Regulatory DNA‐binding proteins in yeast: An overview

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

THE HEAT-SHOCK RESPONSE

1986 • 4,580 citations

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

1987 • 3,057 citations

Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes.

1985 • 2,450 citations

Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements

1987 • 2,107 citations

How eukaryotic transcriptional activators work

1988 • 1,924 citations

High-frequency transformation of yeast: autonomous replication of hybrid DNA molecules.

1979 • 1,504 citations

EUKARYOTIC TRANSCRIPTIONAL REGULATORY PROTEINS

1989 • 1,299 citations

Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region

1985 • 1,244 citations

In vivo sequence requirements of the SV40 early promoter region

1981 • 1,156 citations

The molecular biology of the yeast saccharomyces: Metabolism and gene expression

1983 • 1,118 citations

Nucleotide sequence from the neurogenic locus Notch implies a gene product that shares homology with proteins containing EGF-like repeats

1985 • 1,063 citations

Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element

1988 • 983 citations

Promoter Sequences of Eukaryotic Protein-Coding Genes

1980 • 971 citations

Sequences That Regulate the Divergent GAL1-GAL10 Promoter in Saccharomyces cerevisiae

1984 • 955 citations

Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of Yeast

1986 • 946 citations

Deletion analysis of GAL4 defines two transcriptional activating segments

1987 • 898 citations

Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation

1988 • 886 citations

O-glycosylation of eukaryotic transcription factors: Implications for mechanisms of transcriptional regulation

1988 • 884 citations

Yeast plasma membrane ATPase is essential for growth and has homology with (Na+ + K+), K+- and Ca2+-ATPases

1986 • 801 citations

Specific interaction of a purified transcription factor with an internal control region of 5S RNA genes

1980 • 772 citations

Specific DNA binding of GAL4, a positive regulatory protein of yeast

1985 • 767 citations

An RNA polymerase II transcription factor binds to an upstream element in the adenovirus major late promoter

1985 • 763 citations

Activation of transcription by two factors that bind promoter and enhancer sequences of the human metallothionein gene and SV40

1987 • 762 citations

Human CCAAT-binding proteins have heterologous subunits

1988 • 712 citations

Sequence of a Drosophila segmentation gene: protein structure homology with DNA-binding proteins

1984 • 686 citations

A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor

1985 • 686 citations

A model fungal gene regulatory mechanism: the GAL genes of Saccharomyces cerevisiae

1987 • 676 citations

Negative effect of the transcriptional activator GAL4

1988 • 672 citations

Heme regulates transcription of the CYC1 gene of S. cerevisiae via an upstream activation site

1983 • 667 citations

Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements

1987 • 637 citations

Separation of DNA Binding from the Transcription-Activating Function of a Eukaryotic Regulatory Protein

1986 • 626 citations

Nucleotide sequence of an RNA polymerase binding site at an early T7 promoter.

1975 • 597 citations

A GAL10-CYC1 hybrid yeast promoter identifies the GAL4 regulatory region as an upstream site.

1982 • 575 citations

Life cycle of the budding yeast Saccharomyces cerevisiae

1988 • 565 citations

The primary structure of the Saccharomyces cerevisiae gene for alcohol dehydrogenase.

1982 • 558 citations

A drosophila RNA polymerase II transcription factor binds to the regulatory site of an hsp 70 gene

1984 • 534 citations

GAL4 activates transcription in Drosophila

1988 • 521 citations

Two DNA-binding factors recognize specific sequences at silencers, upstream activating sequences, autonomously replicating sequences, and telomeres in Saccharomyces cerevisiae.

1988 • 511 citations

Sequence of a yeast DNA fragment containing a chromosomal replicator and the TRP1 gene

1980 • 511 citations

Distinctly regulated tandem upstream activation sites mediate catabolite repression of the CYC1 gene of S. cerevisiae

1984 • 501 citations

Eukaryotic RNA Polymerase

1985 • 500 citations

GCN4 protein, synthesize in vitro, binds HIS3 regulatory sequences: Implications for general control of amino acid biosynthetic genes in yeast

1985 • 496 citations

Promoters, activator proteins, and the mechanism of transcriptional initiation in yeast

1987 • 476 citations

Evidence for translational regulation of the activator of general amino acid control in yeast.

