A potential proteasome-interacting motif within the ubiquitin-like domain of parkin and other proteins

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1997 • 71,835 citations

CONFIDENCE LIMITS ON PHYLOGENIES: AN APPROACH USING THE BOOTSTRAP

1985 • 39,646 citations

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1985 • 18,213 citations

The Pfam protein families database.

2002 • 14,298 citations

T-coffee: a novel method for fast and accurate multiple sequence alignment 1 1Edited by J. Thornton

2000 • 6,765 citations

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

1998 • 5,063 citations

The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction

2002 • 4,069 citations

SMART, a simple modular architecture research tool: Identification of signaling domains

1998 • 3,523 citations

Plasma Homocysteine as a Risk Factor for Dementia and Alzheimer's Disease

2002 • 3,174 citations

Prediction of Protein Secondary Structure at Better than 70% Accuracy

1993 • 2,958 citations

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

2000 • 1,975 citations

Hidden Markov models

1996 • 1,313 citations

Multiple Associated Proteins Regulate Proteasome Structure and Function

2002 • 633 citations

A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14

2001 • 495 citations

The Ubiquitin-related BAG-1 Provides a Link between the Molecular Chaperones Hsc70/Hsp70 and the Proteasome

2000 • 478 citations

Deciphering protein sequence information through hydrophobic cluster analysis (HCA): current status and perspectives

1997 • 473 citations

Proteasome subunit Rpn1 binds ubiquitin-like protein domains

2002 • 457 citations

Rad23 links DNA repair to the ubiquitin/proteasome pathway

1998 • 452 citations

The UBA domain: a sequence motif present in multiple enzyme classes of the ubiquitination pathway

1996 • 397 citations

Emerging Roles of Ubiquitin in Transcription Regulation

2002 • 395 citations

Herp, a New Ubiquitin-like Membrane Protein Induced by Endoplasmic Reticulum Stress

2000 • 308 citations

Interaction of hHR23 with S5a

1999 • 261 citations

Covariation of mutations in the V3 loop of human immunodeficiency virus type 1 envelope protein: an information theoretic analysis.

1993 • 261 citations

How frequent are correlated changes in families of protein sequences?

1994 • 251 citations

Structural Studies of the Interaction between Ubiquitin Family Proteins and Proteasome Subunit S5a

2002 • 218 citations

MPN+, a putative catalytic motif found in a subset of MPN domain proteins from eukaryotes and prokaryotes, is critical for Rpn11 function.

2002 • 211 citations

Ubiquitylation of BAG-1 Suggests a Novel Regulatory Mechanism during the Sorting of Chaperone Substrates to the Proteasome

2002 • 189 citations

Transferring substrates to the 26S proteasome

2003 • 172 citations

Protein sequence motifs

1996 • 156 citations

Ubiquitin and the synapse

2002 • 151 citations

Ubiquitin-like proteins and Rpn10 play cooperative roles in ubiquitin-dependent proteolysis

2002 • 134 citations

Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein

2000 • 95 citations

New mutation (R42P) of the parkin gene in the ubiquitinlike domain associated with parkinsonism

2001 • 62 citations

rsc: a novel oncogene with structural and functional homology with the gene family of exchange factors for Ral

1997 • 60 citations

The UBA domain: a sequence motif present in multiple enzyme classes of the ubiquitination pathway

1996 • 49 citations

Sensitive protein comparisons with profiles and hidden Markov models

2000 • 45 citations