐protein with high intrinsic GTPase activity and distinct biochemical properties

1992 • 50 citations

VAMP (synaptobrevin) is present in the plasma membrane of nerve terminals

1999 • 49 citations

Neurotransmitter release: Variations on a theme

1998 • 48 citations

Association of three small GTP‐binding proteins with cholinergic synaptic vesicles

1993 • 48 citations

β-Adrenergic-induced cytosolic redistribution of Rap1 in rat parotid acini: role in secretion

1998 • 42 citations

Identification of rho as a substrate for botulinum toxin C₃‐catalyzed ADP‐ribosylation

1989 • 41 citations

Calcium-Dependent Regulation of Rab3 in Short-Term Plasticity

1998 • 35 citations

Rho proteins are localized with different membrane compartments involved in vesicular trafficking in anterior pituitary cells

1996 • 30 citations

Rabphilin-3A binds to a Mr 115,000 polypeptide in a phosphatidylserine- and Ca2+-dependent manner

1995 • 19 citations

Identification and localization of low-molecular-mass GTP-binding proteins associated with synaptic vesicles and other membranes

1990 • 14 citations