The Rad51 Paralog Rad51B Promotes Homologous Recombinational Repair

XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

1999 • 1,322 citations

Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein

1992 • 1,231 citations

Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells

1998 • 1,202 citations

DMC1: A meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression

1992 • 1,133 citations

Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death

1998 • 793 citations

Integrating Genetic Approaches into the Discovery of Anticancer Drugs

1997 • 757 citations

Homology-directed repair is a major double-strand break repair pathway in mammalian cells

1998 • 628 citations

Stable Interaction between the Products of the BRCA1 and BRCA2 Tumor Suppressor Genes in Mitotic and Meiotic Cells

1998 • 625 citations

Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes.

1995 • 556 citations

Role of the human RAD51 protein in homologous recombination and double-stranded-break repair

1998 • 550 citations

Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by Rad51 recombinase.

1997 • 536 citations

Increased ratio of targeted to random integration after transfection of chicken B cell lines

1991 • 534 citations

XRCC2 and XRCC3, New Human Rad51-Family Members, Promote Chromosome Stability and Protect against DNA Cross-Links and Other Damages

1998 • 530 citations

Molecular mechanisms of DNA double-strand break repair

1998 • 515 citations

Cisplatin and DNA repair in cancer chemotherapy

1995 • 506 citations

hMre11 and hRad50 Nuclear Foci Are Induced During the Normal Cellular Response to DNA Double-Strand Breaks †

1997 • 504 citations

Stable DNA replication: interplay between DNA replication, homologous recombination, and transcription

1997 • 500 citations

Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways.

1996 • 492 citations

Cloning of human, mouse and fission yeast recombination genes homologous to RAD51 and recA

1993 • 486 citations

Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance

1996 • 478 citations

Disruption of Mouse RAD54 Reduces Ionizing Radiation Resistance and Homologous Recombination

1997 • 438 citations

Sister Chromatid Exchanges Are Mediated by Homologous Recombination in Vertebrate Cells

1999 • 427 citations

Catalysis of homologous DNA pairing by yeast Rad51 and Rad54 proteins

1998 • 426 citations

Genetic evidence for involvement of type 1,type 2and type 3inositol 1,4,5-trisphosphate receptors in signal transduction through the B-cell antigen receptor

1997 • 415 citations

DNA recombination: the replication connection

1999 • 411 citations

BRCA2 is required for ionizing radiation-induced assembly of Rad51 complex in vivo.

1999 • 406 citations

Nuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damage

1999 • 348 citations

Semidominant Suppressors of Srs2 Helicase Mutations of Saccharomyces cerevisiae Map in the RAD51 Gene, Whose Sequence Predicts a Protein with Similarities to Procaryotic RecA Proteins

1992 • 328 citations

Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination

1999 • 327 citations

Complex formation in yeast double-strand break repair: participation of Rad51, Rad52, Rad55, and Rad57 proteins.

1995 • 297 citations

Reduced X-Ray Resistance and Homologous Recombination Frequencies in a RAD54 Mutant of the Chicken DT40 Cell Line

1997 • 277 citations

Rad52 associates with RPA and functions with Rad55 and Rad57 to assemble meiotic recombination complexes

1998 • 265 citations

Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene.

1995 • 256 citations

Xrcc3 Is Required for Assembly of Rad51 Complexes in Vivo

1998 • 251 citations

Nucleotide Sequence and Transcriptional Regulation of the Yeast Recombinational Repair Gene RAD51

1992 • 246 citations

Homologous recombination and the roles of double-strand breaks

1995 • 234 citations

Functional Differences and Interactions among the Putative RecA Homologs Rad51, Rad55, and Rad57

1995 • 228 citations

Light chain gene conversion continues at high rate in an ALV-induced cell line.

1990 • 226 citations

Homologous Recombination, but Not DNA Repair, Is Reduced in Vertebrate Cells Deficient in RAD52

1998 • 226 citations

Mouse Rad54 affects DNA conformation and DNA-damage-induced Rad51 foci formation

1999 • 213 citations

The Saccharomyces cerevisiae Ku Autoantigen Homologue Affects Radiosensitivity Only in the Absence of Homologous Recombination

1996 • 189 citations

Isolation and characterization of RAD51C, a new human member of the RAD51 family of related genes

1998 • 177 citations

Disruption of muREC2/RAD51L1 in Mice Results in Early Embryonic Lethality Which Can Be Partially Rescued in a p53^−/− Background

1999 • 166 citations

The Mouse and Human Homologs of DMC1, the Yeast Meiosis-Specific Homologous Recombination Gene, Have a Common Unique form of Exon-Skipped Transcript in Meiosis

1996 • 165 citations

S phase specific formation of the human Rad51 protein nuclear foci in lymphocytes.

1996 • 163 citations

A surfeit of RAD51-like genes?

1999 • 157 citations

The XRCC2 DNA repair gene from human and mouse encodes a novel member of the recA/RAD51 family

1998 • 149 citations

Cross-sensitivity of γ-ray-sensitive hamster mutants to cross-linking agents

1991 • 146 citations

Allelic knockout of novel splice variants of human recombination repair gene RAD51B in t(12;14) uterine leiomyomas.

1999 • 142 citations

Evolutionary Comparisons of RecA-Like Proteins Across All Major Kingdoms of Living Organisms

1997 • 138 citations

Identification, Characterization, and Genetic Mapping ofRad51d,a New Mouse and HumanRAD51/RecA-Related Gene

1998 • 137 citations

Mutations of a novel human RAD54 homologue, RAD54B, in primary cancer

1999 • 135 citations

A broadening view of recombinational DNA repair in bacteria

1998 • 134 citations

The contribution of homologous recombination in preserving genome integrity in mammalian cells

1999 • 132 citations

Identification of a Novel HumanRAD51Homolog,RAD51B

1997 • 128 citations

RecA-like Recombination Proteins in Eukaryotes: Functions and Structures of RAD51 Genes

1993 • 118 citations

Sequence of the RAD55 gene of Saccharomyces cerevisiae: similarity of RAD55 to prokaryotic RecA and other RecA-like proteins

1994 • 108 citations

Isolation of human and mouse genes based on homology to REC2, a recombinational repair gene from the fungus Ustilago maydis

1997 • 93 citations

Multiple Pathways for Repair of DNA Double-Strand Breaks in Mammalian Chromosomes

1999 • 91 citations

Isolation of novel human and mouse genes of the recA/RAD51 recombination-repair gene family

1998 • 85 citations

Mutations in the RAD54 recombination gene in primary cancers

1999 • 77 citations

Chromosome Instability Syndromes: Lessons for Carcinogenesis

1997 • 75 citations

RAG-2 expression is not essential for chicken immunoglobulin gene conversion.

1992 • 61 citations

Genotoxicity of 1-nitronaphthalene in Chinese hamster V79 cells

1991 • 35 citations

In vitro reconstitution of homologous recombination reactions

1994 • 25 citations

Nuclear Rad51 Foci Induced by DNA Damage Are Distinct from Rad51 Foci Associated with B Cell Activation and Recombination

1997 • 22 citations

Sequence analysis and expression of a novel mouse homolog of Escherichia coli recA gene

1998 • 21 citations

Analysis of the Human RAD51L1 Promoter Region and Its Activation by UV Light

1998 • 15 citations

Identification of a Novel HumanRAD51Homolog,RAD51B

1998 • 14 citations