Functional proteomics of transforming growth factor-beta1-stimulated Mv1Lu epithelial cells: Rad51 as a target of TGFbeta1-dependent regulation of DNA repair

The Hallmarks of Cancer

2000 • 27,569 citations

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

1996 • 8,994 citations

TGF-β SIGNAL TRANSDUCTION

1998 • 7,582 citations

TGF-β signalling from cell membrane to nucleus through SMAD proteins

1997 • 3,650 citations

Caspases: killer proteases

1997 • 2,440 citations

Two‐dimensional electrophoresis. The current state of two‐dimensional electrophoresis with immobilized pH gradients

1988 • 2,431 citations

The current state of two-dimensional electrophoresis with immobilized pH gradients

2000 • 1,498 citations

Transcriptional Activators of TGF-β Responses: Smads

1998 • 1,024 citations

Smad regulation in TGF-β signal transduction

2001 • 917 citations

Mass spectrometric identification of proteins from silver-stained polyacrylamide gel: A method for the removal of silver ions to enhance sensitivity

1999 • 896 citations

Targeted disruption of the Rad51 gene leads to lethality in embryonic mice.

1996 • 789 citations

Specificity, diversity, and regulation in TGF-beta superfamily signaling.

1999 • 788 citations

Growth Inhibitor from BSC-1 Cells Closely Related to Platelet Type β Transforming Growth Factor

1984 • 779 citations

A Mutation in Mouse rad51 Results in an Early Embryonic Lethal That Is Suppressed by a Mutation in p53

1996 • 692 citations

Sample purification and preparation technique based on nano-scale reversed-phase columns for the sensitive analysis of complex peptide mixtures by matrix-assisted laser desorption/ionization mass spectrometry

1999 • 672 citations

Identification of Novel TGF-β/Smad Gene Targets in Dermal Fibroblasts using a Combined cDNA Microarray/Promoter Transactivation Approach

2001 • 628 citations

TGFβ1 Inhibits the Formation of Benign Skin Tumors, but Enhances Progression to Invasive Spindle Carcinomas in Transgenic Mice

1996 • 619 citations

TGF-β signaling by Smad proteins

2000 • 618 citations

Role of the human RAD51 protein in homologous recombination and double-stranded-break repair

1998 • 550 citations

Role of Transforming Growth Factor-beta Signaling in Cancer

2000 • 525 citations

Genetic programs of epithelial cell plasticity directed by transforming growth factor-β

2001 • 520 citations

TGF-β signaling by Smad proteins

2000 • 406 citations

Functional Characterization of Transforming Growth Factor β Signaling in Smad2- and Smad3-deficient Fibroblasts

2001 • 397 citations

Phosphorylation of Ser465 and Ser467 in the C Terminus of Smad2 Mediates Interaction with Smad4 and Is Required for Transforming Growth Factor-β Signaling

1997 • 383 citations

Nuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damage

1999 • 348 citations

Defective repression of c- myc in breast cancer cells: A loss at the core of the transforming growth factor β growth arrest program

2001 • 320 citations

The Rad51 Paralog Rad51B Promotes Homologous Recombinational Repair

2000 • 263 citations

Identification of Novel MAP Kinase Pathway Signaling Targets by Functional Proteomics and Mass Spectrometry

2000 • 246 citations

Proteome profiling of bladder squamous cell carcinomas: identification of markers that define their degree of differentiation.

1997 • 205 citations

Differential Effects of Transforming Growth Factor-β on the Expression of Collagenase-1 and Collagenase-3 in Human Fibroblasts

1998 • 192 citations

Functional Proteomics Analysis of Signal Transduction Pathways of the Platelet-Derived Growth Factor β Receptor

1999 • 183 citations

Regulation of Smad signaling by protein kinase C

2001 • 179 citations

The Fas-induced Apoptosis Analyzed by High Throughput Proteome Analysis

2000 • 163 citations

Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor beta 1.

1995 • 131 citations

Transforming growth factor beta 1 suppresses genomic instability independent of a G1 arrest, p53, and Rb.

1996 • 115 citations

Genes dependent on zebrafishcyclops function identified by AFLP differential gene expression screen

2000 • 112 citations

Analysis of polypeptide expression in benign and malignant human breast lesions: down-regulation of cytokeratins

1996 • 92 citations

Blockade of Tumor Cell Transforming Growth Factor-βs Enhances Cell Cycle Progression and Sensitizes Human Breast Carcinoma Cells to Cytotoxic Chemotherapy

1998 • 84 citations

An overview of collagenase-3 expression in malignant tumors and analysis of its potential value as a target in antitumor therapies

2000 • 83 citations

Serum and transforming growth factor beta regulate glial fibrillary acidic protein in serum-free-derived mouse embryo cells.

1990 • 76 citations

Sample preparation by SDS/PAGE and in-gel digestion

2000 • 72 citations

A Unique Transactivation Sequence Motif Is Found in the Carboxyl-Terminal Domain of the Single-Strand-Binding Protein FBP

1996 • 70 citations

Transforming growth factor β1 inhibits collagenase 3 expression by transcriptional and post-transcriptional mechanisms in osteoblast cultures

1997 • 59 citations

Targets of Transcriptional Regulation by Transforming Growth Factor‐β: Expression Profile Analysis Using Oligonucleotide Arrays

2001 • 46 citations

Differential expression of keratins 10, 17, and 19 in normal cervical epithelium, cervical intraepithelial neoplasia, and cervical carcinoma

1999 • 43 citations

Regulation of HSP60 mRNA expression in a human ovarian carcinoma cell line

1993 • 32 citations

Transforming growth factor-β1 enhances the lethal effects of DNA-damaging agents in a human lung-cancer cell line

1997 • 30 citations

Delays in malignant tumor development in transgenic mice by forced epidermal keratin 10 expression in mouse skin carcinomas

1997 • 26 citations

The Rad51 Paralog Rad51B Promotes Homologous Recombinational Repair

2000 • 18 citations

Transforming growth factor β1 inhibits collagenase 3 expression by transcriptional and post‐transcriptional mechanisms in osteoblast cultures

1997 • 2 citations

Transforming Growth Factor-βs

1989 • 2 citations

Transforming growth factor‐β1 enhances the lethal effects of DNA‐damaging agents in a human lung‐cancer cell line

1997 • 1 citations