1984 • 472 citations

Identification of regulatory sequences in the prelude sequences of an H2A histone gene by the study of specific deletion mutants in vivo.

1980 • 471 citations

Sequences that regulate the divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae.

1984 • 462 citations

Germline Transformation Used to Define Key Features of Heat-Shock Response Elements

1988 • 451 citations

Five SWI genes are required for expression of the HO gene in yeast

1984 • 450 citations

Avian sarcoma virus 17 carries the jun oncogene.

1987 • 445 citations

MUTANTS OF S. CEREVISIAE DEFECTIVE IN THE MAINTENANCE OF MINICHROMOSOMES

1984 • 419 citations

Isolation of the gene encoding the S. cerevisiae heat shock transcription factor

1988 • 417 citations

Regulation and function of the Drosophila segmentation gene fushi tarazu

1987 • 415 citations

Mutually exclusive interaction of the CCAAT-binding factor and of a displacement protein with overlapping sequences of a histone gene promoter

1987 • 407 citations

Nucleotide sequence comparisons and functional analysis of yeast centromere DNAs

1982 • 399 citations

Saccharomyces cerevisiae GAL1-GAL10 Divergent Promoter Region: Location and Function of the Upstream Activating Sequence UAS_G

1984 • 395 citations

GCN4, a eukaryotic transcriptional activator protein, binds as a dimer to target DNA.

1987 • 395 citations

Cell cycle control of the yeast HO gene: Cis- and Trans-acting regulators

1987 • 392 citations

A repressor (MATα2 product) and its operator control expression of a set of cell type specific genes in yeast

1985 • 368 citations

Eukaryotic DNA segments capable of autonomous replication in yeast.

1980 • 366 citations

Similarity between cell-cycle genes of budding yeast and fission yeast and the Notch gene of Drosophila

1987 • 366 citations

Function of a yeast TATA element-binding protein in a mammalian transcription system

1988 • 364 citations

MUTATIONS AFFECTING TY-MEDIATED EXPRESSION OF THE HIS4 GENE OF SACCHAROMYCES CEREVISIAE

1984 • 355 citations

Factors involved in specific transcription in mammalian RNA polymerase II. Functional analysis of initiation factors IIA and IID and identification of a new factor operating at sequences downstream of the initiation site.

1987 • 355 citations

Saturation Mutagenesis of the Yeast his3 Regulatory Site: Requirements for Transcriptional Induction and for Binding by GCN4 Activator Protein

1986 • 352 citations

The carboxy-terminal 30 amino acids of GAL4 are recognized by GAL80

1987 • 349 citations

Purification and characterization of a heat-shock element binding protein from yeast.

1987 • 348 citations

The yeast cell-type-specific repressor α2 acts cooperatively with a non-cell-type-specific protein

1988 • 348 citations

Compilation and analysis of eukaryotic POL II promoter sequences

1986 • 345 citations

Fly and frog homoeo domains show homologies with yeast mating type regulatory proteins

1984 • 341 citations

A synthetic heat-shock promoter element confers heat-inducibility on the herpes simplex virus thymidine kinase gene.

1982 • 333 citations

A yeast silencer contains sequences that can promote autonomous plasmid replication and transcriptional activation

1987 • 332 citations

Yeast YAP1 encodes a novel form of the jun family of transcriptional activator proteins.

