Mechanism of Ruminant Placental Lactogen Action: Molecular and in Vivo Studies

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Human Growth Hormone and Extracellular Domain of Its Receptor: Crystal Structure of the Complex

1992 • 2,236 citations

Prolactin (PRL) and Its Receptor: Actions, Signal Transduction Pathways and Phenotypes Observed in PRL Receptor Knockout Mice

1998 • 1,846 citations

Growth hormone receptor and serum binding protein: purification, cloning and expression

1987 • 1,540 citations

Dimerization of the Extracellular Domain of the Human Growth Hormone Receptor by a Single Hormone Molecule

1991 • 879 citations

The Prolactin/Growth Hormone Receptor Family

1991 • 795 citations

Signaling by the cytokine receptor superfamily: JAKs and STATs

1994 • 659 citations

Comparison of a Structural and a Functional Epitope

1993 • 512 citations

Prolactin (PRL) and Its Receptor: Actions, Signal Transduction Pathways and Phenotypes Observed in PRL Receptor Knockout Mice

1998 • 473 citations

The X-ray structure of a growth hormone–prolactin receptor complex

1994 • 390 citations

HEMATOPOIETIC RECEPTOR COMPLEXES

1996 • 298 citations

Affinity Maturation of Human Growth Hormone by Monovalent Phage Display

1993 • 227 citations

Variation Among Species in the Endocrine Control of Mammary Growth and Function: The Roles of Prolactin, Growth Hormone, and Placental Lactogen

1986 • 197 citations

Effects of Recombinant Ovine Interferon Tau, Placental Lactogen, and Growth Hormone on the Ovine Uterus1

1999 • 144 citations

OVINE PLACENTAL LACTOGEN INDUCES SOMATOMEDIN: A POSSIBLE ROLE IN FETAL GROWTH

1977 • 140 citations

The Purification and Characterization of Ovine Placental Lactogen

1976 • 115 citations

Real-time Kinetic Measurements of the Interactions between Lactogenic Hormones and Prolactin-Receptor Extracellular Domains from Several Species Support the Model of Hormone-induced Transient Receptor Dimerization

1996 • 111 citations

Placental-fetal hormonal interactions: impact on fetal growth

1995 • 106 citations

Growth Hormone Binding Affinity for Its Receptor Surpasses the Requirements for Cellular Activity

1998 • 103 citations

Structure and Function of Human Growth Hormone: Implications for the Hematopoietins

1993 • 100 citations

Comparison of the intermediate complexes of human growth hormone bound to the human growth hormone and prolactin receptors

1994 • 94 citations

Ternary complex between placental lactogen and the extracellular domain of the prolactin receptor.

2000 • 87 citations

Ruminant placental lactogens: structure and biology

1992 • 77 citations

The growth hormone/prolactin gene family in ruminant placentae.

1995 • 74 citations

Cytokine receptor signalling through two novel families of transducer molecules: Janus kinases, and signal transducers and activators of transcription

1995 • 70 citations

Cloning and Expression of Ovine Placental Lactogen

1989 • 67 citations

Placental Lactogen and Somatotropin: Hormone Binding to the Corpus Luteum and Effects on the Growth and Functions of the Ovary in Heifers1

1994 • 64 citations

Functional Heterodimerization of Prolactin and Growth Hormone Receptors by Ovine Placental Lactogen

2000 • 63 citations

Purification of a lactogenic hormone in sheep placenta

1975 • 63 citations

Purification and Characterization of Bovine Placental Lactogen*

1982 • 62 citations

Ligand-specific dimerization of the extracellular domain of the bovine growth hormone receptor.

