Further studies on the enzymatic conversion of prostaglandin endoperoxide into prostacyclin by porcine aorta microsomes

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

1976 • 3,613 citations

Arterial walls are protected against deposition of platelet thrombi by a substance (prostaglandin X) which they make from prostaglandin endoperoxides

1976 • 1,012 citations

Arterial walls generate from prostaglandin endoperoxides a substance (prostaglandin X) which relaxes strips of mesenteric and coeliac arteries and inhibits platelet aggregation

1976 • 956 citations

HUMAN ARTERIAL AND VENOUS TISSUES GENERATE PROSTACYCLIN (PROSTAGLANDIN X), A POTENT INHIBITOR OF PLATELET AGGREGATION

1977 • 886 citations

The chemical structure of prostaglandin X (prostacyclin)

1976 • 729 citations

A lipid peroxide inhibits the enzyme in blood vessel microsomes that generates from prostaglandin endoperoxides the substance (prostaglandin X) which prevents platelet aggregation

1976 • 606 citations

Intracellular mechanisms for the decomposition of a lipid peroxide. I. Decomposition of a lipid peroxide by metal ions, heme compounds, and nucleophiles

1969 • 353 citations

Quantitative determination of prostaglandins and malondialdehyde formed by the arachidonate oxygenase (prostaglandin synthetase) system of bovine seminal vesicle

1973 • 275 citations

Preparation and purification of lipid hydroperoxides from arachidonic and γ‐linolenic acids

1976 • 216 citations

Synthesis of 6-keto-PGF1α by ram seminal vesicle microsomes

1977 • 128 citations

Lipids of human atheroma Part 5. The occurrence of a new group of polar sterol esters in various stages of human atherosclerosis

1971 • 106 citations

Application of interferometry to reaction kinetics: hydrolysis of ethyl acetate

1969 • 96 citations

Lipids of human atheroma. 8. Oxidised derivatives of cholesteryl linoleate.

1973 • 95 citations

Prostaglandins H1 and H2. Convenient biochemical synthesis and isolation. Further biological and spectroscopic characterization

1977 • 80 citations

Lipids of human atheroma

1973 • 62 citations

Linoleate oxidation products and cardiovascular lesions

1974 • 37 citations

The inactivation of isocitrate dehydrogenase by a lipid peroxide

1971 • 32 citations