1989 • 328 citations

Structural and functional characterization of the short acidic transcriptional activation region of yeast GCN4 protein

1988 • 325 citations

Transcription in yeast activated by a putative amphipathic α helix linked to a DNA binding unit

1987 • 324 citations

Saccharomyces cerevisiae protein involved in plasmid maintenance is necessary for mating of MATα cells

1988 • 323 citations

Yeast HAP1 activator binds to two upstream activation sites of different sequence

1987 • 317 citations

Separation and characterization of factors mediating accurate transcription by RNA polymerase II.

1982 • 314 citations

Use of lacZ fusions to delimit regulatory elements of the inducible divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae.

1984 • 310 citations

Functional dissection and sequence of yeast HAP1 activator

1989 • 309 citations

Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box

1989 • 303 citations

Compilation of transcription regulating proteins

1988 • 303 citations

The sequence of the DNAs coding for the mating-type loci of saccharomyces cerevisiae

1981 • 286 citations

Amino terminus of the yeast GAL4 gene product is sufficient for nuclear localization.

1984 • 284 citations

Connections Between Transcriptional Activators, Silencers, and Telomeres as Revealed by Functional Analysis of a Yeast DNA-Binding Protein

1988 • 284 citations

Isolation of the yeast regulatory gene GAL4 and analysis of its dosage effects on the galactose/melibiose regulon.

1982 • 280 citations

Regulation of yeast mating-type interconversion: feedback control of HO gene expression by the mating-type locus.

1983 • 280 citations

Positive regulation in the general amino acid control of Saccharomyces cerevisiae.

1983 • 279 citations

Homology between the DNA-binding domain of the GCN4 regulatory protein of yeast and the carboxyl-terminal region of a protein coded for by the oncogene jun.

1987 • 279 citations

Factors involved in specific transcription by mammalian RNA polymerase II. Purification and functional analysis of initiation factors IIB and IIE.

1987 • 278 citations

Multiple forms of the human gene-specific transcription factor USF. I. Complete purification and identification of USF from HeLa cell nuclei.

1988 • 276 citations

Primary Structure of the Saccharomyces cerevisiae GAL4 Gene

1984 • 276 citations

Regulation of Pyrimidine Biosynthesis in Saccharomyces cerevisiae

1968 • 272 citations

A yeast and a human CCAAT-binding protein have heterologous subunits that are functionally interchangeable

1988 • 263 citations

The DNA-binding domains of the jun oncoprotein and the yeast GCN4 transcriptional activator protein are functionally homologous

1987 • 260 citations

Control of cell type in yeast by the mating type locus

1981 • 259 citations

Activation of the yeast HO gene by release from multiple negative controls

1987 • 257 citations

5' untranslated sequences are required for the translational control of a yeast regulatory gene.

1984 • 257 citations

Isolation of the gene encoding the yeast TATA binding protein TFIID: A gene identical to the SPT15 suppressor of Ty element insertions

1989 • 256 citations

A comparison of yeast ribosomal protein gene DNA sequences

1984 • 256 citations

Yeast HAP2 and HAP3 activators both bind to the CYC1 upstream activation site, UAS2, in an interdependent manner

1987 • 255 citations

A yeast activity can substitute for the HeLa cell TATA box factor

1988 • 253 citations

Chromosomal ARS and CEN elements bind specifically to the yeast nuclear scaffold

1988 • 251 citations

Functional selection and analysis of yeast centromeric DNA

1985 • 249 citations

Multiple Global Regulators Control HIS4 transcription in Yeast

1987 • 246 citations

Specific protein binding to far upstream activating sequences in polymerase II promoters.

1985 • 246 citations

Yeast HAP1 activator competes with the factor RC2 for binding to the upstream activation site UAS1 of the CYC1 gene

1987 • 245 citations

Mutations Affecting the Repressibility of Arginine Biosynthetic Enzymes in Sacchromyces cerevisiae

1970 • 245 citations

A hierarchy of trans-acting factors modulates translation of an activator of amino acid biosynthetic genes in Saccharomyces cerevisiae.