1993 • 56 citations

Stimulation of mammogenesis and lactogenesis by recombinant bovine placental lactogen in steroid-primed dairy heifers

1994 • 56 citations

OVINE PLACENTAL LACTOGEN, BUT NOT GROWTH HORMONE, STIMULATES AMINO ACID TRANSPORT IN FETAL RAT DIAPHRAGM

1983 • 52 citations

Isolation and structural characterization of ovine placental lactogen

1977 • 51 citations

Ovine placental lactogen stimulates glycogen synthesis in fetal rat hepatocytes

1984 • 50 citations

Characterization of Glycosylated Bovine Placental Lactogen and the Effect of Enzymatic Deglycosylation on Receptor Binding and Biological Activity

1990 • 49 citations

Preparation of the extracellular domain of the rabbit prolactin receptor expressed in Escherichia coli and its interaction with lactogenic hormones.

1994 • 47 citations

Purification and structural characterization of ovine placental lactogen

1990 • 44 citations

Differing requirements for capacitation in vitro of mouse spermatozoa from two strains

1977 • 44 citations

Preparation, purification, and determination of the biological activities of 12 N terminus-truncated recombinant analogues of bovine placental lactogen.

1992 • 42 citations

Expression of the extracellular domain of the rat liver prolactin receptor and its interaction with ovine prolactin.

1993 • 39 citations

Large-scale preparation and characterization of recombinant ovine placental lactogen

1997 • 39 citations

Characterization of ovine growth hormone (oGH) and ovine placental lactogen (oPL) binding to fetal and adult hepatic tissue in sheep: evidence that oGH and oPL interact with a common receptor.

1994 • 39 citations

Ruminant Placental Lactogens Act as Antagonists to Homologous Growth Hormone Receptors and as Agonists to Human or Rabbit Growth Hormone Receptors

1999 • 39 citations

Crystals of Human Growth Hormone-Receptor Complexes

1993 • 38 citations

Purification of a distinct placental lactogen receptor, a new member of the growth hormone/prolactin receptor family.

1989 • 36 citations

Purification, partial characterization, and development of a specific radioimmunoassay for goat placental lactogen

1990 • 34 citations

Preparation and characterization of recombinant prolactin receptor extracellular domain from rat

1995 • 34 citations

Bovine Placental Lactogen Is a Potent Stimulator of Growth and Displays Strong Binding to Hepatic Receptor Sites of Coho Salmon

1994 • 32 citations

Stimulation of body weight gain of the mature female rat by bovine GH and bovine placental lactogen

1991 • 30 citations

Enhanced heterologous gene expression in novel rpoH mutants of Escherichia coli

1992 • 30 citations

Demonstration of in vivo mammogenic and lactogenic effects of recombinant ovine placental lactogen and mammogenic effect of recombinant ovine GH in ewes during artificial induction of lactation

1999 • 29 citations

Extracellular domain of prolactin receptor from bovine mammary gland: expression in Escherichia coli, purification and characterization of its interaction with lactogenic hormones

1995 • 27 citations

Interaction of lactogenic hormones with purified recombinant extracellular domain of rabbit prolactin receptor expressed in insect cells

1993 • 27 citations

Novel Recombinant Analogues of Bovine Placental Lactogen

1998 • 24 citations

Comparative Study of in Vitro and in Vivo Modulation of Lactogenic and Somatotropic Receptors by Native Human Growth Hormone and Its Modified Analog Prepared by Recombinant Deoxyribonucleic Acid Technology

1987 • 23 citations

Site-Directed Mutations of Human Growth Hormone that Selectively Modify Its Lactogenic Activity and Binding Properties

1990 • 23 citations

Cloning, preparation and characterization of biologically active recombinant caprine placental lactogen

1998 • 22 citations

Differential effects of maternal ovine placental lactogen and growth hormone (GH) administration on GH receptor, insulin-like growth factor (IGF)-1 and IGF binding protein-3 gene expression in the pregnant and fetal sheep.

1996 • 22 citations

Ovine placental lactogen is a potent somatogen in the growth hormone (GH)-deficient rat: comparison of somatogenic activity with bovine GH.

