Identification of the ubiquitin–protein ligase that recognizes oxidized IRP2

THE UBIQUITIN SYSTEM

1998 • 8,360 citations

Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O ₂ -Regulated Prolyl Hydroxylation

2001 • 5,255 citations

HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O ₂ Sensing

2001 • 4,537 citations

Mechanisms Underlying Ubiquitination

2001 • 3,555 citations

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

2000 • 1,975 citations

Themes and variations on ubiquitylation

2001 • 1,475 citations

Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress.

1996 • 1,311 citations

Regulating the fate of mRNA: The control of cellular iron metabolism

1993 • 1,233 citations

RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

1999 • 1,134 citations

Ubiquitination of a New Form of α-Synuclein by Parkin from Human Brain: Implications for Parkinson's Disease

2001 • 1,036 citations

Degradation of oxidized proteins by the 20S proteasome

2001 • 846 citations

Does this have a familiar RING?

1996 • 632 citations

Ubiquitin dependence of selective protein degradation demonstrated in the mammalian cell cycle mutant ts85

1984 • 533 citations

Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice

2001 • 479 citations

E3 ubiquitin ligase that recognizes sugar chains

2002 • 344 citations

Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: Implications for degradation of oxidized proteins

1998 • 297 citations

Molecular characterization of a second iron-responsive element binding protein, iron regulatory protein 2. Structure, function, and post-translational regulation.

1994 • 221 citations

Requirements for iron-regulated degradation of the RNA binding protein, iron regulatory protein 2.

1995 • 209 citations

Hemin-mediated oxidative degradation of proteins.

1984 • 173 citations

Hypoxia Post-translationally Activates Iron-regulatory Protein 2

1999 • 147 citations

The Hepatitis B Virus X-associated Protein, XAP3, Is a Protein Kinase C-binding Protein

1997 • 62 citations

Molecular Cloning and Characterization of a Novel Protein Kinase C-Interacting Protein with Structural Motifs Related to RBCC Family Proteins

1998 • 55 citations

A family of structurally related RING finger proteins interacts specifically with the ubiquitin-conjugating enzyme UbcM4¹

1999 • 50 citations

Involvement of Heme in the Degradation of Iron-regulatory Protein 2

1998 • 48 citations