Ly-49-independent natural killer (NK) cell specificity revealed by NK cell clones derived from p53-deficient mice.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1992 • 4,648 citations

Biology of Natural Killer Cells

1989 • 2,970 citations

Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene

1985 • 1,836 citations

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

1992 • 1,358 citations

Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life.

1988 • 1,140 citations

β2-Microglobulin deficient mice lack CD4−8+ cytolytic T cells

1990 • 997 citations

MHC class I alloantigen specificity of Ly-49+ IL-2-activated natural killer cells

1992 • 805 citations

Sequence relationships between putative T-cell receptor polypeptides and immunoglobulins

1984 • 719 citations

NK Cells and Other Natural Effector Cells

1982 • 624 citations

A third type of murine T-cell receptor gene

1984 • 491 citations

A new T-cell receptor gene located within the alpha locus and expressed early in T-cell differentiation

1987 • 483 citations

MHC Class I Deficiency: Susceptibility to Natural Killer (NK) Cells and Impaired NK Activity

1991 • 474 citations

In vitro growth characteristics of embryo fibroblasts isolated from p53-deficient mice.

1993 • 471 citations

Co-association of CD3ζ with a receptor (CD16) for IgG Fc on human natural killer cells

1989 • 412 citations

Natural killer cells: definition of a cell type rather than a function

1987 • 385 citations

Monoclonal antibody to a triggering structure expressed on rat natural killer cells and adherent lymphokine-activated killer cells.

1989 • 365 citations

NKB1: a natural killer cell receptor involved in the recognition of polymorphic HLA-B molecules.

1994 • 343 citations

Restoration of antigen presentation to the mutant cell line RMA-S by an MHC-linked transporter

1991 • 329 citations

Activating Mutations for Transformation by p53 Produce a Gene Product That Forms an hsc70-p53 Complex with an Altered Half-Life

1988 • 298 citations

A novel function-associated molecule related to non-MHC-restricted cytotoxicity mediated by activated natural killer cells and T cells.

1993 • 283 citations

Recognition of beta 2-microglobulin-negative (beta 2m-) T-cell blasts by natural killer cells from normal but not from beta 2m- mice: nonresponsiveness controlled by beta 2m- bone marrow in chimeric mice.

1991 • 269 citations

Involvement of HLA class I alleles in natural killer (NK) cell-specific functions: expression of HLA-Cw3 confers selective protection from lysis by alloreactive NK clones displaying a defined specificity (specificity 2).

1992 • 218 citations

CD3-negative natural killer cells express ε TCR as part of a novel molecular complex

1989 • 210 citations

Cloning and characterization of the 2B4 gene encoding a molecule associated with non-MHC-restricted killing mediated by activated natural killer cells and T cells.

1993 • 206 citations

Unusual T cell populations in adult murine bone marrow. Prevalence of CD3+CD4-CD8- and alpha beta TCR+NK1.1+ cells.

1990 • 196 citations

Emergence of NK1.1+ cells as effectors of IFN-gamma dependent immunity to Toxoplasma gondii in MHC class I-deficient mice.

1993 • 193 citations

Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles.

1994 • 193 citations

Ly-49 multigene family expressed by IL-2-activated NK cells.

1994 • 180 citations

Specificity of HLA class I antigen recognition by human NK clones: evidence for clonal heterogeneity, protection by self and non-self alleles, and influence of the target cell type.

1993 • 178 citations

Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal.

1994 • 168 citations

Rearrangement and expression of T cell antigen receptor and gamma genes during thymic development.

1986 • 167 citations

Ly-49 mediates EL4 lymphoma adhesion to isolated class I major histocompatibility complex molecules.

1994 • 162 citations

A natural killer cell receptor specific for a major histocompatibility complex class I molecule.

1994 • 157 citations

Molecular cloning of the NK1.1 antigen, a member of the NKR-P1 family of natural killer cell activation molecules.

1992 • 155 citations

T cell-specific gamma genes in C57BL/10 mice. Sequence and expression of new constant and variable region genes.

