Polo kinase: the choreographer of the mitotic stage?

A 20s complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B

1995 • 964 citations

Cyclin‐dependent protein kinases: Key regulators of the eukaryotic cell cycle

1995 • 918 citations

Relationship of actin and tubulin distribution to bud growth in wild-type and morphogenetic-mutant Saccharomyces cerevisiae.

1984 • 838 citations

GENETIC CONTROL OF THE CELL DIVISION CYCLE IN YEAST: V. GENETIC ANALYSIS OF cdc MUTANTS

1973 • 728 citations

Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes.

1996 • 685 citations

Polo, a mitotic mutant of Drosophila displaying abnormal spindle poles

1988 • 546 citations

Purification and Molecular Cloning of Plx1, a Cdc25-Regulatory Kinase from Xenopus Egg Extracts

1996 • 506 citations

Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function.

1995 • 471 citations

Duplication of Spindle Plaques and Integration of the Yeast Cell Cycle

1974 • 419 citations

polo encodes a protein kinase homolog required for mitosis in Drosophila.

1991 • 403 citations

The conserved Schizosaccharomyces pombe kinase plo1, required to form a bipolar spindle, the actin ring, and septum, can drive septum formation in G1 and G2 cells.

1995 • 376 citations

Induction and down-regulation of PLK, a humanserine/threonine kinase expressed in proliferating cells andtumors.

1994 • 278 citations

Cell cycle analysis and chromosomal localization of human Plk1, a putative homologue of the mitotic kinases Drosophila polo and Saccharomyces cerevisiae Cdc5

1994 • 275 citations

A multicopy suppressor gene of the Saccharomyces cerevisiae G1 cell cycle mutant gene dbf4 encodes a protein kinase and is identified as CDC5.

1993 • 270 citations

Plk Is an M-Phase-Specific Protein Kinase and Interacts with a Kinesin-Like Protein, CHO1/MKLP-1

1995 • 266 citations

Phosphoproteins are components of mitotic microtubule organizing centers.

1984 • 246 citations

Identification by Targeted Differential Display of an Immediate Early Gene Encoding a Putative Serine/Threonine Kinase

1995 • 196 citations

Identification of an Early-Growth-Response Gene Encoding a Novel Putative Protein Kinase

1992 • 187 citations

Polo-like Kinase Is a Cell Cycle-regulated Kinase Activated during Mitosis

1995 • 165 citations

Identification and cloning of a protein kinase-encoding mouse gene, Plk, related to the polo gene of Drosophila.

1993 • 158 citations

prk, a Cytokine-inducible Human Protein Serine/Threonine Kinase Whose Expression Appears to be Down-regulated in Lung Carcinomas

1996 • 148 citations

A conserved mitotic kinase active at late anaphase—telophase in syncytial Drosophila embryos

1993 • 128 citations

Cloning and characterization of human and murine homologues of the Drosophila polo serine-threonine kinase.

1994 • 116 citations

Identification of an early-growth-response gene encoding a novel putative protein kinase.

1992 • 110 citations

Sak, a murine protein-serine/threonine kinase that is related to the Drosophila polo kinase and involved in cell proliferation.

1994 • 100 citations

A dependent pathway of gene functions leading to chromosome segregation in Saccharomyces cerevisiae.

1982 • 92 citations

Cell Cycle- and Terminal Differentiation-Associated Regulation of the Mouse mRNA Encoding a Conserved Mitotic Protein Kinase

1993 • 86 citations

A Multicopy Suppressor Gene of the Saccharomyces cerevisiae G₁ Cell Cycle Mutant Gene dbf4 Encodes a Protein Kinase and Is Identified as CDC5

1993 • 84 citations

The conserved mitotic kinase polo is regulated by phosphorylation and has preferred microtubule-associated substrates in Drosophila embryo extracts.

1996 • 84 citations

DIPLOID SPORE FORMATION AND OTHER MEIOTIC EFFECTS OF TWO CELL-DIVISION-CYCLE MUTATIONS OF SACCHAROMYCES CEREVISIAE

1980 • 53 citations

Cell cycle- and terminal differentiation-associated regulation of the mouse mRNA encoding a conserved mitotic protein kinase.

1993 • 51 citations