1985 • 244 citations

SPT15, the gene encoding the yeast TATA binding factor TFIID, is required for normal transcription initiation in vivo

1989 • 239 citations

A protein involved in minichromosome maintenance in yeast binds a transcriptional enhancer conserved in eukaryotes.

1989 • 239 citations

Identification of silencer binding proteins from yeast: possible roles in SIR control and DNA replication

1987 • 238 citations

Mating signals control expression of mutations resulting from insertion of a transposable repetitive element adjacent to diverse yeast genes

1980 • 237 citations

Transcriptional activation by the SV40 AP-1 recognition element in yeast is mediated by a factor similar to AP-1 that is distinct from GCN4

1988 • 237 citations

Saturation mutagenesis of a yeast his3 "TATA element": genetic evidence for a specific TATA-binding protein.

1988 • 236 citations

Unusual DNA sequences associated with the ends of yeast chromosomes

1984 • 236 citations

MATα1 protein, a yeast transcription activator, binds synergistically with a second protein to a set of cell-type-specific genes

1987 • 236 citations

Purification of a yeast protein that binds to origins of DNA replication and a transcriptional silencer.

1988 • 234 citations

Cloning, sequencing and transcriptional control of the Schizosaccharomyces pombe cdc10 ‘start’ gene.

1985 • 228 citations

Cooperative DNA binding of the yeast transcriptional activator GAL4.

1988 • 227 citations

Interaction of positive and negative regulatory proteins in the galactose regulon of yeast

1987 • 226 citations

Genetics of alcohol dehydrogenase in Saccharomyces cerevisiae

1975 • 225 citations

REGULATION OF GENES CONTROLLING SYNTHESIS OF THE GALACTOSE PATHWAY ENZYMES IN YEAST

1966 • 224 citations

Molecular mechanisms of transcriptional regulation in yeast

1990 • 224 citations

A general upstream binding factor for genes of the yeast translational apparatus.

1985 • 222 citations

Constitutive binding of yeast heat shock factor to DNA in vivo.

1988 • 221 citations

MOLECULAR GENETICS OF YEAST MATING TYPE

1982 • 219 citations

a1 Protein alters the dna binding specificity of α2 repressor

1988 • 218 citations

Sequence homology of the yeast regulatory protein ADR1 with Xenopus transcription factor TFIIIA

1986 • 217 citations

Bent DNA at a yeast autonomously replicating sequence

1986 • 217 citations

The saccharomyces and Drosophila heat shock transcription factors are identical in size and DNA binding properties

1987 • 214 citations

The SPT3 gene is required for normal transcription of Ty elements in S. cerevisiae

1984 • 212 citations

Recognition sequences of repressor and polymerase in the operators of bacteriophage lambda

1975 • 211 citations

Deletion mutations affecting autonomously replicating sequence ARS1 of Saccharomyces cerevisiae.

1984 • 210 citations

Nucleotide sequence of an RNA polymerase binding site from the DNA of bacteriophage fd.

1975 • 209 citations

Saccharomyces cerevisiae GAL1-GAL10 divergent promoter region: location and function of the upstream activating sequence UASG.

1984 • 209 citations

The yeast SWI4 protein contains a motif present in developmental regulators and is part of a complex involved in cell-cycle-dependent transcription

1989 • 207 citations

A yeast operator overlaps an upstream activation site

1987 • 200 citations

The Origins of Gene Instability in Yeast

1980 • 198 citations

Transcriptional Regulation in the Yeast Life Cycle

1987 • 196 citations

Specific interaction between a transcription factor and the upstream element of the adenovirus-2 major late promoter.

1985 • 195 citations

Identification and comparison of two sequence elements that confer cell-type specific transcription in yeast

1985 • 192 citations

Yeast TATA-box transcription factor gene.

