Hybrid resistance and the Ly-49 family of natural killer cell receptors.

Biology of Natural Killer Cells

1989 • 2,970 citations

RAG-1-deficient mice have no mature B and T lymphocytes

1992 • 2,859 citations

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1992 • 2,618 citations

MHC class I alloantigen specificity of Ly-49+ IL-2-activated natural killer cells

1992 • 805 citations

The Ly-49 and NKR-P1 Gene Families Encoding Lectin-Like Receptors on Natural Killer Cells: The NK Gene Complex

1993 • 465 citations

Rejection of class I MHC-deficient haemopoietic cells by irradiated MHC-matched mice

1991 • 419 citations

Natural killer cells: definition of a cell type rather than a function

1987 • 385 citations

NKB1: a natural killer cell receptor involved in the recognition of polymorphic HLA-B molecules.

1994 • 343 citations

Natural killer cell receptors

1995 • 314 citations

Recognition of beta 2-microglobulin-negative (beta 2m-) T-cell blasts by natural killer cells from normal but not from beta 2m- mice: nonresponsiveness controlled by beta 2m- bone marrow in chimeric mice.

1991 • 269 citations

A population of early fetal thymocytes expressing FcγRIIIII contains precursors of T lymphocytes and natural killer cells

1992 • 264 citations

Oligosaccharide ligands for NKR-P1 protein activate NK cells and cytotoxicity

1994 • 256 citations

Prevention of Allogeneic Bone Marrow Graft Rejection by H-2 Transgene in Donor Mice

1989 • 218 citations

Murine Natural Killer Cells and Marrow Graft Rejection

1992 • 217 citations

Cloning and functional characteristics of murine large granular lymphocyte-1: a member of the Ly-49 gene family (Ly-49G2)

1995 • 212 citations

Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles.

1994 • 193 citations

Ly-49 multigene family expressed by IL-2-activated NK cells.

1994 • 180 citations

Binding of diverse peptides to MHC class I molecules inhibits target cell lysis by activated natural killer cells

1995 • 180 citations

YAC-1 MHC class I variants reveal an association between decreased NK sensitivity and increased H-2 expression after interferon treatment or in vivo passage.

1985 • 171 citations

Expression of different members of the Ly-49 gene family defines distinct natural killer cell subsets and cell adhesion properties.

1994 • 169 citations

Ly-49 mediates EL4 lymphoma adhesion to isolated class I major histocompatibility complex molecules.

1994 • 162 citations

A natural killer cell receptor specific for a major histocompatibility complex class I molecule.

1994 • 157 citations

Natural killer cell receptors

1998 • 148 citations

Identification of a subset of murine natural killer cells that mediates rejection of Hh-1d but not Hh-1b bone marrow grafts.

1989 • 144 citations

Chromosomal location of the Ly-49 (A1, YE1/48) multigene family. Genetic association with the NK 1.1 antigen.

1990 • 144 citations

Altered phenotype and function of natural killer cells expressing the major histocompatibility complex receptor Ly-49 in mice transgenic for its ligand.

1995 • 134 citations

Ly-49 multigene family. New members of a superfamily of type II membrane proteins with lectin-like domains.

1991 • 132 citations

Class I-induced resistance to natural killing: identification of nonpermissive residues in HLA-A2.

1991 • 128 citations

Host MHC class I molecules modulate in vivo expression of a NK cell receptor.

1994 • 119 citations

Ly-49A, a receptor for H-2Dd, has a functional carbohydrate recognition domain

1994 • 115 citations

Transplantable progenitors of natural killer cells are distinct from those of T and B lymphocytes.

1986 • 107 citations

Human natural killer cell committed thymocytes and their relation to the T cell lineage.

1993 • 107 citations

Hematopoietic cells and radioresistant host elements influence natural killer cell differentiation.

1993 • 103 citations

Natural killer cell receptors specific for major histocompatibility complex class I molecules.

1995 • 88 citations

Recognition of major histocompatibility complex class I antigens by natural killer cells.

1994 • 84 citations

Control of rat natural killer cell-mediated allorecognition by a major histocompatibility complex region encoding nonclassical class I antigens.

1994 • 79 citations

ROLE OF TARGET HISTOCOMPATIBILITY ANTIGENS IN REGULATION OF NATURAL KILLER ACTIVITY: A REEVALUATION AND A HYPOTHESIS11Based on a doctoral thesis at The Karolinska Institute, supported by grants from the Karolinska Institute, The Swedish Cancer Society, The National Cancer Institute (US DHEW) and The Engwall Foundation.

1985 • 76 citations

Hybrid resistance in vitro. Possible role of both class I MHC and self peptides in determining the level of target cell sensitivity.

1992 • 71 citations

Ly-49-independent natural killer (NK) cell specificity revealed by NK cell clones derived from p53-deficient mice.

1995 • 53 citations

Regulation of hematopoiesis in vitro by alloreactive natural killer cell clones.

1993 • 50 citations

Bone marrow cell transplants involving intra-H-2 recombinant inbred mouse strains. Evidence that hemopoietic histocompatibility-1 (Hh-1) genes are distinct from H-2D or H-2L.

1988 • 40 citations

Natural killer cells: definition of a cell type rather than a function

1987 • 19 citations

Murine Natural Killer Cells And Marrow Graft Rejection

1992 • 18 citations

Recognition of beta 2-microglobulin-negative (beta 2m-) T-cell blasts by natural killer cells from normal but not from beta 2m- mice: nonresponsiveness controlled by beta 2m- bone marrow in chimeric mice.

1991 • 9 citations