Proteolytic and non-proteolytic activation of human neutrophil progelatinase B

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Calculation of protein extinction coefficients from amino acid sequence data

1989 • 5,198 citations

Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes.

1987 • 5,066 citations

Matrix metalloproteinases and their inhibitors in connective tissue remodeling

1991 • 3,309 citations

Matrix Metalloproteinases: A Review

1993 • 2,998 citations

Ultrasensitive Stain for Proteins in Polyacrylamide Gels Shows Regional Variation in Cerebrospinal Fluid Proteins

1981 • 2,972 citations

Tumor invasion and metastases--role of the extracellular matrix: Rhoads Memorial Award lecture.

1986 • 1,408 citations

The matrix‐degrading metalloproteinases

1992 • 1,383 citations

Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase

1993 • 1,226 citations

SV40-transformed Human Lung Fibroblasts Secrete a 92-kDa Type IV Collagenase Which Is Identical to That Secreted by Normal Human Macrophages

1989 • 1,122 citations

Chapter 1: Interferons (IFNs)

1986 • 793 citations

Endogenous Activation of Latent Collagenase by Rheumatoid Synovial Cells

1977 • 686 citations

Biochemical and immunological characterization of the secreted forms of human neutrophil gelatinase.

1985 • 625 citations

Matrix metalloproteinase 3 (stromelysin) activates the precursor for the human matrix metalloproteinase 9.

1992 • 620 citations

Interaction of 92-kDa type IV collagenase with the tissue inhibitor of metalloproteinases prevents dimerization, complex formation with interstitial collagenase, and activation of the proenzyme with stromelysin.

1992 • 519 citations

Matrix metalloproteinase 9 (92-kDa gelatinase/type IV collagenase) from HT 1080 human fibrosarcoma cells. Purification and activation of the precursor and enzymic properties.

1992 • 502 citations

Neutral metalloproteinases produced by human mononuclear phagocytes. Enzyme profile, regulation, and expression during cellular development.

1990 • 459 citations

Cellular Biology and Biochemical Mechanism of Bone Resorption

1988 • 383 citations

Reproducible high yield sequencing of proteins electrophoretically separated and transferred to an inert support.

1988 • 375 citations

Type IV collagenase(s) and TIMPs modulate endothelial cell morphogenesis in vitro

1993 • 296 citations

Expression and localization of matrix‐degrading metalloproteinases during colorectal tumorigenesis

1994 • 256 citations

Concanavalin A produces a matrix-degradative phenotype in human fibroblasts. Induction and endogenous activation of collagenase, 72-kDa gelatinase, and Pump-1 is accompanied by the suppression of the tissue inhibitor of matrix metalloproteinases.

1990 • 235 citations

Expression of a metalloproteinase that degrades native type V collagen and denatured collagens by cultured human alveolar macrophages.

1987 • 235 citations

A 25 kDa α₂‐microglobulin‐related protein is a component of the 125 kDa form of human gelatinase

1992 • 226 citations

Proteinases and extracellular remodeling

1989 • 224 citations

Interleukin 4 inhibition of prostaglandin E2 synthesis blocks interstitial collagenase and 92-kDa type IV collagenase/gelatinase production by human monocytes.

1992 • 204 citations

Partial purification of collagenase and gelatinase from human polymorphonuclear leucocytes. Analysis of their actions on soluble and insoluble collagens

1982 • 203 citations

Purification and characterization of matrix metalloproteinase 9 from U937 monocytic leukaemia and HT1080 fibrosarcoma cells

1992 • 191 citations

The latent collagenase and gelatinase of human polymorphonuclear neutrophil leucocytes

1980 • 168 citations

Presence of a gelatin-specific proteinase and its latent form in human leucocytes

1974 • 127 citations

Interleukin-1 beta and transforming growth factor-alpha/epidermal growth factor induce expression of M(r) 95,000 type IV collagenase/gelatinase and interstitial fibroblast-type collagenase by rat mucosal keratinocytes.

1993 • 126 citations

The matrix metalloprotease matrilysin (PUMP) is expressed in developing human mononuclear phagocytes.

1992 • 121 citations

Characterization and activation of procollagenase from human polymorphonuclear leucocytes

1990 • 101 citations

Cell type-specific regulation of SL-1 and SL-2 genes. Induction of the SL-2 gene but not the SL-1 gene by human keratinocytes in response to cytokines and phorbolesters

1993 • 97 citations

Anti‐integrin antibodies induce type IV collagenase expression in keratinocytes

1993 • 94 citations

Characterization of 58-kilodalton human neutrophil collagenase: comparison with human fibroblast collagenase

1990 • 93 citations

Monoclonal antibodies to human fibroblast procollagenase. Inhibition of enzymatic activity, affinity purification of the enzyme, and evidence for clustering of epitopes in the amino-terminal end of the activated enzyme

1988 • 91 citations

Characteristics of a 95-kDa matrix metalloproteinase produced by mammary carcinoma cells

1991 • 83 citations

Structure and expression of neutrophil gelatinase cDNA. Identity with type IV collagenase from HT1080 cells.

1992 • 80 citations

Different effects of hypochlorous acid on human neutrophil metalloproteinases: Activation of collagenase and inactivation of collagenase and gelatinase

1992 • 65 citations

Human macrophages synthesize and secrete a major 95,000-dalton gelatin-binding protein distinct from fibronectin.

1982 • 59 citations

Identification of Type IV Collagenase in Rat Testicular Cell Culture: Influence of Peritubular-Sertoli Cell Interactions1

1990 • 48 citations

Purification to homogeneity of latent and active 58-kilodalton forms of human neutrophil collagenase

1990 • 43 citations

Accurate, quantitative assays for the hydrolysis of soluble type I, II, and III 3H-acetylated collagens by bacterial and tissue collagenases

1986 • 34 citations

A latent gelatin specific proteinase of human leucocytes and its activation

1979 • 33 citations

Mercurial activation of human PMN leucocyte type IV procollagenase (gelatinase)

1992 • 31 citations

Production, Purification, and Characterization of Human Matrilysin (PUMP) from Recombinant Chinese Hamster Ovary Cells

1994 • 24 citations

Tumorigenicity of mouse T lymphoma cells is controlled by the level of major histocompatibility complex class I H-2Kk antigens

1994 • 15 citations