Gene Array and Protein Expression Profiles Suggest Post-transcriptional Regulation during CD8+ T Cell Differentiation

Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation

2000 • 4,853 citations

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

2001 • 2,746 citations

14-3-3 Proteins: Structure, Function, and Regulation

2000 • 1,552 citations

INDUCTION OF TH1 AND TH2 CD4⁺T CELL RESPONSES:The Alternative Approaches

1997 • 1,464 citations

The Duration of Antigenic Stimulation Determines the Fate of Naive and Effector T Cells

1998 • 890 citations

Differential Requirements for Survival and Proliferation of CD8 Naïve or Memory T Cells

1997 • 875 citations

Helper T Cell Differentiation Is Controlled by the Cell Cycle

1998 • 862 citations

Modulation of Chromatin Structure Regulates Cytokine Gene Expression during T Cell Differentiation

1998 • 697 citations

T Cell Receptor Signaling Precedes Immunological Synapse Formation

2002 • 695 citations

Signaling and Transcription in T Helper Development

2000 • 635 citations

Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice

1988 • 505 citations

Reactive Oxygen Species Regulate Activation-Induced T Cell Apoptosis

1999 • 485 citations

Reduced MAP Kinase Phosphatase-1 Degradation After p42/p44 ^MAPK -Dependent Phosphorylation

1999 • 414 citations

The molecular basis of T helper 1 and T helper 2 cell differentiation

2000 • 400 citations

RGS2/G0S8 is a selective inhibitor of Gqα function

1997 • 342 citations

BTG1, a member of a new family of antiproliferative genes.

1992 • 298 citations

TRANSCRIPTIONAL REGULATION OF T LYMPHOCYTE DEVELOPMENT AND FUNCTION

1999 • 293 citations

Glucose is essential for proliferation and the glycolytic enzyme induction that provokes a transition to glycolytic energy production.

1994 • 293 citations

Regulation of T cell activation, anxiety, and male aggression by RGS2

2000 • 278 citations

Tob is a negative regulator of activation that is expressed in anergic and quiescent T cells

2001 • 270 citations

In search of a function for the TIS21/PC3/BTG1/TOB family

2001 • 246 citations

Activation changes the spectrum but not the diversity of genes expressed by T cells

1999 • 227 citations

Increased TCR avidity after T cell activation: a mechanism for sensing low-density antigen.

2001 • 219 citations

How self-tolerance and the immunosuppressive drug FK506 prevent B-cell mitogenesis

2000 • 212 citations

The gene PC3^TIS21/BTG2, prototype member of the PC3/BTG/TOB family: Regulator in control of cell growth, differentiation, and DNA repair?

2001 • 207 citations

The role of the Crabtree effect and an endogenous fuel in the energy metabolism of resting and proliferating thymocytes

1993 • 206 citations

Glutamine and glucose metabolism during thymocyte proliferation. Pathways of glutamine and glutamate metabolism

1985 • 188 citations

B‐lymphocyte quiescence, tolerance and activation as viewed by global gene expression profiling on microarrays

2000 • 186 citations

B7-1 Engagement of Cytotoxic T Lymphocyte Antigen 4 Inhibits T Cell Activation in the Absence of CD28

1998 • 179 citations

Isolation of a gene encoding a putative leucine zipper structure that is induced by transforming growth factor beta 1 and other growth factors.

1992 • 151 citations

Gene Expression in Antigen-Specific CD8+ T Cells During Viral Infection

2001 • 130 citations

KIR expression on self-reactive CD8+ T cells is controlled by T-cell receptor engagement

2000 • 129 citations

A Human Gene Encoding a Putative Basic Helix–Loop–Helix Phosphoprotein Whose mRNA Increases Rapidly in Cycloheximide-Treated Blood Mononuclear Cells

1994 • 118 citations

Transforming Growth Factor-β-stimulated Clone-22 Is a Member of a Family of Leucine Zipper Proteins That Can Homo- and Heterodimerize and Has Transcriptional Repressor Activity

1999 • 110 citations

Regulation of T cell lymphokine production by killer cell inhibitory receptor recognition of self HLA class I alleles.

1996 • 109 citations

Catalytic activation of mitogen-activated protein (MAP) kinase phosphatase-1 by binding to p38 MAP kinase: critical role of the p38 C-terminal domain in its negative regulation

2000 • 108 citations

Substrate Recognition Domains within Extracellular Signal-regulated Kinase Mediate Binding and Catalytic Activation of Mitogen-activated Protein Kinase Phosphatase-3

2000 • 96 citations

Regulation of c-Jun NH2-terminal Kinase ( Jnk) Gene Expression during T Cell Activation

2000 • 93 citations

B7.1 Is a Quantitatively Stronger Costimulus Than B7.2 in the Activation of Naive CD8+ TCR-Transgenic T Cells

1998 • 77 citations

Down-regulation of TSC-22 (transforming growth factor beta-stimulated clone 22) markedly enhances the growth of a human salivary gland cancer cell line in vitro and in vivo.

1998 • 73 citations

Comparison of mRNA Expression of Two Regulators of G-Protein Signaling,RGS1/BL34/1R20andRGS2/G0S8, in Cultured Human Blood Mononuclear Cells

1997 • 67 citations

Mechanism of apoptotic cell death of human gastric carcinoma cells mediated by transforming growth factor β

1997 • 61 citations

T–cell proliferationin vivoand the role of cytokines

2000 • 61 citations

14-3-3 proteins and growth control

2000 • 60 citations

Differences Between Responses of Naive and Activated T Cells to Anergy Induction

1998 • 56 citations

Absence of CTLA-4 Lowers the Activation Threshold of Primed CD8+ TCR-Transgenic T Cells: Lack of Correlation with Src Homology Domain 2-Containing Protein Tyrosine Phosphatase

2001 • 47 citations

Over-Expression of TSC-22 (TGF-β Stimulated Clone-22) Markedly Enhances 5-Fluorouracil-Induced Apoptosis in a Human Salivary Gland Cancer Cell Line

2000 • 39 citations

Increased formation of reactive oxygen species due to glucose depletion in primary cultures of rat thymocytes inhibits proliferation

2000 • 29 citations

The role of co-stimulation in regulation of chemokine receptor expression and HIV-1 infection in primary T lymphocytes

1998 • 21 citations

Requirements for activation of CD8+Murine T cells

1994 • 11 citations