1989 • 191 citations

Cell Interactions and Regulation of Cell Type in the Yeast Saccharomyces Cerevisiae

1983 • 189 citations

Genetics of alcohol dehydrogenase inSaccharomyces cerevisiac

1975 • 189 citations

Regulation of mating-type information in yeast

1984 • 187 citations

UASs and enhancers: Common mechanism of transcriptional activation in yeast and mammals

1988 • 187 citations

GLYCOLYSIS MUTANTS IN SACCHAROMYCES CEREVISIAE

1978 • 186 citations

Plasmids carrying the yeast OMP decarboxylase structural and regulatory genes: Transcription regulation in a foreign environment

1983 • 184 citations

RPC40, a unique gene for a subunit shared between yeast RNA polymerases A and C

1987 • 184 citations

Similarity Between the Transcriptional Silencer Binding Proteins ABF1 and RAP1

1989 • 180 citations

The JUN oncoprotein, a vertebrate transcription factor, activates transcription in yeast

1988 • 180 citations

Isolation and preliminary characterization of the GAL4 gene, a positive regulator of transcription in yeast.

1982 • 176 citations

A positive regulatory gene is required for accumulation of the functional messenger RNA for the glucose-repressible alcohol dehydrogenase from Saccharomyces cerevisiae

1981 • 176 citations

Multiple forms of the human gene-specific transcription factor USF. II. DNA binding properties and transcriptional activity of the purified HeLa USF.

1988 • 175 citations

Roles of two DNA-binding factors in replication, segregation and transcriptional repression mediated by a yeast silencer.

1988 • 174 citations

REGULATORY PROTEINS IN YEAST

1987 • 173 citations

Identification of a DNA binding factor involved in cell-cycle control of the yeast HO gene

1989 • 171 citations

Both positive and negative regulators of HO transcription are required for mother-cell-specific mating-type switching in yeast

1987 • 171 citations

Genetic evidence that zinc is an essential co-factor in the DNA binding domain of GAL4 protein

1987 • 169 citations

Yeast activators stimulate plant gene expression

1988 • 167 citations

A GAL family of upstream activating sequences in yeast: roles in both induction and repression of transcription.

1986 • 162 citations

Interaction of GAL4 and GAL80 gene regulatory proteins in vitro.

1987 • 161 citations

Factors involved in specific transcription by mammalian RNA polymerase II. Transcription factor IIS stimulates elongation of RNA chains.

1987 • 160 citations

The yeast transcription activator PRTF, a homolog of the mammalian serum response factor, is encoded by the MCM1 gene.

1989 • 160 citations

Analysis of theKluyveromyces lactispositive regulatory geneLAC9reveals functional homology to, but sequence divergence from, theSaccharomyces cerevisiae GALAgene

1986 • 158 citations

Isolation of a Saccharomyces cerevisiae centromere DNA-binding protein, its human homolog, and its possible role as a transcription factor.

1987 • 158 citations

Connections between transcriptional activators, silencers, and telomeres as revealed by functional analysis of a yeast DNA-binding protein.

1988 • 157 citations

Solubilization by lysolecithin and purification of the plasma membrane ATPase of the yeast Schizosaccharomyces pombe.

1978 • 157 citations

Cloning of the gene encoding the yeast protein BTF1Y, which can substitute for the human TATA box-binding factor.

1989 • 154 citations

Flexibility of the yeast alpha 2 repressor enables it to occupy the ends of its operator, leaving the center free.

1988 • 150 citations

Structure of the Saccharomyces cerevisiae HO gene and analysis of its upstream regulatory region.

1986 • 148 citations

The yeast H+-ATPase gene is controlled by the promoter binding factor TUF

1989 • 148 citations

Characterization of a transcription factor involved in mother cell specific transcription of the yeast HO gene.

1988 • 147 citations

Isolation and characterization of further Cis- and Trans-acting regulatory elements involved in the synthesis of glucose-repressible alcohol dehydrogenase (ADHII) in Saccharomyces cerevisiae

1979 • 147 citations

Yeast HAP2 and HAP3: Transcriptional Activators in a Heteromeric Complex

1988 • 145 citations

Sequence and nuclear localization of the Saccharomyces cerevisiae HAP2 protein, a transcriptional activator.

