Alz-50 immunohistochemistry in the normal sheep striatum: a light and electron microscope study

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

THE HEAT-SHOCK RESPONSE

1986 • 4,580 citations

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1991 • 4,533 citations

The molecular pathology of Alzheimer's disease

1991 • 2,603 citations

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

1989 • 2,308 citations

Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures.

1991 • 2,173 citations

Neurotrophic and Neurotoxic Effects of Amyloid β Protein: Reversal by Tachykinin Neuropeptides

1990 • 1,975 citations

Neuronal NADPH diaphorase is a nitric oxide synthase.

1991 • 1,917 citations

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

1992 • 1,602 citations

Early-onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene

1991 • 1,191 citations

Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin

1977 • 878 citations

Selective Sparing of a Class of Striatal Neurons in Huntington's Disease

1985 • 767 citations

DEFECTIVE BRAIN MICROTUBULE ASSEMBLY IN ALZHEIMER'S DISEASE

1986 • 704 citations

Demonstration of a unique population of neurons with NADPH-diaphorase histochemistry

1983 • 687 citations

A Neuronal Antigen in the Brains of Alzheimer Patients

1986 • 577 citations

Cellular and biochemical events in mammalian cells during and after recovery from physiological stress.

1986 • 513 citations

Hydrofluoric acid-treated tau PHF proteins display the same biochemical properties as normal tau.

1992 • 509 citations

Chronic quinolinic acid lesions in rats closely resemble Huntington's disease

1991 • 497 citations

Conservation of Brain Amyloid Proteins in Aged Mammals and Humans with Alzheimer's Disease

1987 • 472 citations

Localization of 70-kDa stress protein induction in gerbil brain after ischemia

1988 • 465 citations

Amyloid β-protein deposition in tissues other than brain in Alzheimer's disease

1989 • 433 citations

Monoclonal antibodies directed against the calcium binding protein parvalbumin

1988 • 427 citations

Parvalbumin-immunoreactive neurons in the rat neostriatum: a light and electron microscopic study

1990 • 408 citations

Phosphorylation determines two distinct species of tau in the central nervous system

1987 • 405 citations

A Golgi study of neuronal types in the neostriatum of monkeys

1976 • 355 citations

Expression of multiple tau isoforms and microtubule bundle formation in fibroblasts transfected with a single tau cDNA.

1989 • 354 citations

Immunochemical analysis of the turnover of ubiquitin-protein conjugates in intact cells. Relationship to the breakdown of abnormal proteins.

1982 • 293 citations

Non-NMDA receptor-mediated neurotoxicity in cortical culture

1990 • 291 citations

Organization of microtubules in dendrites and axons is determined by a short hydrophobic zipper in microtubule-associated proteins MAP2 and tau

1989 • 281 citations

Synthesis of a Stress Protein Following Transient Ischemia in the Gerbil

1985 • 270 citations

Striatal neurons containing both somatostatin‐ and avian pancreatic polypeptide (APP)‐like immunoreactivities and NADPH‐diaphorase activity: A light and electron microscopic study

1983 • 267 citations

Characterization and purification of the small 28,000-dalton mammalian heat shock protein.

1987 • 263 citations

Localization of Alzheimer βA4 amyloid precursor protein at central and peripheral synaptic sites

1991 • 259 citations

Cortical somatostatin, neuropeptide Y, and NADPH diaphorase neurons: Normal anatomy and alterations in alzheimer's disease

1988 • 219 citations

The purification of tau protein and the occurrence of two phosphorylation states of tau in brain.

1984 • 189 citations

Alz‐50 Antibody recognizes alzheimer‐related neuronal changes

1988 • 177 citations

Abnormal phosphorylation of tau precedes ubiquitination in neurofibrillary pathology of Alzheimer disease

1991 • 177 citations

Alzheimer‐related neuronal protein A68: Specificity and distribution

1987 • 176 citations

Study of the rat neostriatum using a combined Golgi-electron microscope technique and serial sections

1980 • 174 citations

Ubiquitin immunoreactive structures in normal human brains. Distribution and developmental aspects.

