Site-Directed Mutations of Human Growth Hormone that Selectively Modify Its Lactogenic Activity and Binding Properties

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

High-Resolution Epitope Mapping of hGH-Receptor Interactions by Alanine-Scanning Mutagenesis

1989 • 1,357 citations

Insulin-Dependent Regulation of Insulin Receptor Concentrations: A Direct Demonstration in Cell Culture

1974 • 1,037 citations

A dual effector theory of growth-hormone action

1985 • 512 citations

Three-dimensional structure of a genetically engineered variant of porcine growth hormone.

1987 • 457 citations

Mode of Action of Pituitary Growth Hormone on Target Cells

1985 • 452 citations

Structural Features of Prolactins and Growth Hormones That Can Be Related to Their Biological Properties*

1986 • 350 citations

Receptor and Antibody Epitopes in Human Growth Hormone Identified by Homolog-Scanning Mutagenesis

1989 • 345 citations

Human Growth Hormone: A Complex of Proteins

1980 • 201 citations

The Isolation of Pituitary Growth Hormone

1944 • 157 citations

Binding sites of human growth hormone and ovine and bovine prolactins in the mammary gland and the liver of lactating dairy cow

1984 • 87 citations

Enhancement of Human Growth Hormone-Stimulated Mitogenesis of Nb₂Node Lymphoma Cells by 12-O-Tetradecanoyl-Phorbol-13-Acetate*

1985 • 86 citations

Human growth hormone but not ovine or bovine growth hormones exhibits galactopoietic prolactin-like activity in organ culture from bovine lactating mammary gland

1983 • 77 citations

LACTOGENIC AND PIGEON CROP-STIMULATING ACTIVITIES OF HUMAN PITUITARY GROWTH HORMONE PREPARATIONS

1965 • 76 citations

Prolactin and Growth Hormone: Specialists on One Hand and Mutual Mimics on the Other

1982 • 74 citations

Biosynthetic 20-kilodalton methionyl-human growth hormone has diabetogenic and insulin-like activities.

1985 • 55 citations

Biological Activity of Bacterial Derived Human Growth Hormone in Adipose Tissue of Hypophysectomized Rats*

1984 • 49 citations

Inhibition of Lactogenic Activities of Ovine Prolactin and Human Growth Hormone (hGH) by a Novel Form of a Modified Recombinant hGH*

1986 • 44 citations

The Acute Effects of Growth Hormone on Amino Acid Transport and Protein Synthesis Are Due to Its Insulin-Like Action*

1988 • 44 citations

Hormonal control of casein synthesis in organ culture of the bovine lactating mammary gland

1982 • 42 citations

Human pituitary growth hormone

1964 • 40 citations

Bioactive Recombinant Methionyl Bovine Prolactin: Structure-Function Studies Using Site-Specific Mutagenesis

1989 • 39 citations

Characterization of lactogen receptors in lactogenic hormone‐dependent and independent NB2 lymphoma cell lines

1987 • 27 citations

Comparative Study of in Vitro and in Vivo Modulation of Lactogenic and Somatotropic Receptors by Native Human Growth Hormone and Its Modified Analog Prepared by Recombinant Deoxyribonucleic Acid Technology

1987 • 23 citations

A Mutant Lactogenic Hormone Binds, but Does not Activate, the Prolactin Receptor

1989 • 23 citations

Nonmammalian Growth Hormones Have Diabetogenic and Insulin-Like Activities*

1985 • 17 citations

Chimeric Bovine-Human Growth Hormone Prepared by Recombinant DNA Technology: Binding Properties and Biological Activity

1989 • 15 citations

Covalent coupling of bovine growth hormone to its receptor in bovine liver membranes

1987 • 13 citations

The quantitation of human growth hormone by a radioreceptor assay using an established human cell line

1987 • 10 citations

Indication of different lactogen and somatogen binding sites in the human growth hormone molecule as probed with monoclonal antibodies

1989 • 8 citations