Influence of the Redox State of Pyridine Nucleotides on Mitochondrial Sulfhydryl Groups and Permeability Transition

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Tissue sulfhydryl groups

1959 • 25,130 citations

DETERMINATION OF SERUM PROTEINS BY MEANS OF THE BIURET REACTION

1949 • 16,078 citations

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues

1969 • 6,007 citations

[70] Determination of glutathione and glutathione disulfide in biological samples

1985 • 2,678 citations

The mitochondrial permeability transition

1995 • 2,412 citations

Mechanisms by which mitochondria transport calcium

1990 • 1,630 citations

Inhibition by cyclosporin A of a Ca2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress.

1988 • 846 citations

The Ca2+-induced membrane transition in mitochondria

1979 • 826 citations

The Ca2+-induced membrane transition in mitochondria

1979 • 751 citations

Water Uptake and Extrusion by Mitochondria in Relation to Oxidative Phosphorylation

1962 • 550 citations

The enzymic hydrolysis of adenosine triphosphate by liver mitochondria. 1. Activities at different pH values

1957 • 548 citations

The voltage sensor of the mitochondrial permeability transition pore is tuned by the oxidation-reduction state of vicinal thiols. Increase of the gating potential by oxidants and its reversal by reducing agents

1994 • 527 citations

Modulation of the Mitochondrial Permeability Transition Pore by Pyridine Nucleotides and Dithiol Oxidation at Two Separate Sites

1996 • 522 citations

The permeability transition pore as a mitochondrial calcium release channel: A critical appraisal

1996 • 466 citations

Regulation of Ca ²⁺ release from mitochondria by the oxidation-reduction state of pyridine nucleotides

1978 • 364 citations

Functions of Glutathione in Liver and Kidney

1978 • 352 citations

Physiological roles of nicotinamide nucleotide transhydrogenase

1988 • 348 citations

Permeabilization of the inner mitochondrial membrane by Ca2+ ions is stimulated by t-butyl hydroperoxide and mediated by reactive oxygen species generated by mitochondria

1995 • 248 citations

The inner mitochondrial membrane contains ion‐conducting channels similar to those found in bacteria

1989 • 224 citations

Hydroperoxides can modulate the redox state of pyridine nucleotides and the calcium balance in rat liver mitochondria

1979 • 205 citations

Membrane protein thiol cross-linking associated with the permeabilization of the inner mitochondrial membrane by Ca2+ plus prooxidants.

1990 • 198 citations

Ca(2+)-induced mitochondrial membrane permeabilization: role of coenzyme Q redox state

1995 • 187 citations

Effects of phospholipase A2 inhibitors on ruthenium red-induced Ca2+ release from mitochondria.

1985 • 160 citations

BIOCHEMICAL STRUCTURE OF MITOCHONDRIA

1955 • 159 citations

Allosteric inhibition of the Ca2+-activated hydrophilic channel of the mitochondrial inner membrane by nucleotides

1980 • 157 citations

The Effect of Thiols and Disulfides on Water Uptake and Extrusion by Rat Liver Mitochondria

1962 • 155 citations

The Participation of Reactive Oxygen Species and Protein Thiols in the Mechanism of Mitochondrial Inner Membrane Permeabilization by Calcium plus Prooxidants

1993 • 139 citations

Calcium and pyridine nucleotide interaction in mitochondrial membranes

1972 • 128 citations

Stimulation of mitochondrial calcium ion efflux by thiol-specific reagents and by thyroxine. The relationship to adenosine diphosphate retention and to mitochondrial permeability

1979 • 96 citations

The control of Ca2+ release from heart mitochondria.

1981 • 95 citations

Changes in Sulfhydryl Groups of Rat Liver Mitochondria During Swelling and Contraction

1964 • 87 citations

Tert-butyl hydroperoxide-induced radical production in rat liver mitochondria

1992 • 81 citations

The stability of oxidative and phosphorylative systems in mitochondria under anaerobic conditions

1956 • 76 citations

Relationships between the NAD(P) redox state, fatty acid oxidation, and inner membrane permeability in rat liver mitochondria

1989 • 65 citations

Mitochondrial lipid peroxidation by cumene hydroperoxide and its prevention by succinate

1982 • 64 citations

Mechanism of depletion of mitochondrial pyridine nucleotides

1960 • 52 citations

Inhibition of Rat Liver Mitochondrial Permeability Transition by Respiratory Substrates

1995 • 40 citations

Relation between the Activities Reducing Disulfides and the Protection against Membrane Permeability Transition in Rat Liver Mitochondria

1996 • 34 citations

Mitochondria: DNA proteins and disease

1995 • 32 citations

Mitochondria: DNA proteins and disease

1994 • 29 citations

Comparison of cumene hydroperoxide- and NADPH/Fe3+/ADP-induced lipid peroxidation in heart and liver submitochondrial particles

1984 • 29 citations

Calcium-ion transport by intact Ehrlich ascites-tumour cells. Role of respiratory substrates, Pi and temperature

1978 • 22 citations

The coupling of metabolic to secretory events in pancreatic islets. Glucose-induced changes in mitochondrial redox state

1996 • 18 citations

Interrelation between mitochondrial respiration, substrate supply and redox ratio in perifused permeabilized rat hepatocytes

1996 • 8 citations

Inhibition of the pyridine nucleotide-linked mitochondrial Ca²⁺release by 4-hydroxynonenal: the role of thiolate-disulfide conversion

1996 • 8 citations

Regulation of lipid peroxidation by ATP synthetase substrates in rat liver mitochondria

1986 • 6 citations