Liver injury in the setting of steatosis: Crosstalk between adipokine and cytokine

Paradoxical Decrease of an Adipose-Specific Protein, Adiponectin, in Obesity

1999 • 4,825 citations

Hypoadiponectinemia in Obesity and Type 2 Diabetes: Close Association with Insulin Resistance and Hyperinsulinemia

2001 • 3,408 citations

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

2003 • 3,114 citations

The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

2001 • 2,534 citations

Oxidative Stress and Stress-Activated Signaling Pathways: A Unifying Hypothesis of Type 2 Diabetes

2002 • 2,164 citations

Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice

2001 • 1,903 citations

Adiponectin, an Adipocyte-Derived Plasma Protein, Inhibits Endothelial NF-κB Signaling Through a cAMP-Dependent Pathway

2000 • 1,711 citations

Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages

2000 • 1,438 citations

Tumor Necrosis Factor α: A Key Component of the Obesity-Diabetes Link

1994 • 1,302 citations

Minireview: The Adipocyte—At the Crossroads of Energy Homeostasis, Inflammation, and Atherosclerosis

2003 • 1,192 citations

The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice

2003 • 1,155 citations

Structure-Function Studies of the Adipocyte-secreted Hormone Acrp30/Adiponectin

2003 • 1,063 citations

The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice

2003 • 1,056 citations

Adiponectin Reduces Atherosclerosis in Apolipoprotein E-Deficient Mice

2002 • 1,028 citations

Beyond insulin resistance in NASH: TNF-? or adiponectin?

2004 • 934 citations

Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease

2003 • 893 citations

Obesity increases sensitivity to endotoxin liver injury: Implications for the pathogenesis of steatohepatitis

1997 • 815 citations

Regulation of Fasted Blood Glucose by Resistin

2004 • 720 citations

Metformin reverses fatty liver disease in obese, leptin-deficient mice

2000 • 680 citations

Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin

2003 • 478 citations

Adiponectin differentially regulates cytokines in porcine macrophages

2004 • 463 citations

Central role of PPARα-dependent hepatic lipid turnover in dietary steatohepatitis in mice

2003 • 461 citations

Lipopolysaccharides in liver injury: molecular mechanisms of Kupffer cell activation

2002 • 460 citations

Adiponectin protects LPS-induced liver injury through modulation of TNF-? in KK-Ay obese mice

2004 • 400 citations

Correlation between Serum Resistin Level and Adiposity in Obese Individuals

2003 • 372 citations

Serum leptin in NASH correlates with hepatic steatosis but not fibrosis: A manifestation of lipotoxicity?

2002 • 368 citations

Hepatitis B virus HBx protein sensitizes cells to apoptotic killing by tumor necrosis factor α

1997 • 302 citations

Sustained peripheral expression of transgene adiponectin offsets the development of diet-induced obesity in rats

2003 • 246 citations

Tumor necrosis factor α, but not Fas, mediates hepatocellular apoptosis in the murine ischemic liver

2002 • 231 citations

Prevention of carbon tetrachloride-induced rat liver injury by soluble tumor necrosis factor receptor

1995 • 184 citations

Does Leptin Play A Role in The Pathogenesis of Human Nonalcoholic Steatohepatitis?

2003 • 145 citations

Increased cytochromeP-450 2E1 expression sensitizes hepatocytes to c-Jun-mediated cell death from TNF-α

2002 • 86 citations