Split Anergy in a CD8 ⁺ T Cell: Receptor-dependent Cytolysis in the Absence of Interleukin-2 Production

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

A Cell Culture Model for T Lymphocyte Clonal Anergy

1990 • 1,894 citations

Identification of a monoclonal antibody specific for a murine T3 polypeptide.

1987 • 1,644 citations

Clonal Expansion Versus Functional Clonal Inactivation: A Costimulatory Signalling Pathway Determines the Outcome of T Cell Antigen Receptor Occupancy

1989 • 1,512 citations

Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo.

1987 • 1,166 citations

Contingent Genetic Regulatory Events in T Lymphocyte Activation

1989 • 1,108 citations

Antigen recognition by H-2-restricted T cells. I. Cell-free antigen processing.

1983 • 701 citations

The Role of the T3/Antigen Receptor Complex in T-Cell Activation

1986 • 627 citations

The Role of the T Cell Receptor in Positive and Negative Selection of Developing T Cells

1990 • 589 citations

Stimulation of normal inducer T cell clones with antigen presented by purified Ia molecules in planar lipid membranes: specific induction of a long-lived state of proliferative nonresponsiveness.

1987 • 391 citations

Monoclonal cytolytic T-cell lines.

1979 • 364 citations

A Nondeletional Mechanism of Thymic Self Tolerance

1989 • 322 citations

Molecular events in the induction of a nonresponsive state in interleukin 2-producing helper T-lymphocyte clones.

1987 • 310 citations

Allogeneic non-T spleen cells restore the responsiveness of normal T cell clones stimulated with antigen and chemically modified antigen-presenting cells.

1988 • 260 citations

T Cell Activation Induces Rapid Tyrosine Phosphorylation of a Limited Number of Cellular Substrates

1989 • 258 citations

Cell growth cycle block of T cell hybridomas upon activation with antigen.

1987 • 235 citations

T-cell Clonal Anergy

1989 • 163 citations

Clonal deletion and clonal anergy in the thymus induced by cellular elements with different radiation sensitivities.

1990 • 146 citations

Antigen-driven helper cell-independent cloned cytolytic T lymphocytes

1981 • 128 citations

Characterization of two distinct primary T cell populations that secrete interleukin 2 upon recognition of class I or class II major histocompatibility antigens.

1986 • 90 citations

Tolerance induction of allo-class I H-2 antigen-reactive Lyt-2+ helper T cells and prolonged survival of the corresponding class I H-2-disparate skin graft.

1989 • 59 citations

Evidence for involvement of dual-function T cells in rejection of MHC class I disparate skin grafts. Assessment of MHC class I alloantigens as in vivo helper determinants.

1988 • 47 citations

Induction of IL 2 responsiveness in a murine IL 3-dependent cell line.

1985 • 44 citations

Distinct proliferative T cell clonotypes are generated in response to a murine retrovirus-induced syngeneic T cell leukemia: viral gp70 antigen-specific MT4+ clones and Lyt-2+ cytolytic clones which recognize a tumor-specific cell surface antigen.

1985 • 44 citations

Autonomously proliferating K/D‐restricted cytolytic T cell clones

1983 • 44 citations

Helper cell-independent cytolytic T lymphocytes specific for a minor histocompatibility antigen.

1983 • 40 citations

Consequences of self-presentation of peptide antigen by cytolytic T lymphocytes.

1989 • 21 citations