Permeabilization of the inner mitochondrial membrane by Ca2+ ions is stimulated by t-butyl hydroperoxide and mediated by reactive oxygen species generated by mitochondria

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Mechanisms by which mitochondria transport calcium

1990 • 1,630 citations

OXIDATION OF FREE AMINO ACIDS AND AMINO ACID RESIDUES IN PROTEINS BY RADIOLYSIS AND BY METAL-CATALYZED REACTIONS

1993 • 1,377 citations

Role of Ca2+ in toxic cell killing

1989 • 856 citations

The anion transport system of the red blood cell The role of membrane protein evaluated by the use of ‘probes’

1978 • 722 citations

Considerations in the spin trapping of superoxide and hydroxyl radical in aqueous systems using 5,5-dimethyl-1-pyrroline-1-oxide

1978 • 569 citations

Blebbing, free Ca2+ and mitochondrial membrane potential preceding cell death in hepatocytes

1987 • 533 citations

Modulation of the mitochondrial permeability transition pore. Effect of protons and divalent cations.

1992 • 449 citations

Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by the proton electrochemical gradient. Evidence that the pore can be opened by membrane depolarization.

1992 • 443 citations

Method of determining oxygen concentrations in biological media, suitable for calibration of the oxygen electrode

1970 • 382 citations

The giant channel of the inner mitochondrial membrane is inhibited by cyclosporin A

1991 • 368 citations

Regulation of Ca ²⁺ release from mitochondria by the oxidation-reduction state of pyridine nucleotides

1978 • 364 citations

Enhancement of hydrogen peroxide formation by protophores and ionophores in antimycin-supplemented mitochondria

1980 • 273 citations

The mitochondrial megachannel is the permeability transition pore

1992 • 262 citations

Mechanism of calcium potentiation of oxygen free radical injury to renal mitochondria. A model for post-ischemic and toxic mitochondrial damage.

1986 • 258 citations

Modulation of the mitochondrial megachannel by divalent cations and protons.

1992 • 232 citations

Stoichiometry of H+ ejection and Ca2+ uptake coupled to electron transport in rat heart mitochondria.

1978 • 228 citations

The role of glutathione in the retention of Ca2+ by liver mitochondria.

1984 • 223 citations

Methods in toxicology

1970 • 210 citations

Membrane protein thiol cross-linking associated with the permeabilization of the inner mitochondrial membrane by Ca2+ plus prooxidants.

1990 • 198 citations

Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by matrix pH. Evidence that the pore open-closed probability is regulated by reversible histidine protonation

1993 • 181 citations

Mitochondrial Generation of Oxygen Radicals During Reoxygenation of Ischemic Tissues

1991 • 174 citations

The Participation of Reactive Oxygen Species and Protein Thiols in the Mechanism of Mitochondrial Inner Membrane Permeabilization by Calcium plus Prooxidants

1993 • 139 citations

Subcellular characteristics of phospholipase A2 activity in the rat kidney. Enhanced cytosolic, mitochondrial, and microsomal phospholipase A2 enzymatic activity after renal ischemia and reperfusion.

1991 • 115 citations

Review of the current status of calcium and thiols in cellular injury

1990 • 98 citations

Tert-butyl hydroperoxide-induced radical production in rat liver mitochondria

1992 • 81 citations

Ca2+-mediated activation of phosphoenolpyruvate carboxykinase occurs via release of Fe2+ from rat liver mitochondria.

1982 • 40 citations

The Catalase Requirement in the Reversal of Mitochondrial Swelling Caused by Reduced Glutathione and by Trace Metals

1967 • 11 citations

Generation of Reactive Oxygen Metabolites and Oxidative Damage in Mitochondria: Role of Calcium

1993 • 11 citations