How finicky is mitochondrial protein import?

Mitochondrial targeting sequences may form amphiphilic helices.

1986 • 1,019 citations

Binding of a specific ligand inhibits import of a purified precursor protein into mitochondria

1986 • 723 citations

A chemically synthesized pre-sequence of an imported mitochondrial protein can form an amphiphilic helix and perturb natural and artificial phospholipid bilayers.

1986 • 493 citations

Transport of proteins into mitochondria: Translocational intermediates spanning contact sites between outer and inner membranes

1985 • 470 citations

How proteins find mitochondria and intramitochondrial compartments

1986 • 302 citations

Distinct steps in the import of ADP/ATP carrier into mitochondria.

1987 • 248 citations

Transport of proteins into mitochondria: a potassium diffusion potential is able to drive the import of ADP/ATP carrier.

1985 • 245 citations

The cleavable pre-sequence of an imported chloroplast protein directs attached polypeptides into yeast mitochondria

1986 • 164 citations

The carboxyl-terminal two-thirds of the ADP/ATP carrier polypeptide contains sufficient information to direct translocation into mitochondria.

1987 • 160 citations

Targeting of bacterial chloramphenicol acetyltransferase to mitochondria in transgenic plants

1987 • 148 citations

Proteinaceous receptors for the import of mitochondrial precursor proteins.

1984 • 148 citations

Mitochondrial protein import: involvement of the mature part of a cleavable precursor protein in the binding to receptor sites.

1987 • 134 citations

A cytosolic protein contains a cryptic mitochondrial targeting signal

1987 • 101 citations

Disruption of the outer membrane restores protein import to trypsin-treated yeast mitochondria.

1987 • 96 citations

High-affinity binding sites involved in the import of porin into mitochondria.

1987 • 92 citations

The yeast F1-ATPase beta subunit precursor contains functionally redundant mitochondrial protein import information.

1987 • 69 citations

Biogenesis of Mitochondrial Energy Transducing Complexes

1987 • 60 citations

Independent mutations at the amino terminus of a protein act as surrogate signals for mitochondrial import.

1987 • 59 citations

Efficient splicing of two yeast mitochondrial introns controlled by a nuclear-encoded maturase.

1987 • 56 citations