Helminth infection results in decreased virus-specific CD8+ cytotoxic T-cell and Th1 cytokine responses as well as delayed virus clearance.

CD8 ⁺ Lymphocytes Can Control HIV Infection in Vitro by Suppressing Virus Replication

1986 • 1,010 citations

Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni.

1991 • 777 citations

Egg deposition is the major stimulus for the production of Th2 cytokines in murine schistosomiasis mansoni.

1991 • 542 citations

An immunodominant epitope of the human immunodeficiency virus envelope glycoprotein gp160 recognized by class I major histocompatibility complex molecule-restricted murine cytotoxic T lymphocytes.

1988 • 417 citations

Roles of alphabeta and gammadelta T Cell Subsets in Viral Immunity

1992 • 350 citations

Production of IL-10 by CD4+ T lymphocytes correlates with down-regulation of Th1 cytokine synthesis in helminth infection.

1991 • 312 citations

Derivation of a T cell line that is highly responsive to IL-4 and IL-2 (CT.4R) and of an IL-2 hyporesponsive mutant of that line (CT.4S).

1989 • 289 citations

Regulation and biological function of helminth-induced cytokine responses

1991 • 260 citations

A cytotoxic T lymphocyte inhibits acquired immunodeficiency syndrome virus replication in peripheral blood lymphocytes.

1989 • 258 citations

Infection with Schistosoma mansoni alters Th1/Th2 cytokine responses to a non-parasite antigen.

1992 • 256 citations

Expression of the HTLV-III envelope gene by a recombinant vaccinia virus

1986 • 240 citations

Biological and immunological properties of human immunodeficiency virus type 1 envelope glycoprotein: analysis of proteins with truncations and deletions expressed by recombinant vaccinia viruses

1991 • 231 citations

Elevation of total serum IgE in rats following helminth parasite infection

1974 • 174 citations

Cytolytic T Lymphocytes

1983 • 119 citations

The antiviral activity of immune CD8+ T cells is dependent on interferon-gamma.

1991 • 98 citations

Broad recognition of cytotoxic T cell epitopes from the HIV-1 envelope protein with multiple class I histocompatibility molecules.

1992 • 97 citations

Functions of Purified L3T4⁺ and Lyt‐2⁺ Cells in vitro and in vivo

1986 • 92 citations

A sensitive immunochemical assay for biologically active MuIFN-γ

1987 • 79 citations

HIV epidemiology: past, present, and future

1991 • 59 citations

The relationship between uncomplicated schistosomiasis and hepatitis B infection

1989 • 47 citations

Chronic hepatitis B in patients with schistosomiasis mansoni.

1983 • 36 citations

Reexamination of the efficacy of vaccination against mousepox.

1985 • 26 citations

Lack of association between schistosomiasis and hepatitis B virus infection in Gezira-Managil area, Sudan

1991 • 26 citations

Risk of Hepatitis B Infection among Egyptians Infected with Schistosoma mansoni

1986 • 19 citations

Mouse hepatitis virus (MHV3) infection in chronic murine schistosomiasis mansoni.

1969 • 15 citations