1987 • 143 citations

Primary structure of the Saccharomyces cerevisiae GAL4 gene.

1984 • 142 citations

Yeast regulatory gene PPR1

1984 • 141 citations

Identification of sites required for repression of a silent mating type locus in yeast

1984 • 141 citations

Accurate initiation at RNA polymerase II promoters in extracts from Saccharomyces cerevisiae.

1987 • 141 citations

Cloning and molecular analysis of the HAP2 locus: a global regulator of respiratory genes in Saccharomyces cerevisiae.

1985 • 140 citations

A MUTATION THAT PERMITS THE EXPRESSION OF NORMALLY SILENT COPIES OF MATING-TYPE INFORMATION IN SACCHAROMYCES CEREVISIAE

1979 • 138 citations

Expression of the SV40 promoter in fission yeast: Identification and characterization of an AP-1-like factor

1988 • 138 citations

Tripartite Upstream Promoter Element Essential for Expression of Saccharomyces cerevisiae Ribosomal Protein Genes

1986 • 136 citations

Specific binding of TUF factor to upstream activation sites of yeast ribosomal protein genes.

1987 • 135 citations

Conserved sequences upstream of yeast ribosomal protein genes

1985 • 135 citations

The sequence of theSaccharomyces cerevisiaegenePH02codes for a regulatory protein with unusual aminoacid composition

1987 • 134 citations

A repetitive DNA sequence that confers cell-cycle START (CDC28)-dependent transcription of the HO gene in yeast

1985 • 134 citations

Mutational analysis of upstream activation sequence 2 of the CYC1 gene of Saccharomyces cerevisiae: a HAP2-HAP3-responsive site.

1988 • 133 citations

Control of Cell Type in Saccharomyces cerevisiae: Mating Type and Mating-type Interconversion

1981 • 132 citations

The gcr (glycolysis regulation) mutation of Saccharomyces cerevisiae.

1981 • 132 citations

Replacement of the promoter of the yeast plasma membrane ATPase gene by a galactose-dependent promoter and its physiological consequences

1987 • 131 citations

Regulation of expression of the galactose gene cluster in Saccharomyces cerevisiae

1983 • 131 citations

TUF, the yeast DNA-binding factor specific for UASrpg upstream activating sequences: identification of the protein and its DNA-binding domain.

1987 • 129 citations

Characterization of a Positive Regulatory Gene, LAC9, That Controls Induction of the Lactose-Galactose Regulon of Kluyveromyces lactis: Structural and Functional Relationships to GAL4 of Saccharomyces cerevisiae

1987 • 128 citations

Two zinc fingers of a yeast regulatory protein shown by genetic evidence to be essential for its function

1987 • 128 citations

RPA190, the gene coding for the largest subunit of yeast RNA polymerase A.

1988 • 124 citations

Purification of a factor specific for the upstream element of the adenovirus-2 major late promoter.

1986 • 123 citations

Homeo Domain of the Yeast Repressor α2 Is a Sequence-Specific DNA-Binding Domain But Is Not Sufficient for Repression

1987 • 121 citations

The HAP3 regulatory locus of Saccharomyces cerevisiae encodes divergent overlapping transcripts.

1988 • 119 citations

The human c-fos serum response factor and the yeast factors GRM/PRTF have related DNA-binding specificities.

1988 • 117 citations

Photofootprinting in vivo detects transcription-dependent changes in yeast TATA boxes

1987 • 117 citations

Activation of yeast RNA polymerase II transcription by a thymidine-rich upstream element in vitro.

1989 • 116 citations

At least 1400 base pairs of 5′-flanking DNA is required for the correct expression of the HO gene in yeast

1985 • 116 citations

Regulation of the galactose pathway in Saccharomyces cerevisiae : Induction of uridyl transferase mRNA and dependency on GAL4 gene function

1978 • 114 citations

Isolation and characterization of the positive regulatory gene ADR1 from Saccharomyces cerevisiae.

