Memory cell generation ablated by soluble protein antigen by means of effects on T- and B-lymphocyte compartments.

SRα Promoter: an Efficient and Versatile Mammalian cDNA Expression System Composed of the Simian Virus 40 Early Promoter and the R-U5 Segment of Human T-Cell Leukemia Virus Type 1 Long Terminal Repeat

1988 • 1,351 citations

Intraclonal generation of antibody mutants in germinal centres

1991 • 1,083 citations

Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

1989 • 1,015 citations

Maturation of the immune response in germinal centers

1991 • 904 citations

Biological Activity of Recombinant Human Interleukin-2 Produced in Escherichia coli

1984 • 600 citations

The molecular and cellular basis of affinity maturation in the antibody response

1992 • 278 citations

Isolation and characterization of lymphokine cDNA clones encoding mouse and human IgA-enhancing factor and eosinophil colony-stimulating factor activities: relationship to interleukin 5.

1987 • 236 citations

Analysis of somatic mutation and class switching in naive and memory B cells generating adoptive primary and secondary responses

1987 • 230 citations

The separation of different cell classes from lymphoid organs. IX. A simple and rapid method for removal of damaged cells from lymphoid cell suspensions

1973 • 209 citations

Cellular Sites of Immunologic Unresponsiveness

1970 • 202 citations

The Evolution of B-Cell Clones

1990 • 185 citations

Molecular characterization of single memory B cells

1991 • 163 citations

The Need for Central and Peripheral Tolerance in the B Cell Repertoire

1990 • 154 citations

Heterogeneity in Lymphokine Profiles of CD4⁺ and CD8⁺ T Cells and Clones Activated in vivo and in vitro

1991 • 132 citations

T Cell‐Dependent Suppression of an Anti‐Hapten Antibody Response

1975 • 100 citations

Specific inhibition of antibody production. I. Protein-over loading paralysis.

1962 • 99 citations

Frequency analysis of lymphokine-secreting CD4+ and CD8+ T cells activated in a graft-versus-host reaction.

1990 • 90 citations

Tolerance susceptibility of newly generating memory B cells.

1991 • 88 citations

Single cell studies on the antibody-forming potential of fractionated, hapten-specific B lymphocytes.

1976 • 87 citations

A Transgenic Approach to the Study of Peripheral T‐Cell Tolerance

1991 • 54 citations

Analysis of true anti-hapten cytotoxic clones in limit dilution microcultures after correction for "anti-self" activity: precursor frequencies, Ly-2 and Thy-1 phenotype, specificity, and statistical methods.

1983 • 47 citations

SUPPRESSOR CELLS IN TRANSPLANTATION TOLERANCE

1982 • 46 citations

Combinations of interleukins 2, 4 and 5 regulate the secretion of murine immunoglobulin isotypes

1989 • 45 citations

Soluble antigen abrogates the appearance of anti-protein IgG1-forming cell precursors during primary immunization.

1990 • 43 citations

A high-efficiency cloning system for single hapten-specific B lymphocytes that is suitable for assay of putative growth and differentiation factors.

1985 • 34 citations

Effect of Immunological Unresponsiveness on Different Cell Populations

1972 • 34 citations

Molecular and cellular aspects of immunologic tolerance

1991 • 27 citations

A role for suppressor T cells in induction of self-tolerance.

1985 • 25 citations

Sudden appearance of anti-protein IgG1-forming cell precursors early during primary immunization.

1989 • 23 citations

Functional clonal deletion and suppression as complementary mechanisms operative in adult hapten-induced cytotoxic T cell tolerance.

1983 • 19 citations

Transgenic Mice as an in vivo Model for Self‐Reactivity

1990 • 16 citations

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