Interaction of Zyxin, a Focal Adhesion Protein, with the E6 Protein from Human Papillomavirus Type 6 Results in Its Nuclear Translocation

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

1990 • 3,896 citations

Cell Adhesion: The Molecular Basis of Tissue Architecture and Morphogenesis

1996 • 3,454 citations

Integrins and Signal Transduction Pathways: the Road Taken

1995 • 3,002 citations

Association of Human Papillomavirus Types 16 and 18 E6 Proteins with p53

1990 • 2,587 citations

FOCAL ADHESIONS, CONTRACTILITY, AND SIGNALING

1996 • 1,900 citations

The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes

1989 • 1,345 citations

DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.

1979 • 1,339 citations

Identification of a Ten-Amino Acid Proline-Rich SH3 Binding Site

1993 • 1,205 citations

Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product.

1989 • 1,186 citations

HPV16 E6 and E7 proteins cooperate to immortalize human foreskin keratinocytes.

1989 • 913 citations

Human papillomavirus types 6 and 11 DNA sequences in genital and laryngeal papillomas and in some cervical cancers.

1983 • 893 citations

Human papillomaviruses in the pathogenesis of anogenital cancer

1991 • 855 citations

MLP-Deficient Mice Exhibit a Disruption of Cardiac Cytoarchitectural Organization, Dilated Cardiomyopathy, and Heart Failure

1997 • 831 citations

Requirement for LIml in head-organizer function

1995 • 801 citations

The Oncogenic Cysteine-rich LIM domain protein Rbtn2 is essential for erythroid development

1994 • 616 citations

Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity

1998 • 602 citations

Recurrent rearrangements in the high mobility group protein gene, HMGI-C, in benign mesenchymal tumours

1995 • 575 citations

A vector for expressing GAL4(1–147) fusions tn mammalian cells

1989 • 558 citations

Novel cysteine-rich motif and homeodomain in the product of the Caenorhabditis elegans cell lineage gene lin-II

1990 • 550 citations

The LIM domain: regulation by association

2000 • 547 citations

Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.

1993 • 537 citations

Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein

1997 • 462 citations

The LIM domain is a modular protein-binding interface

1994 • 450 citations

The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300

1999 • 417 citations

Cell to substratum contacts of chick fibroblasts and their relation to the microfilament system. a correlated interference-reflexion and high-voltage electron-microscope study

1978 • 409 citations

Analysis of human genital warts (condylomata acuminata) and other genital tumors for human papillomavirus type 6 DNA

1982 • 353 citations

Identification of LIM3 as the principal determinant of paxillin focal adhesion localization and characterization of a novel motif on paxillin directing vinculin and focal adhesion kinase binding.

1996 • 347 citations

Zyxin and cCRP: two interactive LIM domain proteins associated with the cytoskeleton.

1992 • 344 citations

Transcriptional Repression by Blimp-1 (PRDI-BF1) Involves Recruitment of Histone Deacetylase

2000 • 328 citations

The LIM domain: a new structural motif found in zinc-finger-like proteins

1994 • 327 citations

Immortalization and altered differentiation of human keratinocytes in vitro by the E6 and E7 open reading frames of human papillomavirus type 18

1990 • 319 citations

Oncogenic human papillomavirus E6 proteins target the discs large tumour suppressor for proteasome-mediated degradation

1999 • 295 citations

Interaction of Papillomavirus E6 Oncoproteins with a Putative Calcium-Binding Protein

1995 • 272 citations

The bovine papillomavirus E6 oncoprotein interacts with paxillin and disrupts the actin cytoskeleton

1997 • 258 citations

The human papilloma virus (HPV)-18 E6 oncoprotein physically associates with Tyk2 and impairs Jak-STAT activation by interferon-α

1999 • 258 citations

An interaction between zyxin and alpha-actinin.

1992 • 251 citations

Nuclear–Cytoplasmic Shuttling of the Focal Contact Protein, Zyxin: A Potential Mechanism for Communication between Sites of Cell Adhesion and the Nucleus

1997 • 244 citations

Papillomavirus polypeptides E6 and E7 are zinc-binding proteins

1989 • 239 citations

Identification of the HPV-16 E6 protein from transformed mouse cells and human cervical carcinoma cell lines.

1987 • 230 citations

Zyxin: Zinc fingers at sites of cell adhesion

1997 • 213 citations

Human papillomavirus (HPV) E6 interactions with Bak are conserved amongst E6 proteins from high and low risk HPV types.

