Functional Heterodimerization of Prolactin and Growth Hormone Receptors by Ovine Placental Lactogen

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Prolactin (PRL) and Its Receptor: Actions, Signal Transduction Pathways and Phenotypes Observed in PRL Receptor Knockout Mice

1998 • 1,846 citations

Immobilization of proteins to a carboxymethyldextran-modified gold surface for biospecific interaction analysis in surface plasmon resonance sensors

1991 • 1,263 citations

Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose

1986 • 1,100 citations

Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

1993 • 988 citations

Signaling Through the Hematopoietic Cytokine Receptors

1995 • 617 citations

Variation Among Species in the Endocrine Control of Mammary Growth and Function: The Roles of Prolactin, Growth Hormone, and Placental Lactogen

1986 • 197 citations

Identification of JAK protein tyrosine kinases as signaling molecules for prolactin. Functional analysis of prolactin receptor and prolactin-erythropoietin receptor chimera expressed in lymphoid cells.

1994 • 159 citations

Differential activation of Stat3 and Stat5 by distinct regions of the growth hormone receptor.

1996 • 126 citations

Antagonistic Properties of Human Prolactin Analogs That Show Paradoxical Agonistic Activity in the Nb2 Bioassay

1996 • 118 citations

The sheep growth hormone receptor: Molecular cloning and ontogeny of mRNA expression in the liver

1990 • 116 citations

The Purification and Characterization of Ovine Placental Lactogen

1976 • 115 citations

The Molecular Basis for Growth Hormone–Receptor Interactions

1993 • 114 citations

A single phosphotyrosine residue of the prolactin receptor is responsible for activation of gene transcription.

1995 • 113 citations

Real-time Kinetic Measurements of the Interactions between Lactogenic Hormones and Prolactin-Receptor Extracellular Domains from Several Species Support the Model of Hormone-induced Transient Receptor Dimerization

1996 • 111 citations

Molecular cloning of the bovine prolactin receptor and distribution of prolactin and growth hormone receptor transcripts in fetal and utero-placental tissues

1992 • 106 citations

Placental-fetal hormonal interactions: impact on fetal growth

1995 • 106 citations

Tissue distribution and ontogeny of growth hormone receptor messenger ribonucleic acid and ligand binding to hepatic tissue in the midgestation sheep fetus.

1993 • 81 citations

Long and short forms of the ovine prolactin receptor: cDNA cloning and genomic analysis reveal that the two forms arise by different alternative splicing mechanisms in ruminants and in rodents

1997 • 76 citations

Cloning and Expression of Ovine Placental Lactogen

1989 • 67 citations

Purification of a lactogenic hormone in sheep placenta

1975 • 63 citations

The Glycogenic Effects of Placental Lactogen and Growth Hormone in Ovine Fetal Liver Are Mediated through Binding to Specific Fetal Ovine Placental Lactogen Receptors*

1986 • 61 citations

Ligand-specific dimerization of the extracellular domain of the bovine growth hormone receptor.

1993 • 56 citations

Isolation and structural characterization of ovine placental lactogen

1977 • 51 citations

Preparation of the extracellular domain of the rabbit prolactin receptor expressed in Escherichia coli and its interaction with lactogenic hormones.

1994 • 47 citations

Chimeric Granulocyte/Macrophage Colony-stimulating Factor/Transforming Growth Factor-β (TGF-β) Receptors Define a Model System for Investigating the Role of Homomeric and Heteromeric Receptors in TGF-β Signaling

1996 • 44 citations

Purification and structural characterization of ovine placental lactogen

1990 • 44 citations

Serum half-life and in-vivo actions of recombinant bovine placental lactogen in the dairy cow

1992 • 43 citations

Bestimmung der Molekulargewichte von neuen Trypsin-Inhibitoren mit Hilfe der Sephadex-Gelfiltration

1965 • 42 citations

Preparation, purification, and determination of the biological activities of 12 N terminus-truncated recombinant analogues of bovine placental lactogen.