1986 • 154 citations

Stimulation of murine natural killer (NK) cells by a monoclonal antibody specific for the NK1.1 antigen. IL-2-activated NK cells possess additional specific stimulation pathways.

1991 • 148 citations

Chromosomal location of the Ly-49 (A1, YE1/48) multigene family. Genetic association with the NK 1.1 antigen.

1990 • 144 citations

A murine T lymphocyte antigen belongs to a supergene family of type II integral membrane proteins.

1989 • 139 citations

Demonstration by class I gene transfer that reduced susceptibility of human cells to natural killer cell‐mediated lysis is inversely correlated with HLA class I antigen expression

1989 • 133 citations

Ly-49 multigene family. New members of a superfamily of type II membrane proteins with lectin-like domains.

1991 • 132 citations

Tyrosine phosphorylation of the Fc gamma RIII(CD16): zeta complex in human natural killer cells. Induction by antibody-dependent cytotoxicity but not by natural killing.

1991 • 129 citations

Increase in NK cell number and turnover rate during acute viral infection.

1983 • 124 citations

NKR-P1, an activating molecule on rat natural killer cells, stimulates phosphoinositide turnover and a rise in intracellular calcium.

1991 • 124 citations

Recognition structures on natural killer cells

1993 • 123 citations

Mouse NKR-P1. A family of genes selectively coexpressed in adherent lymphokine-activated killer cells.

1991 • 121 citations

Host MHC class I molecules modulate in vivo expression of a NK cell receptor.

1994 • 119 citations

Thy-1+ dendritic epidermal cells belong to the T-cell lineage.

1987 • 111 citations

Increased resistance to non-MHC-restricted cytotoxicity related to HLA A, B expression. Direct demonstration using beta 2-microglobulin-transfected Daudi cells.

1988 • 106 citations

The involvement of oncogenes and tumor suppressor genes in the control of apoptosis

1992 • 99 citations

The alpha 1/alpha 2 domains of class I HLA molecules confer resistance to natural killing.

1989 • 95 citations

ROLE OF TARGET HISTOCOMPATIBILITY ANTIGENS IN REGULATION OF NATURAL KILLER ACTIVITY: A REEVALUATION AND A HYPOTHESIS11Based on a doctoral thesis at The Karolinska Institute, supported by grants from the Karolinska Institute, The Swedish Cancer Society, The National Cancer Institute (US DHEW) and The Engwall Foundation.

1985 • 76 citations

Gene rearrangement in cells with natural killer activity and expression of the β-chain of the T-cell antigen receptor

1985 • 72 citations

T cell receptor genes do not rearrange or express functional transcripts in natural killer cells of scid mice.

1987 • 59 citations

An expanded population of natural killer cells in mice with severe combined immunodeficiency (SCID) lack rearrangement and expression of T cell receptor genes.

1986 • 47 citations

Nucleotide sequence analysis of 95 kb near the 3′ end of the murine T-cell receptor αδ chain locus: Strategy and methodology

1992 • 46 citations

Evidence that the T cell antigen receptor may not be involved in cytotoxicity mediated by gamma/delta and alpha/beta thymic cell lines.

1987 • 43 citations

Delta-chains of dendritic epidermal T cell receptors are diverse but pair with gamma-chains in a restricted manner.

1989 • 42 citations

Expression of C gamma 4 T cell receptors and lack of isotype exclusion by dendritic epidermal T cell lines.

1988 • 28 citations

Expression and rearrangement of the alpha, beta, and gamma chain genes of the T cell receptor in cloned murine large granular lymphocyte lines. No correlation with the cytotoxic spectrum.

1986 • 27 citations

Natural killer cells: definition of a cell type rather than a function

1987 • 19 citations

Expression of the NK-TR gene is required for NK-like activity in human T cells.

1994 • 17 citations

The murine NK2.1 antigen: a 130 kD glycoprotein dimer expressed by a natural killer cell subset of the spleen, thymus and lymph nodes

1993 • 6 citations