1990 • 170 citations

A Golgi study of the human neostriatum: Neurons and afferent fibers

1985 • 161 citations

Neuropeptide Y, somatostatin, and reduced nicotinamide adenine dinucleotide phosphate diaphorase in the human striatum: A combined immunocytochemical and enzyme histochemical study

1987 • 159 citations

Immunocytochemical localization of the precursor protein for β-amyloid in the rat central nervous system

1988 • 153 citations

Fine structural studies on a type of somatostatin‐immurioreactive neuron and its synaptic connections in the rat neostriatum: A correlated light and electron microscopic study

1983 • 150 citations

Neuropeptide Y-immunoreactive neurons in the striatum of cat and monkey: Morphological characteristics, intrinsic organization and co-localization with somatostatin

1986 • 143 citations

Ultrastructural correlates of functional relationships between nigral dopaminergic or cortical afferent fibers and neuropeptide Y-containing neurons in the rat striatum

1989 • 132 citations

Alzheimer disease proteins (A68) share epitopes with tau but show distinct biochemical properties

1990 • 115 citations

Morphological taxonomy of the neurons of the primate striatum

1991 • 111 citations

A simple ordering of neocortical areas established by the compartmental organization of their striatal projections.

1990 • 111 citations

Alz 50, a monoclonal antibody to Alzheimer's disease antigen, cross-reacts with tau proteins from bovine and normal human brain.

1988 • 107 citations

Neuronal types in the striatum of man

1982 • 103 citations

A new enzyme marker for striatal compartmentalization: NADPH diaphorase activity in the caudate nucleus and putamen of the cat

1986 • 96 citations

Alz-50 recognizes a phosphorylated epitope of tau protein

1990 • 93 citations

Tau in situ hybridization in normal and alzheimer brain: Localization in the somatodendritic compartment

1989 • 88 citations

Localization of the Alz-50 epitope in recombinant human microtubule-associated protein tau

1991 • 86 citations

Somatostatin- and Neuropeptide Y-immunoreactive neurons in the neocortex in senile dementia of alzheimer's type

1986 • 78 citations

Widespread expression of amyloid beta-protein precursor gene in rat brain.

1989 • 78 citations

Tau protein and Alzheimer's disease

1990 • 78 citations

Alz 50 recognizes abnormal filaments in Alzheimer's disease and progressive supranuclear palsy

1988 • 74 citations

Aspiny neurons and their local axons in the neostriatum of the rat: a correlated light and electron microscopic study of Golgi-impregnated material

1984 • 70 citations

Tau protein immunoreactivity in dementia of the Alzheimer type: II. Electron microscopy and pathogenetic implications. Effects of fixation on the morphology of the Alzheimer's abnormal filaments.

1989 • 65 citations

Neuropeptide Y-immunoreactive neurons receive synaptic inputs from dopaminergic axon terminals in the rat neostriatum

1988 • 64 citations

Mapping of the Alz 50 epitope in microtubule‐associated proteins tau

1990 • 60 citations

The amygdala in Alzheimer's disease: Neuropathology and Alz 50 Immunoreactivity

1991 • 54 citations

Immunohistochemical evidence for a possible somatostatin-containing amygdalostriatal pathway in normal and Alzheimer's disease brain

1988 • 48 citations

Alz‐50 immunoreactive neuropil differentiates hippocampal complex subfields in Alzheimer's disease

1991 • 40 citations

Phosphorylation characteristics of the A68 protein in Alzheimer's disease

1990 • 36 citations

Alz‐50 immunoreactivity in the hypothalamus of the normal and Alzheimer human and the rat

1991 • 32 citations

The distribution of Alz-50 immunoreactivity in the normal human brain

1993 • 32 citations

Spectrum of amyloid β-protein immunoreactivity in hereditary Alzheimer disease with a guanine to thymine missence change at position 1924 of the APP gene

1992 • 24 citations

ATP-induced loss of Alz-50 immunoreactivity with the A68 proteins from Alzheimer brain is mediated by ubiquitin.

1990 • 18 citations

Further observations on the spiny neurons and synaptic endings in the striatum of the monkey (Saimiri sciureus).

1971 • 16 citations

N-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induces cytoskeletal alterations on ‘Swiss 3T3’ mouse fibroblasts

1991 • 14 citations

High frequency of ciliated neuropeptide Y-immunoreactive neurons in rat striatum

1992 • 9 citations