Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin

The pathogenesis of atherosclerosis: a perspective for the 1990s

1993 • 10,730 citations

Paradoxical Decrease of an Adipose-Specific Protein, Adiponectin, in Obesity

1999 • 4,825 citations

A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes

1995 • 3,159 citations

Plasma Concentrations of a Novel, Adipose-Specific Protein, Adiponectin, in Type 2 Diabetic Patients

2000 • 3,142 citations

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

2003 • 3,114 citations

Obesity and the Regulation of Energy Balance

2001 • 2,387 citations

AdipoQ Is a Novel Adipose-specific Gene Dysregulated in Obesity

1996 • 2,229 citations

Novel Modulator for Endothelial Adhesion Molecules

1999 • 2,168 citations

cDNA Cloning and Expression of a Novel Adipose Specific Collagen-like Factor, apM1 (AdiposeMost Abundant Gene Transcript 1)

1996 • 2,082 citations

Diet-induced insulin resistance in mice lacking adiponectin/ACRP30

2002 • 2,081 citations

PPARγ Ligands Increase Expression and Plasma Concentrations of Adiponectin, an Adipose-Derived Protein

2001 • 1,659 citations

The Cellular Basis of Hepatic Fibrosis -- Mechanisms and Treatment Strategies

1993 • 1,444 citations

Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages

2000 • 1,438 citations

The pathogenesis of atherosclerosis

1972 • 1,376 citations

Tumor Necrosis Factor α: A Key Component of the Obesity-Diabetes Link

1994 • 1,302 citations

Circulating Concentrations of the Adipocyte Protein Adiponectin Are Decreased in Parallel With Reduced Insulin Sensitivity During the Progression to Type 2 Diabetes in Rhesus Monkeys

2001 • 1,091 citations

Steatosis accelerates the progression of liver damage of chronic hepatitis C patients and correlates with specific HCV genotype and visceral obesity

2001 • 1,065 citations

TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

1997 • 1,023 citations

Liver fibrosis in overweight patients

2000 • 966 citations

Enhanced expression of PAI–1 in visceral fat: Possible contributor to vascular disease in obeisty

1996 • 886 citations

Tumor Necrosis Factor-α

1997 • 864 citations

Obesity in the new millennium

2000 • 707 citations

Adipocyte-Derived Plasma Protein Adiponectin Acts as a Platelet-Derived Growth Factor-BB–Binding Protein and Regulates Growth Factor–Induced Common Postreceptor Signal in Vascular Smooth Muscle Cell

2002 • 697 citations

Fibrosis in chronic hepatitis C correlates significantly with body mass index and steatosis

1999 • 685 citations

Etiopathogenesis of Nonalcoholic Steatohepatitis

2001 • 678 citations

Excess weight risk factor for alcoholic liver disease

1997 • 633 citations

Adipocyte-specific Gene Expression and Adipogenic Steatosis in the Mouse Liver Due to Peroxisome Proliferator-activated Receptor γ1 (PPARγ1) Overexpression

2002 • 603 citations

Peroxisome Proliferator-activated Receptors and Hepatic Stellate Cell Activation

2000 • 466 citations

Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro

2002 • 436 citations

Leptin receptor–mediated signaling regulates hepatic fibrogenesis and remodeling of extracellular matrix in the rat

2002 • 387 citations

Secretion of Adiponectin and Regulation of apM1 Gene Expression in Human Visceral Adipose Tissue

2001 • 351 citations

Tumor necrosis factor alpha: a key component of the obesity-diabetes link

1994 • 343 citations

Inhibition of transforming growth factorβ prevents progression of liver fibrosis and enhances hepatocyte regeneration in dimethylnitrosamine-treated rats

2000 • 243 citations

Paracrine regulation of fat cell formation in bone marrow cultures via adiponectin and prostaglandins

2002 • 139 citations

Paracrine regulation of fat cell formation in bone marrow cultures via adiponectin and prostaglandins

2002 • 121 citations

Nitrovasodilators inhibit platelet-derived growth factor-induced proliferation and migration of activated human hepatic stellate cells

2000 • 118 citations

Constitutive phosphorylation and nuclear localization of Smad3 are correlated with increased collagen gene transcription in activated hepatic stellate cells

2001 • 113 citations

Leptin enhances the effect of transforming growth factor β in increasing type I collagen formation

2002 • 64 citations

Expression of heat-shock protein 47 in mouse liver

1996 • 50 citations

Angiotensin II stimulates the nuclear translocation of Smad2 and induces PAI-1 mRNA in rat hepatic stellate cells

2003 • 31 citations

<scp>d</scp>-Glucose and insulin stimulate migration and tubular formation of human endothelial cells in vitro

1999 • 16 citations