Natural killer cell receptors

HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C

1998 • 2,114 citations

LAT

1998 • 1,251 citations

Human Diversity in Killer Cell Inhibitory Receptor Genes

1997 • 1,052 citations

HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A

1998 • 998 citations

A Common Inhibitory Receptor for Major Histocompatibility Complex Class I Molecules on Human Lymphoid and Myelomonocytic Cells

1997 • 933 citations

Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells

1998 • 892 citations

Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor FeγRIIB

1996 • 770 citations

Functionally and Structurally Distinct NK Cell Receptor Repertoires in the Peripheral Blood of Two Human Donors

1997 • 735 citations

Recognition of Human Histocompatibility Leukocyte Antigen (HLA)-E Complexed with HLA Class I Signal Sequence–derived Peptides by CD94/NKG2 Confers Protection from Natural Killer Cell–mediated Lysis

1998 • 706 citations

A Novel Immunoglobulin Superfamily Receptor for Cellular and Viral MHC Class I Molecules

1997 • 681 citations

A family of proteins that inhibit signalling through tyrosine kinase receptors

1997 • 648 citations

Deletion of SHIP or SHP-1 Reveals Two Distinct Pathways for Inhibitory Signaling

1997 • 505 citations

HLA-E Surface Expression Depends on Binding of TAP-Dependent Peptides Derived from Certain HLA Class I Signal Sequences

1998 • 495 citations

Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells.

1995 • 446 citations

Human natural killer cell receptors involved in MHC class I recognition are disulfide-linked heterodimers of CD94 and NKG2 subunits.

1996 • 441 citations

DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells.

1991 • 430 citations

A Novel Inhibitory Receptor (ILT3) Expressed on Monocytes, Macrophages, and Dendritic Cells Involved in Antigen Processing

1997 • 426 citations

LAIR-1, a Novel Inhibitory Receptor Expressed on Human Mononuclear Leukocytes

1997 • 386 citations

Regulation of Experimental Autoimmune Encephalomyelitis by Natural Killer (NK) Cells

1997 • 360 citations

Sequential Involvement of Lck and SHP-1 with MHC-Recognizing Receptors on NK Cells Inhibits FcR-Initiated Tyrosine Kinase Activation

1996 • 341 citations

Protection from lysis by natural killer cells of group 1 and 2 specificity is mediated by residue 80 in human histocompatibility leukocyte antigen C alleles and also occurs with empty major histocompatibility complex molecules.

1996 • 340 citations

The class I MHC homologue of human cytomegalovirus inhibits attack by natural killer cells

1997 • 327 citations

A novel pair of immunoglobulin-like receptors expressed by B cells and myeloid cells

1997 • 325 citations

Inhibition of natural killer cells by a cytomegalovirus MHC class I homologue in vivo

1997 • 305 citations

Cloning of novel immunoglobulin superfamily receptors expressed on human myeloid and lymphoid cells: Structural evidence for new stimulatory and inhibitory pathways

1997 • 298 citations

Signal Transduction during Natural Killer Cell Activation: Inside the Mind of a Killer

1997 • 293 citations

TAP- and tapasin-dependent HLA-E surface expression correlates with the binding of an MHC class I leader peptide

1998 • 275 citations

Human killer cell activatory receptors for MHC class I molecules are included in a multimeric complex expressed by natural killer cells.

1997 • 260 citations

Natural Killer Cells: From No Receptors to Too Many

1997 • 236 citations

Natural killer cell cytolytic activity is inhibited by NKG2-A and activated by NKG2-C.

1997 • 229 citations

A single amino acid in the p58 killer cell inhibitory receptor controls the ability of natural killer cells to discriminate between the two groups of HLA-C allotypes.

1997 • 224 citations

Mouse Ly-49A Interrupts Early Signaling Events in Natural Killer Cell Cytotoxicity and Functionally Associates with the SHP-1 Tyrosine Phosphatase

1997 • 216 citations

The Ly-49D Receptor Activates Murine Natural Killer Cells

1996 • 213 citations

Cloning and functional characteristics of murine large granular lymphocyte-1: a member of the Ly-49 gene family (Ly-49G2)

1995 • 212 citations

The Direct Binding of a p58 Killer Cell Inhibitory Receptor to Human Histocompatibility Leukocyte Antigen (HLA)-Cw4 Exhibits Peptide Selectivity

1997 • 208 citations

Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles.

1994 • 193 citations

Allelic exclusion of Ly49-family genes encoding class I MHC-specific receptors on NK cells

1995 • 188 citations

CD94 and a Novel Associated Protein (94AP) Form a NK Cell Receptor Involved in the Recognition of HLA-A, HLA-B, and HLA-C Allotypes

1996 • 187 citations

A new human gene complex encoding the killer cell inhibitory receptors and related monocyte/macrophage receptors

1997 • 183 citations

Ly-49 multigene family expressed by IL-2-activated NK cells.

