Recombinant Extracellular Domain of Rabbit Growth Hormone Receptor (rbGHR-ECD): Preparation and use for Comparing Binding Capacity and Biological Activity of Somatogenic Hormones

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Human Growth Hormone and Extracellular Domain of Its Receptor: Crystal Structure of the Complex

1992 • 2,236 citations

Prolactin (PRL) and Its Receptor: Actions, Signal Transduction Pathways and Phenotypes Observed in PRL Receptor Knockout Mice

1998 • 1,846 citations

Growth hormone receptor and serum binding protein: purification, cloning and expression

1987 • 1,540 citations

Dimerization of the Extracellular Domain of the Human Growth Hormone Receptor by a Single Hormone Molecule

1991 • 879 citations

The Prolactin/Growth Hormone Receptor Family

1991 • 795 citations

Signaling by the cytokine receptor superfamily: JAKs and STATs

1994 • 659 citations

Protein volumes and hydration effects. The calculations of partial specific volumes, neutron scattering matchpoints and 280-nm absorption coefficients for proteins and glycoproteins from amino acid sequences

1986 • 575 citations

Comparison of a Structural and a Functional Epitope

1993 • 512 citations

The X-ray structure of a growth hormone–prolactin receptor complex

1994 • 390 citations

HEMATOPOIETIC RECEPTOR COMPLEXES

1996 • 298 citations

Affinity Maturation of Human Growth Hormone by Monovalent Phage Display

1993 • 227 citations

Real-time Kinetic Measurements of the Interactions between Lactogenic Hormones and Prolactin-Receptor Extracellular Domains from Several Species Support the Model of Hormone-induced Transient Receptor Dimerization

1996 • 111 citations

Receptor dimerization determines the effects of growth hormone in primary rat adipocytes and cultured human IM-9 lymphocytes.

1994 • 107 citations

Structure and Function of Human Growth Hormone: Implications for the Hematopoietins

1993 • 100 citations

Comparison of the intermediate complexes of human growth hormone bound to the human growth hormone and prolactin receptors

1994 • 94 citations

Binding sites of human growth hormone and ovine and bovine prolactins in the mammary gland and the liver of lactating dairy cow

1984 • 87 citations

Enhancement of Human Growth Hormone-Stimulated Mitogenesis of Nb₂Node Lymphoma Cells by 12-O-Tetradecanoyl-Phorbol-13-Acetate*

1985 • 86 citations

Cytokine receptor signalling through two novel families of transducer molecules: Janus kinases, and signal transducers and activators of transcription

1995 • 70 citations

Ligand-specific dimerization of the extracellular domain of the bovine growth hormone receptor.

1993 • 56 citations

Logical analysis of timing-dependent receptor signalling specificity: application to the insulin receptor metabolic and mitogenic signalling pathways

1997 • 49 citations

Identification and characterization of growth hormone receptor mRNA in the mammary gland

1991 • 48 citations

Preparation of the extracellular domain of the rabbit prolactin receptor expressed in Escherichia coli and its interaction with lactogenic hormones.

1994 • 47 citations

A Growth Hormone Agonist Produced by Targeted Mutagenesis at Binding Site 1.

1995 • 43 citations

Expression of the extracellular domain of the rat liver prolactin receptor and its interaction with ovine prolactin.

1993 • 39 citations

Large-scale preparation and characterization of recombinant ovine placental lactogen

1997 • 39 citations

Ruminant Placental Lactogens Act as Antagonists to Homologous Growth Hormone Receptors and as Agonists to Human or Rabbit Growth Hormone Receptors

1999 • 39 citations

Recombinant Carp (Cyprinus carpio) Growth Hormone: Expression, Purification, and Determination of Biological Activity in Vitro and in Vivo

1993 • 39 citations

Crystals of Human Growth Hormone-Receptor Complexes

1993 • 38 citations

Preparation and characterization of recombinant prolactin receptor extracellular domain from rat

1995 • 34 citations

Enhanced heterologous gene expression in novel rpoH mutants of Escherichia coli

1992 • 30 citations

Extracellular domain of prolactin receptor from bovine mammary gland: expression in Escherichia coli, purification and characterization of its interaction with lactogenic hormones

1995 • 27 citations

Interaction of lactogenic hormones with purified recombinant extracellular domain of rabbit prolactin receptor expressed in insect cells

1993 • 27 citations

Novel Recombinant Analogues of Bovine Placental Lactogen

1998 • 24 citations

Cloning, preparation and characterization of biologically active recombinant caprine placental lactogen

1998 • 22 citations

Crystallization of ovine placental lactogen in a 1:2 complex with the extracellular domain of the rat prolactin receptor

1998 • 16 citations

Site-Directed Mutagenesis of Recombinant Bovine Placental Lactogen at Lysine-73 Leads to Selective Attenuation of Its Somatogenic Activity*

1997 • 14 citations

Selective modification at the N-terminal region of human growth hormone that shows antagonistic activity

1997 • 11 citations

Recombinant analogues of prolactin, growth hormone, and placental lactogen: correlations between physical structure, binding characteristics, and activity.

1997 • 11 citations