1999 • 209 citations

Cell-to-substratum contacts in living cells: A direct correlation between interference-reflexion and indirect-immunofluorescence microscopy using antibodies against actin and A-actinin

1979 • 196 citations

LPP,the Preferred Fusion Partner Gene ofHMGICin Lipomas, Is a Novel Member of the LIM Protein Gene Family

1996 • 196 citations

Zyxin, a Regulator of Actin Filament Assembly, Targets the Mitotic Apparatus by Interacting with H-Warts/Lats1 Tumor Suppressor

2000 • 193 citations

Cloning and Expression of the cDNA for E6-AP, a Protein that Mediates the Interaction of the Human Papillomavirus E6 Oncoprotein with p53

1993 • 190 citations

The E6 Oncoproteins of High-Risk Papillomaviruses Bind to a Novel Putative GAP Protein, E6TP1, and Target It for Degradation

1999 • 188 citations

LIM domain proteins.

1995 • 188 citations

The E6-E7 region of human papillomavirus type 18 is sufficient for transformation of NIH 3T3 and rat-1 cells

1987 • 180 citations

E3-Ubiquitin Ligase/E6-AP Links Multicopy Maintenance Protein 7 to the Ubiquitination Pathway by a Novel Motif, the L2G Box

1998 • 180 citations

Human papillomavirus type 16 transformation of primary human embryonic fibroblasts requires expression of open reading frames E6 and E7

1989 • 178 citations

Purification and characterization of zyxin, an 82,000-dalton component of adherens junctions.

1991 • 167 citations

Characterization of the Interaction between Zyxin and Members of the Ena/Vasodilator-stimulated Phosphoprotein Family of Proteins

2000 • 165 citations

LPP, an Actin Cytoskeleton Protein Related to Zyxin, Harbors a Nuclear Export Signal and Transcriptional Activation Capacity

2000 • 154 citations

Human papillomavirus infection and anal cancer

1989 • 153 citations

In vitro biological activities of the E6 and E7 genes vary among human papillomaviruses of different oncogenic potential

1991 • 150 citations

Peg3/Pw1 is an imprinted gene involved in the TNF-NFκB signal transduction pathway

1998 • 148 citations

Identification of a new protein localized at sites of cell-substrate adhesion.

1986 • 132 citations

Association of Bovine Papillomavirus Type 1 E6 oncoprotein with the focal adhesion protein paxillin through a conserved protein interaction motif

1998 • 132 citations

Biochemical and molecular characterization of the chicken cysteine-rich protein, a developmentally regulated LIM-domain protein that is associated with the actin cytoskeleton

1994 • 114 citations

Molecular Characterization of Human Zyxin

1996 • 112 citations

Molecular Dissection of Zyxin Function Reveals Its Involvement in Cell Motility

1999 • 110 citations

HPV E6 targeted degradation of the discs large protein: evidence for the involvement of a novel ubiquitin ligase

2000 • 104 citations

The Bovine Papillomavirus E6 Protein Binds to the LD Motif Repeats of Paxillin and Blocks Its Interaction with Vinculin and the Focal Adhesion Kinase

1997 • 91 citations

Structural and functional similarities between the human cytoskeletal protein zyxin and the ActA protein of Listeria monocytogenes

1997 • 84 citations

Human Papillomavirus Oncoprotein E6 Binds to the C-Terminal Region of Human Minichromosome Maintenance 7 Protein

1998 • 80 citations

SH3 domain-dependent interaction of the proto-oncogene product Vav with the focal contact protein zyxin.

1996 • 80 citations

The HumanTRIP6Gene Encodes a LIM Domain Protein and Maps to Chromosome 7q22, a Region Associated with Tumorigenesis

1998 • 80 citations

The enigma of LIM domains

1995 • 72 citations

Intracellular localization and DNA-binding properties of human papillomavirus type 18 E6 protein expressed with a baculovirus vector

1989 • 63 citations

PKN Binds and Phosphorylates Human Papillomavirus E6 Oncoprotein

2000 • 60 citations

Role of the Cytoskeletal Protein Paxillin in Oncogenesis

2000 • 60 citations

Suppression in transformed avian fibroblasts of a gene (crp) encoding a cysteine-rich protein containing LIM domains.

1993 • 58 citations

Gps2, a Protein Partner for Human Papillomavirus E6 Proteins

2001 • 56 citations

Genetic Analysis of a Potential Zinc-binding Domain of the Adenovirus E4 34k Protein

2000 • 40 citations

Multiple-alphabet amino acid sequence comparisons of the immunoglobulin kappa-chain constant domain.

1985 • 40 citations

pALEX, a dual-tag prokaryotic expression vector for the purification of full-length proteins

1995 • 37 citations

Binding of the Human Immunodeficiency Virus Type 1 Gag Protein to the Viral RNA Encapsidation Signal in the Yeast Three-Hybrid System

1998 • 33 citations

New HPV E6 binding proteins: dangerous liaisons?

1998 • 23 citations

Deleted Work

1955 • 0 citations