1994 • 180 citations

Binding of diverse peptides to MHC class I molecules inhibits target cell lysis by activated natural killer cells

1995 • 180 citations

Molecular Cloning of a Novel Murine Cell-surface Glycoprotein Homologous to Killer Cell Inhibitory Receptors

1997 • 173 citations

Structure of the inhibitory receptor for human natural killer cells resembles haematopoietic receptors

1997 • 168 citations

Association with FcRγ Is Essential for Activation Signal through NKR-P1 (CD161) in Natural Killer (NK) Cells and NK1.1+ T Cells

1997 • 159 citations

The natural killer gene complex: a genetic basis for understanding natural killer cell function and innate immunity

1997 • 154 citations

Molecular Cloning of the cDNA Encoding pp36, a Tyrosine-phosphorylated Adaptor Protein Selectively Expressed by T Cells and Natural Killer Cells

1998 • 151 citations

Functional Role for Syk Tyrosine Kinase in Natural Killer Cell–mediated Natural Cytotoxicity

1997 • 147 citations

Natural Killer Cell Tolerance in Mice with Mosaic Expression of Major Histocompatibility Complex Class I Transgene

1997 • 146 citations

A p70 killer cell inhibitory receptor specific for several HLA-B allotypes discriminates among peptides bound to HLA-B*2705.

1996 • 140 citations

CD94 functions as a natural killer cell inhibitory receptor for different HLA class I alleles: identification of the inhibitory form of CD94 by the use of novel monoclonal antibodies

1996 • 133 citations

Killer Cell Inhibitory Receptor Recognition of Human Leukocyte Antigen (HLA) Class I Blocks Formation of a pp36/PLC-γ Signaling Complex in Human Natural Killer (NK) Cells

1996 • 133 citations

Altered expression of Ly49 inhibitory receptors on natural killer cells from MHC class I-deficient mice.

1997 • 131 citations

MurineNkg2dandCd94are clustered within the natural killer complex and are expressed independently in natural killer cells

1998 • 128 citations

A 2-Mb YAC Contig and Physical Map of the Natural Killer Gene Complex on Mouse Chromosome 6

1997 • 127 citations

NKR-P1A is a target-specific receptor that activates natural killer cell cytotoxicity.

1995 • 125 citations

Recognition structures on natural killer cells

1993 • 123 citations

Specific engagement of the CD94/NKG2-A killer inhibitory receptor by the HLA-E class Ib molecule induces SHP-1 phosphatase recruitment to tyrosine-phosphorylated NKG2-A: evidence for receptor function in heterologous transfectants

1998 • 122 citations

Cloning of a mouse homolog of CD94 extends the family of C‐type lectins on murine natural killer cells

1997 • 122 citations

Transgenic expression of the Ly49A natural killer cell receptor confers class I major histocompatibility complex (MHC)-specific inhibition and prevents bone marrow allograft rejection.

1996 • 120 citations

Heterogeneity Among Ly-49C Natural Killer (NK) Cells: Characterization of Highly Related Receptors with Differing Functions and Expression Patterns

1996 • 119 citations

Ly-49A, a receptor for H-2Dd, has a functional carbohydrate recognition domain

1994 • 115 citations

Peptides isolated from HLA-Cw*0304 confer different degrees of protection from natural killer cell-mediated lysis

1997 • 107 citations

The Binding Site of NK Receptors on HLA-C Molecules

1997 • 98 citations

Ly49A Transgenic Mice Provide Evidence for a Major Histocompatibility Complex–dependent Education Process in Natural Killer Cell Development

1997 • 97 citations

Cloning and characterization of 5E6(Ly-49C), a receptor molecule expressed on a subset of murine natural killer cells.

1995 • 96 citations

Negative Signaling Pathways of the Killer Cell Inhibitory Receptor and FcγRIIb1 Require Distinct Phosphatases

1997 • 94 citations

The natural killer cell receptor Ly-49A recognizes a peptide-induced conformational determinant on its major histocompatibility complex class I ligand.

1996 • 94 citations

Enhancement of Class II-Restricted T cell Responses by Costimulatory NK Receptors for Class I MHC Proteins

1996 • 89 citations

What Goes Up Must Come Down: The Emerging Spectrum of Inhibitory Receptors

1997 • 79 citations

Molecular cloning of gp49, a cell-surface antigen that is preferentially expressed by mouse mast cell progenitors and is a new member of the immunoglobulin superfamily

1991 • 79 citations

Self and viral peptides can initiate lysis by autologous natural killer cells

1997 • 79 citations

The Lectin-Like NK Cell Receptor Ly-49A Recognizes a Carbohydrate-Independent Epitope on Its MHC Class I Ligand

1998 • 79 citations

Molecular Mechanisms in Cell-Mediated Cytotoxicity

1997 • 74 citations

Molecular characterization of a gene in the rat homologous to human CD94

1997 • 65 citations

Expression of the Ly49A gene in murine natural killer cell clones is predominantly but not exclusively mono‐allelic

1997 • 57 citations

Cloning of NKG2‐F, a new member of the NKG2 family of human natural killer cell receptor genes

1997 • 55 citations

Two genes in the rat homologous to human NKG2

1998 • 49 citations

The mother–child union: The case of missing-self and protection of the fetus

1997 • 33 citations

Location‐specific regulation of transgenic Ly49A receptors by major histocompatibility complex class I molecules

1997 • 33 citations

The α2 Domain of H-2Dd Restricts the Allelic Specificity of the Murine NK Cell Inhibitory Receptor Ly-49A

1998 • 31 citations