1992 • 42 citations

Large-scale preparation and characterization of recombinant ovine placental lactogen

1997 • 39 citations

Ruminant Placental Lactogens Act as Antagonists to Homologous Growth Hormone Receptors and as Agonists to Human or Rabbit Growth Hormone Receptors

1999 • 39 citations

Characterization of ovine growth hormone (oGH) and ovine placental lactogen (oPL) binding to fetal and adult hepatic tissue in sheep: evidence that oGH and oPL interact with a common receptor.

1994 • 39 citations

Purification of a distinct placental lactogen receptor, a new member of the growth hormone/prolactin receptor family.

1989 • 36 citations

Preparation and characterization of recombinant prolactin receptor extracellular domain from rat

1995 • 34 citations

Bovine Placental Lactogen Is a Potent Stimulator of Growth and Displays Strong Binding to Hepatic Receptor Sites of Coho Salmon

1994 • 32 citations

Beta-galactosidase and chloramphenicol acetyltransferase assays in 96-well plates.

1993 • 31 citations

Stimulation of body weight gain of the mature female rat by bovine GH and bovine placental lactogen

1991 • 30 citations

Demonstration of in vivo mammogenic and lactogenic effects of recombinant ovine placental lactogen and mammogenic effect of recombinant ovine GH in ewes during artificial induction of lactation

1999 • 29 citations

Extracellular domain of prolactin receptor from bovine mammary gland: expression in Escherichia coli, purification and characterization of its interaction with lactogenic hormones

1995 • 27 citations

PURIFICATION AND SOME PROPERTIES OF OVINE PLACENTAL LACTOGEN

1978 • 27 citations

OVINE PLACENTAL LACTOGEN STIMULATES AMINO ACID TRANSPORT IN. RAT DIAPHRAGM

1982 • 27 citations

Lactogenic Effect of Bovine Placental Lactogen on Pregnant Rabbit but not Pregnant Heifer Mammary Gland Explants

1986 • 27 citations

Novel Recombinant Analogues of Bovine Placental Lactogen

1998 • 24 citations

Differential effects of maternal ovine placental lactogen and growth hormone (GH) administration on GH receptor, insulin-like growth factor (IGF)-1 and IGF binding protein-3 gene expression in the pregnant and fetal sheep.

1996 • 22 citations

Ovine placental lactogen is a potent somatogen in the growth hormone (GH)-deficient rat: comparison of somatogenic activity with bovine GH.

1992 • 22 citations

Cloning, preparation and characterization of biologically active recombinant caprine placental lactogen

1998 • 22 citations

Nutritional Regulation of the Placental Lactogen Receptor in Fetal Liver: Implications for Fetal Metabolism and Growth*

1989 • 20 citations

Growth-promoting effects of ovine placental lactogen (oPL) in young lambs: comparison with bovine growth hormone provides evidence for a distinct effect of oPL on food intake.

1996 • 18 citations

N-terminal-truncated recombinant analogs of bovine placental lactogen: interaction with human and rat growth hormone receptors and insulin-like growth factor-I secretion mediated by somatogenic receptors in rat hepatocytes.

1995 • 15 citations

Ovine placental lactogen lacks direct somatogenic and anticatabolic actions in the postnatal lamb

1995 • 14 citations

Site-Directed Mutagenesis of Recombinant Bovine Placental Lactogen at Lysine-73 Leads to Selective Attenuation of Its Somatogenic Activity*

1997 • 14 citations

Structural and Functional Epitopes in the Growth Hormone Receptor Complex

1995 • 13 citations

Selective Modification of Recombinant Bovine Placental Lactogen by Site-directed Mutagenesis at Its C Terminus

1996 • 11 citations

Selective modification at the N-terminal region of human growth hormone that shows antagonistic activity

1997 • 11 citations

Pneumocystis carinii Modulates Cyclin‐Dependant Kinase Activity in a Lung Epithelial Cell Line

1996 • 5 citations