Natural killer cell receptors specific for major histocompatibility complex class I molecules.

Biology of Natural Killer Cells

1989 • 2,970 citations

RAG-1-deficient mice have no mature B and T lymphocytes

1992 • 2,859 citations

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1992 • 2,618 citations

In search of the ‘missing self’: MHC molecules and NK cell recognition

1990 • 2,600 citations

Selective rejection of H–2-deficient lymphoma variants suggests alternative immune defence strategy

1986 • 2,102 citations

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

1994 • 1,772 citations

A Class I Antigen, HLA-G, Expressed in Human Trophoblasts

1990 • 1,417 citations

Severe Herpesvirus Infections in an Adolescent without Natural Killer Cells

1989 • 1,251 citations

The ikaros gene is required for the development of all lymphoid lineages

1994 • 976 citations

MHC class I alloantigen specificity of Ly-49+ IL-2-activated natural killer cells

1992 • 805 citations

Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist.

1993 • 792 citations

NK Cells and Other Natural Effector Cells

1982 • 624 citations

Natural killer cells are a source of interferon gamma that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in mice.

1993 • 612 citations

P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities.

1993 • 537 citations

The Bw4 public epitope of HLA-B molecules confers reactivity with natural killer cell clones that express NKB1, a putative HLA receptor.

1995 • 507 citations

CD21 is a ligand for CD23 and regulates IgE production

1992 • 479 citations

MHC Class I Deficiency: Susceptibility to Natural Killer (NK) Cells and Impaired NK Activity

1991 • 474 citations

The Ly-49 and NKR-P1 Gene Families Encoding Lectin-Like Receptors on Natural Killer Cells: The NK Gene Complex

1993 • 465 citations

DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells.

1991 • 430 citations

Rejection of class I MHC-deficient haemopoietic cells by irradiated MHC-matched mice

1991 • 419 citations

Co-association of CD3ζ with a receptor (CD16) for IgG Fc on human natural killer cells

1989 • 412 citations

Natural killer cells: definition of a cell type rather than a function

1987 • 385 citations

Natural killer (NK) cells are present in mice with severe combined immunodeficiency (scid).

1985 • 362 citations

NKB1: a natural killer cell receptor involved in the recognition of polymorphic HLA-B molecules.

1994 • 343 citations

The role of natural killer cells in innate resistance to infection

1993 • 330 citations

Peptide Specificity in the Recognition of MHC Class I by Natural Killer Cell Clones

1995 • 308 citations

Molecular Components of T-Cell Recognition

1992 • 304 citations

Cytotoxic cells induced during lymphocytic choriomeningitis virus infection of mice. I. Characterization of natural killer cell induction

1978 • 296 citations

Molecular cloning, expression, and chromosomal localization of the human earliest lymphocyte activation antigen AIM/CD69, a new member of the C-type animal lectin superfamily of signal-transmitting receptors.

1993 • 280 citations

Recognition of beta 2-microglobulin-negative (beta 2m-) T-cell blasts by natural killer cells from normal but not from beta 2m- mice: nonresponsiveness controlled by beta 2m- bone marrow in chimeric mice.

1991 • 269 citations

A population of early fetal thymocytes expressing FcγRIIIII contains precursors of T lymphocytes and natural killer cells

1992 • 264 citations

Oligosaccharide ligands for NKR-P1 protein activate NK cells and cytotoxicity

1994 • 256 citations

Polymorphism in the α3 domain of HLA-A molecules affects binding to CD8

1989 • 247 citations

Generation of Allospecific Natural Killer Cells by Stimulation Across a Polymorphism of HLA-C

1993 • 241 citations

Reversal of natural killing susceptibility in target cells expressing transfected class I HLA genes.

1989 • 241 citations

Prevention of Allogeneic Bone Marrow Graft Rejection by H-2 Transgene in Donor Mice

1989 • 218 citations

Involvement of HLA class I alleles in natural killer (NK) cell-specific functions: expression of HLA-Cw3 confers selective protection from lysis by alloreactive NK clones displaying a defined specificity (specificity 2).

1992 • 218 citations

Murine Natural Killer Cells and Marrow Graft Rejection

1992 • 217 citations

"E3/19K" protein of adenovirus type 2 inhibits lysis of cytolytic T lymphocytes by blocking cell-surface expression of histocompatibility class I antigens.

1987 • 215 citations

Substitution at residue 227 of H–2 class I molecules abrogates recognition by CD8-dependent, but not CD8-independent, cytotoxic T lymphocytes

1989 • 198 citations

Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles.

