Enhancement of heat-induced heat shock protein (hsp)72 accumulation by doxorubicin (Dox) in vitro

Adriamycin

1974 • 1,051 citations

Intercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II.

1984 • 896 citations

Heat shock resistance conferred by expression of the human HSP27 gene in rodent cells.

1989 • 699 citations

A general mechanism for microsomal activation of quinone anticancer agents to free radicals.

1978 • 645 citations

Effect of local hyperthermia on blood flow and microenvironment: a review.

1984 • 610 citations

Heat‐shock proteins as molecular chaperones

1994 • 551 citations

Induced thermal resistance in HeLa cells

1975 • 494 citations

Thermochemotherapy: synergism between hyperthermia (42-43 degrees) and adriamycin (of bleomycin) in mammalian cell inactivation.

1975 • 489 citations

Thermal response of rat fibroblasts stably transfected with the human 70-kDa heat shock protein-encoding gene.

1991 • 365 citations

Heat fractionation and thermotolerance: a review.

1978 • 364 citations

Response of human breast cancer cells to heat shock and chemotherapeutic drugs.

1992 • 247 citations

The small heat shock protein hsp27 is correlated with growth and drug resistance in human breast cancer cell lines.

1993 • 242 citations

Hyperthermia and Drugs

1987 • 170 citations

Cytotoxic Effects of Hyperthermia and Adriamycin on Chinese Hamster Cells2

1976 • 163 citations

Erythrophagocytosis induces heat shock protein synthesis by human monocytes-macrophages.

1990 • 118 citations

Transient cold shock induces the heat shock response upon recovery at 37 degrees C in human cells.

1994 • 103 citations

Combined adriamycin and hyperthermia treatment of a murine mammary carcinoma in vivo.

1976 • 94 citations

Oxygen free radicals as inducers of heat shock protein synthesis in cultured human neuroblastoma cells: Relevance to neurodegenerative disease

1993 • 81 citations

Expression of human hsp70 in rat fibroblasts enhances cell survival and facilitates recovery from translational and transcriptional inhibition following heat shock.

1992 • 79 citations

Binding between wild-type p53 and hsp72 accumulated after UV and γ-ray irradiation

1995 • 65 citations

Gamma Irradiation Increases hsp-70 in Chinese Hamster Ovary Cells

1993 • 61 citations

Heat-shock protein induction in adriamycin and picornavirus-infected cardiocytes.

1992 • 53 citations

Possible Correlation between DNA Damage Induced by Hydrogen Peroxide and Translocation of Heat Shock 70 Protein into the Nucleus

1995 • 46 citations

Induction of thermotolerance and sensitization in CHO cells by combined hyperthermic treatments at 40 and 43°C

1980 • 41 citations

8‐METHOXYPSORALEN PLUS UVA INDUCES THE 72 kDa HEAT SHOCK PROTEIN IN ORGAN‐CULTURED NORMAL HUMAN SKIN

1993 • 38 citations

Nitric oxide is an initiator of intercellular signal transduction for stress response after hyperthermia in mutant p53 cells of human glioblastoma.

1999 • 35 citations

Hyperthermic potentiation of doxorubicin and 4′-epi-doxorubicin in a transplantable neurogenic rat tumor (BT4A) in BD IX rats

1983 • 30 citations

Effect of ATP on the Release of hsp 70 and hsp 40 from the Nucleus in Heat-Shocked HeLa Cells

1993 • 25 citations

The interaction of thermal tolerance with drug cytotoxicity in vitro

1979 • 23 citations

Induction of the 72-kD Heat Shock Protein in Xeroderma Pigmentosum Complementation Group A Fibroblasts

1992 • 22 citations

Suppression of heat-induced HSF activation by CDDP in human glioblastoma cells

1998 • 21 citations

Actinomycin D and Radiation Fractionation Studies in Asynchronous and Synchronized Chinese Hamster Cells

1970 • 20 citations

Inhibition of Nucleolar Function and Morphological Change by Adriamycin Associated with Heat Shock Protein 70 Accumulation

1996 • 16 citations

Sensitivities of bleomycin-resistant variant cells enhanced by 40°C hyperthermiain vitro

1988 • 15 citations

Synthesis of heat shock proteins following oxidative challenge: role of glutathione

1994 • 15 citations

Suppression of heat-induced hsp72 accumulation by cisplatin in human glioblastoma cells

1996 • 14 citations

Effect of heat-drug sequences on thermoenhancement and uptake of cis-DDP in human pharyngeal carcinoma.

1996 • 13 citations

In vitroeffects of hyperthermia combined with cisplatin or peplomycin on the human maxillary carcinoma cell line IMC-2

1997 • 10 citations

Optimal scheduling increases therapeutic gain of adriamycin combined with hyperthermia.

1993 • 10 citations

Current research in hyperthermia oncology

1988 • 8 citations

Hyperthermia and chemotherapy: When will they be used in the clinical treatment of cancer?

1983 • 8 citations

[Effects of anti-tumor drugs on thermosensitivity of thermotolerant cells and thermotolerance development].

1986 • 6 citations