Mutual regulation of conventional protein kinase C and a ubiquitin ligase complex

THE UBIQUITIN SYSTEM

1998 • 8,360 citations

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976

1993 • 1,589 citations

A ubiquitin ligase complex assembles linear polyubiquitin chains

2006 • 752 citations

THE PROTEIN KINASE C FAMILY: HETEROGENEITY AND ITS IMPLICATIONS

1989 • 739 citations

Proteolytic activation of calcium-activated, phospholipid-dependent protein kinase by calcium-dependent neutral protease.

1983 • 601 citations

Multiple pathways control protein kinase C phosphorylation

2000 • 598 citations

Activation of Protein Kinase C Triggers Its Ubiquitination and Degradation

1998 • 333 citations

Protein kinase C (PKC) family in cancer progression

2005 • 252 citations

Identification of the ubiquitin–protein ligase that recognizes oxidized IRP2

2003 • 177 citations

The von Hippel-Lindau Tumor Suppressor Protein Mediates Ubiquitination of Activated Atypical Protein Kinase C

2001 • 171 citations

Ubiquitination of Protein Kinase C-α and Degradation by the Proteasome

1996 • 161 citations

Mutagenesis of the pseudosubstrate site of protein kinase C leads to activation

1990 • 144 citations

Protein kinase C isoforms as therapeutic targets in nervous system disease states

2001 • 114 citations

Bryostatin 1 and phorbol ester down-modulate protein kinase C-alpha and -epsilon via the ubiquitin/proteasome pathway in human fibroblasts.

1997 • 108 citations

Caspase-1 and Caspase-8 Cleave and Inactivate Cellular Parkin

2003 • 78 citations

Dephosphorylation of activated protein kinase C contributes to downregulation by bryostatin

1996 • 74 citations

Caspase-mediated Parkin Cleavage in Apoptotic Cell Death

2002 • 64 citations

The Hepatitis B Virus X-associated Protein, XAP3, Is a Protein Kinase C-binding Protein

1997 • 62 citations

A potential proteasome-interacting motif within the ubiquitin-like domain of parkin and other proteins

2003 • 60 citations

Molecular Cloning and Characterization of a Novel Protein Kinase C-Interacting Protein with Structural Motifs Related to RBCC Family Proteins

1998 • 55 citations

Phosphorylation is required for PMA- and cell-cycle-induced degradation of protein kinase Cδ

2002 • 46 citations

Activation-dependent degradation of protein kinase Cη

2000 • 35 citations