1992 • 22 citations

Comparative Effects of Recombinant Ovine Placental Lactogen and Bovine Growth Hormone on Galactopoiesis in Ewes

1997 • 21 citations

Effects of recombinant ovine placental lactogen and recombinant ovine growth hormone on growth of lambs and milk production of ewes

2001 • 19 citations

Recombinant Prolactin Receptor Extracellular Domain of Rainbow Trout (Oncorhynchus mykiss): Subcloning, Preparation, and Characterization

2000 • 18 citations

Growth-promoting effects of ovine placental lactogen (oPL) in young lambs: comparison with bovine growth hormone provides evidence for a distinct effect of oPL on food intake.

1996 • 18 citations

Biological activity of bovine placental lactogen in 3T3‐F442A preadipocytes is mediated through a somatogenic receptor

1992 • 17 citations

Characterization of ovine growth hormone (oGH) and ovine placental lactogen (oPL) binding to fetal and adult hepatic tissue in sheep: evidence that oGH and oPL interact with a common receptor

1994 • 16 citations

N-terminal-truncated recombinant analogs of bovine placental lactogen: interaction with human and rat growth hormone receptors and insulin-like growth factor-I secretion mediated by somatogenic receptors in rat hepatocytes.

1995 • 15 citations

Ovine placental lactogen lacks direct somatogenic and anticatabolic actions in the postnatal lamb

1995 • 14 citations

The purification and characterization of rabbit placental lactogen

1976 • 14 citations

Site-Directed Mutagenesis of Recombinant Bovine Placental Lactogen at Lysine-73 Leads to Selective Attenuation of Its Somatogenic Activity*

1997 • 14 citations

The effects of ovine placental lactogen and bovine growth hormone on hepatic and mammary gene expression in lactating sheep

1998 • 13 citations

Performance, clinical chemistry, and carcass responses of finishing lambs to recombinant bovine somatotropin and bovine placental lactogen

1993 • 13 citations

Large-Scale Preparation of Recombinant Ovine Prolactin and Determination of Its in Vitro and in Vivo Activity

2001 • 13 citations

Ovine chorionic somatomammotropin and foetal growth

1988 • 11 citations

Selective Modification of Recombinant Bovine Placental Lactogen by Site-directed Mutagenesis at Its C Terminus

1996 • 11 citations

Selective modification at the N-terminal region of human growth hormone that shows antagonistic activity

1997 • 11 citations

IGFBP-2 expression in liver and mammary tissue in lactating and pregnant ewes

1993 • 11 citations

Maintenance of Receptors for Luteinizing Hormone by Ovine Placental Lactogen in Pseudopregnant Rats1

1980 • 10 citations

Mutations of ovine and bovine placental lactogens change, in different ways, the biological activity mediated through homologous and heterologous lactogenic receptors

2001 • 10 citations

Ovine placental lactogen is a potent somatogen in the growth hormone (GH)-deficient rat: comparison of somatogenic activity with bovine GH

1992 • 9 citations

Recombinant Extracellular Domain of Rabbit Growth Hormone Receptor (rbGHR-ECD): Preparation and use for Comparing Binding Capacity and Biological Activity of Somatogenic Hormones

2000 • 9 citations

Inhibitory effect of ovine and human placental lactogens on progesterone catabolism in luteinized rat ovaries in vitro.

1983 • 8 citations

Placental lactogen not growth hormone and prolactin regulates secretion of progesterone in vitro by the 40-45 day ovine corpus luteum of pregnancy.

2000 • 6 citations

Evaluation of the somatogenic activity of bovine placental lactogen with cell lines transfected with the bovine somatotropin receptor

1999 • 5 citations

N-terminal-truncated recombinant analogs of bovine placental lactogen: interaction with human and rat growth hormone receptors and insulin- like growth factor-I secretion mediated by somatogenic receptors in rat hepatocytes

1995 • 5 citations

Site-Directed Mutagenesis of Recombinant Bovine Placental Lactogen at Lysine-73 Leads to Selective Attenuation of Its Somatogenic Activity

1997 • 4 citations

Rapidly reversible binding of rabbit prolactin to the rabbit prolactin receptor accounts for the differences between homologous and heterologous binding

1997 • 3 citations