Arachidonic acid availability and prostacyclin production by cultured human endothelial cells.

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

1957 • 63,238 citations

Culture of Human Endothelial Cells Derived from Umbilical Veins. IDENTIFICATION BY MORPHOLOGIC AND IMMUNOLOGIC CRITERIA

1973 • 6,904 citations

Preparation of fatty acid methyl esters and dimethylacetals from lipids with boron fluoride–methanol

1964 • 5,892 citations

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

1976 • 3,613 citations

Quantitative analysis of phospholipids by thin-layer chromatography

1964 • 1,414 citations

Prostaglandins and Thromboxanes

1978 • 1,310 citations

Arachidonic Acid Metabolites and the Interactions between Platelets and Blood-Vessel Walls

1979 • 1,158 citations

Production of diglyceride from phosphatidylinositol in activated human platelets.

1979 • 727 citations

Purification of prostaglandin endoperoxide synthetase from bovine vesicular gland microsomes.

1976 • 668 citations

Synthesis of prostaglandin I2 (prostacyclin) by cultured human and bovine endothelial cells.

1977 • 625 citations

Mechanism for irreversible self-deactivation of prostaglandin synthetase.

1976 • 600 citations

Modification of the lowry procedure for the analysis of proteolipid protein

1972 • 563 citations

Purification and characterisation of prostaglandin endoperoxide synthetase from sheep vesicular glands

1977 • 421 citations

The role of lipids in platelet function: with particular reference to the arachidonic acid pathway.

1978 • 364 citations

Further studies on the enzymatic conversion of prostaglandin endoperoxide into prostacyclin by porcine aorta microsomes

1978 • 306 citations

Thrombin-induced hydrolysis of phosphatidylinositol in human platelets.

1980 • 244 citations

Formation of lysophosphatidylcholine by human platelets in response to thrombin. Support for the phospholipase A2 pathway for the liberation of arachidonic acid.

1981 • 217 citations

Enzymatic conversion of prostaglandin endoperoxide H2 and arachidonic acid to prostacyclin by cultured human endothelial cells.

1978 • 196 citations

Effect of Aspirin on Thrombin-Induced Adherence of Platelets to Cultured Cells from the Blood Vessel Wall

1978 • 184 citations

Utilization of arachidonic and linoleic acids by cultured human endothelial cells.

1981 • 175 citations

Effect of fatty acid modification on prostacyclin production by cultured human endothelial cells.

1980 • 155 citations

Modification of the fatty acid composition of cultured human fibroblasts.

1979 • 141 citations

Role of Ca2+ and cyclic AMP in the regulation of the production of prostacyclin by the vascular endothelium.

1982 • 140 citations

Use of a radioimmunoassay to study thrombin-induced release of PGI2 from cultured endothelium

1979 • 123 citations

Serum stimulation of phospholipase A2 and prostaglandin release in 3T3 cells is associated with platelet-derived growth-promoting activity.

1980 • 104 citations

Albumins stabilize prostaglandin I2

1980 • 88 citations

Antibodies which antagonise the effects of prostacyclin

1978 • 70 citations

Linoleic acid metabolism and prostaglandin production by cultured bovine pulmonary artery endothelial cells.

1982 • 68 citations

Tranylcypromine and 15-hydroperoxyarachidonate affect arachidonic acid release in addition to inhibition of prostacyclin synthesis in calf aortic endothelial cells.

1980 • 64 citations

Stimulation of human foreskin fibroblast adenosine 3‘:5‘-cyclic monophosphate levels by prostacyclin (prostaglandin I2).

1979 • 51 citations

Effect of three nonsteroidal anti-inflammatory agents on platelet function and prostaglandin synthesis in vitro

1978 • 49 citations

An improved assay with 4-(2-thiazolylazo)-resorcinol for non-esterified fatty acids in biological fluids

1980 • 47 citations

Prostacyclin biosynthesis in vascular endothelium is not inhibited by cyclic AMP. Studies with 3-isobutyl-1-methylxanthine and forskolin

1982 • 36 citations

Effect of fatty acid modification on prostaglandin production by cultured 3T3 cells.

1982 • 29 citations

Essential fatty acid availability and prostacyclin production by cultured human endothelial cells

1981 • 22 citations

On the Mechanism of Elevated Prostaglandin E₂ Production in 3T3 Fibroblasts Transformed by Polyoma Virus

1980 • 12 citations