1994 • 193 citations

Evidence of a natural killer (NK) cell repertoire for (allo) antigen recognition: definition of five distinct NK-determined allospecificities in humans.

1992 • 190 citations

Lymphokine-activated killer cells, natural killer cells and cytokines

1991 • 182 citations

Ly-49 multigene family expressed by IL-2-activated NK cells.

1994 • 180 citations

Binding of diverse peptides to MHC class I molecules inhibits target cell lysis by activated natural killer cells

1995 • 180 citations

Specificity of HLA class I antigen recognition by human NK clones: evidence for clonal heterogeneity, protection by self and non-self alleles, and influence of the target cell type.

1993 • 178 citations

Human natural killer cells isolated from peripheral blood do not rearrange T cell antigen receptor beta chain genes.

1986 • 178 citations

YAC-1 MHC class I variants reveal an association between decreased NK sensitivity and increased H-2 expression after interferon treatment or in vivo passage.

1985 • 171 citations

Recognition by CD8 on cytotoxic T lymphocytes is ablated by several substitutions in the class I alpha 3 domain: CD8 and the T-cell receptor recognize the same class I molecule.

1990 • 164 citations

Ly-49 mediates EL4 lymphoma adhesion to isolated class I major histocompatibility complex molecules.

1994 • 162 citations

A natural killer cell receptor specific for a major histocompatibility complex class I molecule.

1994 • 157 citations

Alloantigen recognition by two human natural killer cell clones is associated with HLA-C or a closely linked gene.

1992 • 157 citations

cDNA cloning of mouse NKR-P1 and genetic linkage with LY-49. Identification of a natural killer cell gene complex on mouse chromosome 6.

1991 • 153 citations

Expression of cytoplasmic CD3 epsilon proteins in activated human adult natural killer (NK) cells and CD3 gamma, delta, epsilon complexes in fetal NK cells. Implications for the relationship of NK and T lymphocytes.

1992 • 147 citations

Identification of a subset of murine natural killer cells that mediates rejection of Hh-1d but not Hh-1b bone marrow grafts.

1989 • 144 citations

The mouse CD69 gene. Structure, expression, and mapping to the NK gene complex.

1994 • 135 citations

Ly-49 multigene family. New members of a superfamily of type II membrane proteins with lectin-like domains.

1991 • 132 citations

Class I-induced resistance to natural killing: identification of nonpermissive residues in HLA-A2.

1991 • 128 citations

Recognition structures on natural killer cells

1993 • 123 citations

Host MHC class I molecules modulate in vivo expression of a NK cell receptor.

1994 • 119 citations

Mechanisms of Cytotoxicity by NK Cells

1985 • 117 citations

Ly-49A, a receptor for H-2Dd, has a functional carbohydrate recognition domain

1994 • 115 citations

Increased resistance to non-MHC-restricted cytotoxicity related to HLA A, B expression. Direct demonstration using beta 2-microglobulin-transfected Daudi cells.

1988 • 106 citations

Hematopoietic cells and radioresistant host elements influence natural killer cell differentiation.

1993 • 103 citations

Glycopeptides bind MHC molecules and elicit specific T cell responses.

1993 • 98 citations

Control of rat natural killer cell-mediated allorecognition by a major histocompatibility complex region encoding nonclassical class I antigens.

1994 • 79 citations

Peptide-induced modulation of target cell sensitivity to natural killing.

1992 • 71 citations

Coexpression of two functionally independent p58 inhibitory receptors in human natural killer cell clones results in the inability to kill all normal allogeneic target cells.

1995 • 65 citations

A novel functional cell surface dimer (Kp43) expressed by natural killer cells and gamma/delta TCR+ T lymphocytes. II. Modulation of natural killer cytotoxicity by anti-Kp43 monoclonal antibody.

1991 • 61 citations

Natural killer activity in cloned cytotoxic T lymphocytes: regulation by interleukin 2, interferon, and specific antigen.

1985 • 58 citations

MHC class I expression on tumor targets inhibits natural killer cell-mediated cytotoxicity without interfering with target recognition.

1993 • 57 citations

Granulated Metrial Gland Cells: Pregnancy Specific Leukocytes?

1991 • 53 citations

Effect of class I MHC binding peptides on recognition by natural killer cells.

1992 • 38 citations

Natural killer (NK) cell subsets in the mouse. NK-1.1+/LGL-1+ cells restricted to lysing NK targets, whereas NK-1.1+/LGL-1- cells generate lymphokine-activated killer cells.

1990 • 31 citations

LGL-1: a potential triggering molecule on murine NK cells

1994 • 19 citations