Induction of Protective CTL Responses in Newborn Mice by a Murine Retrovirus

TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties

1989 • 7,558 citations

Tolerance, Danger, and the Extended Family

1994 • 4,654 citations

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy

1995 • 1,695 citations

Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets.

1989 • 1,462 citations

Plaque assay techniques for murine leukemia viruses

1970 • 1,271 citations

Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells

1993 • 1,219 citations

Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo.

1987 • 1,166 citations

Neonatal Tolerance Revisited: Turning on Newborn T Cells with Dendritic Cells

1996 • 770 citations

The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model.

1995 • 768 citations

B Cells Turn Off Virgin But Not Memory T Cells

1992 • 578 citations

A NEW ANALYSIS OF ALLOGENEIC INTERACTIONS

1975 • 551 citations

Establishment of Stable, Cell-Mediated Immunity that Makes "Susceptible" Mice Resistant to Leishmania major

1992 • 503 citations

Role of T‐Cell Derived Cytokines in the Downregulation of Immune Responses in Parasitic and Retroviral Infection

1992 • 473 citations

Assessment of Cytokines by Immunofluorescence and the Paraformaldehyde‐Saponin Procedure

1991 • 465 citations

In vivo effector function of influenza virus-specific cytotoxic T lymphocyte clones is highly specific.

1984 • 439 citations

Helminth infection results in decreased virus-specific CD8+ cytotoxic T-cell and Th1 cytokine responses as well as delayed virus clearance.

1993 • 363 citations

Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus: clearance of virus in vivo

1984 • 296 citations

Derivation of a T cell line that is highly responsive to IL-4 and IL-2 (CT.4R) and of an IL-2 hyporesponsive mutant of that line (CT.4S).

1989 • 289 citations

The Relationship Between Humoral and Cell‐Mediated Immunity

1972 • 228 citations

Ontogeny of mouse lymphocyte function. II. Development of the ability to produce antibody is modulated by T lymphocytes.

1975 • 220 citations

A Spontaneous Lower Motor Neuron Disease Apparently Caused by Indigenous Type-C RNA Virus in Wild Mice2

1973 • 200 citations

Split Anergy in a CD8 ⁺ T Cell: Receptor-dependent Cytolysis in the Absence of Interleukin-2 Production

1991 • 199 citations

ENHANCED TYPE 2 AND DIMINISHED TYPE 1 CYTOKINES IN NEONATAL TOLERANCE

1995 • 148 citations

MATURATION OF THE HUMORAL IMMUNE RESPONSE IN MICE

1974 • 130 citations

Selective Activation of Th1‐ and Th2‐like Cells in vivo– Response to Human Collagen IV

1991 • 129 citations

Neonatal tolerance induction by class II alloantigens activates IL-4-secreting, tolerogen-responsive T cells.

1990 • 117 citations

In vivo effects of anti-IL-4 monoclonal antibody on neonatal induction of tolerance and on an associated autoimmune syndrome.

1990 • 93 citations

Post-thymic T lymphocyte maturation during ontogenesis.

1981 • 79 citations

During ontogeny, Ia-bearing accessory cells are found early in the thymus but late in the spleen.

1980 • 71 citations

Isolation of transplantable erythroleukemia cells from mice infected with helper-independent Friend murine leukemia virus

1981 • 64 citations

T-cell tolerance: exposure to virus in utero does not cause a permanent deletion of specific T cells.

1988 • 59 citations

Up-regulation of murine neonatal T helper cell responses by accessory cell factors.

1994 • 49 citations

Peripheral tolerance mechanisms prevent the development of autoreactive T cells in chimeras grafted with two minor incompatible thymuses

1989 • 44 citations

Ontogeny of cell-mediated immunity. I. Early development of alloantigen-specific cytotoxic T-cell precursors in postnatal mice.

1977 • 40 citations

Pathogenesis of paralysis and lymphoma associated with a wild mouse retrovirus infection

1981 • 39 citations

Role of immunity in age-related resistance to paralysis after murine leukemia virus infection

1984 • 32 citations

Prevention of rejection by treatment of the graft: an overview.

1986 • 20 citations

Virus-specific cytotoxic lymphocyte response in a neurotropic murine leukemia virus infection

1991 • 15 citations

Effects of viral specific cytotoxic lymphocytes on the expression of murine leukemia virus induced neurologic disease

1991 • 14 citations

Ultraviolet-Light-Inactivated Cas-Br-M Murine Leukemia Virus Induces a Protective CD8⁺Cytotoxic T Lymphocyte Response in Newborn Mice

1994 • 13 citations

LFN-γ Production in Response to Neuropathogenic Cas-Br-M Murine Leukemia Virus Infection

1993 • 8 citations

Immunogenic determinants of a neuropathogenic murine leukemia virus

1995 • 6 citations