Obesity-Induced Lymphocyte Hyperresponsiveness to Chemokines: A New Mechanism of Fatty Liver Inflammation in Obese Mice

Design and validation of a histological scoring system for nonalcoholic fatty liver disease

2005 • 9,483 citations

Nonalcoholic Fatty Liver Disease

2002 • 5,091 citations

Leptin regulates proinflammatory immune responses

1998 • 1,161 citations

Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections

2005 • 1,111 citations

The Chemokine SDF-1/CXCL12 Binds to and Signals through the Orphan Receptor RDC1 in T Lymphocytes

2005 • 1,023 citations

Cytokines in Alcoholic and Nonalcoholic Steatohepatitis

2000 • 936 citations

Nonalcoholic Steatohepatitis: Definition and Pathology

2001 • 919 citations

The weight of leptin in immunity

2004 • 876 citations

The role of small intestinal bacterial overgrowth, intestinal permeability, endotoxaemia, and tumour necrosis factor alpha in the pathogenesis of non-alcoholic steatohepatitis

2001 • 820 citations

Obesity increases sensitivity to endotoxin liver injury: Implications for the pathogenesis of steatohepatitis

1997 • 815 citations

B Cell–attracting Chemokine 1, a Human CXC Chemokine Expressed in Lymphoid Tissues, Selectively Attracts B Lymphocytes via BLR1/CXCR5

1998 • 807 citations

Increased intestinal permeability in obese mice: new evidence in the pathogenesis of nonalcoholic steatohepatitis

2006 • 800 citations

A Key Role of Leptin in the Control of Regulatory T Cell Proliferation

2007 • 609 citations

Leptin regulates proinflammatory immune responses

1998 • 487 citations

Chemokines: signal lamps for trafficking of T and B cells for development and effector function

1999 • 348 citations

Leptin deficiency enhances sensitivity to endotoxin-induced lethality

1999 • 287 citations

Chemokine-mediated control of T cell traffic in lymphoid and peripheral tissues

2004 • 287 citations

Dietary factors alter hepatic innate immune system in mice with nonalcoholic fatty liver disease

2005 • 284 citations

Attenuated liver fibrosis in the absence of B cells

2005 • 251 citations

Cellular and molecular mechanisms of liver tolerance

2006 • 227 citations

Hepatic inflammation in rats with experimental small intestinal bacterial overgrowth

1990 • 211 citations

Hepatic microvascular dysfunction during evolution of dietary steatohepatitis in mice

2004 • 199 citations

Altered hepatic lymphocyte subpopulations in obesity-related murine fatty livers: Potential mechanism for sensitization to liver damage

2000 • 191 citations

Animal models of steatohepatitis

2002 • 173 citations

Adoptive transfer of regulatory NKT lymphocytes ameliorates non-alcoholic steatohepatitis and glucose intolerance in ob/ob mice and is associated with intrahepatic CD8 trapping

2006 • 112 citations

Stromal cell-derived factor 1 (SDF-1) and antenatal human B cell lymphopoiesis: Expression of SDF-1 by mesothelial cells and biliary ductal plate epithelial cells

1999 • 109 citations

Innate immunity in the liver

2003 • 109 citations

Intrahepatic immunity: a tale of two sites?

2005 • 106 citations

Critical role of CXC chemokines in endotoxemic liver injury in mice

2003 • 104 citations

Norepinephrine regulates hepatic innate immune system in leptin-deficient mice with nonalcoholic steatohepatitis

2004 • 103 citations

Nonalcoholic fatty liver disease: from pathogenesis to patient care

2007 • 99 citations

The CXCR5 Chemokine Receptor Is Expressed by Carcinoma Cells and Promotes Growth of Colon Carcinoma in the Liver

2006 • 98 citations

Clinicopathological significance of oxidative cellular damage in non-alcoholic fatty liver diseases

2005 • 93 citations

Increased Lipopolysaccharide Sensitivity in Alcoholic Fatty Livers Is Independent of Leptin Deficiency and Toll-Like Receptor 4 (TLR4) or TLR2 mRNA Expression

2005 • 24 citations