1983 • 114 citations

Yeast DNA replication in vitro: Initiation and elongation events mimic in vivo processes

1982 • 113 citations

In vivo DNA-binding properties of a yeast transcription activator protein.

1987 • 112 citations

Electron microscopic study of Saccharomyces cerevisiae rDNA chromatin replication.

1986 • 111 citations

Centromeric DNA from chromosome VI in Saccharomyces cerevisiae strains.

1982 • 111 citations

Conserved sequence elements upstream of the gene encoding yeast ribosomal protein L25 are involved in transcription activation.

1986 • 110 citations

The ABF1 factor is the transcriptional activator of the L2 ribosomal protein genes in Saccharomyces cerevisiae.

1990 • 110 citations

Cloning, nucleotide sequence, and expression of one of two genes coding for yeast elongation factor 1 alpha.

1985 • 109 citations

The gene encoding ARS-binding factor I is essential for the viability of yeast.

1989 • 105 citations

Mutations that inactivate a yeast transcriptional regulatory protein cluster in an evolutionarily conserved DNA binding domain.

1987 • 105 citations

Mutational and in vitro protein-binding studies on centromere DNA from Saccharomyces cerevisiae.

1987 • 104 citations

Identification of two factors which bind to the upstream sequences of a number of nuclear genes coding for mitochondrial proteins and to genetic elements important for cell division in yeast

1988 • 103 citations

Identification of AAS genes and their regulatory role in general control of amino acid biosynthesis in yeast.

1983 • 101 citations

Replication and Segregation of Plasmids Containing cis-Acting Regulatory Sites of Silent Mating-Type Genes in Saccharomyces cerevisiae Are Controlled by the SIR Genes

1987 • 100 citations

Role of conserved sequence elements in yeast centromere DNA.

1985 • 100 citations

Nucleotide sequence of the ARGRII regulatory gene and amino acid sequence homologies between ARGRII PPRI and GAL4 regulatory proteins

1986 • 100 citations

Functional domains of the yeast regulatory protein GAL4.

1986 • 95 citations

Identification of a DNA segment that is necessary and sufficient for alpha-specific gene control in Saccharomyces cerevisiae: implications for regulation of alpha-specific and a-specific genes.

1988 • 95 citations

Purification and characterization of proteins that bind to yeast ARSs.

1988 • 94 citations

Sequence, expression and mutational analysis of BAF1, a transcriptional activator and ARS1-binding protein of the yeast Saccharomyces cerevisiae.

1989 • 93 citations

Negative regulation of STE6 gene expression by the alpha 2 product of Saccharomyces cerevisiae.

1984 • 93 citations

Alterations in the adenine-plus-thymine-rich region of CEN3 affect centromere function in Saccharomyces cerevisiae.

1987 • 92 citations

DNA sequences of two yeast promoter-up mutants

1983 • 92 citations

The GCR1 Gene Encodes a Positive Transcriptional Regulator of the Enolase and Glyceraldehyde-3-Phosphate Dehydrogenase Gene Families in Saccharomyces cerevisiae

1987 • 92 citations

The yeast ribosomal protein L32 and its gene.

1987 • 92 citations

ADR1-mediated regulation of ADH2 requires an inverted repeat sequence.

1986 • 90 citations

Participation of transcriptional and post-transcriptional regulatory mechanisms in the control of arginine metabolism in yeast

1983 • 90 citations

A segment of GCN4 mRNA containing the upstream AUG codons confers translational control upon a heterologous yeast transcript.

1987 • 89 citations

Nucleotide sequence of the Saccharomyces cerevisiae arginase gene (CAR1) and its transcription under various physiological conditions

1984 • 87 citations

Identification of proteins involved in the regulation of yeast iso- 1-cytochrome C expression by oxygen.

1985 • 86 citations

Uninducible Mutants in the gal i Locus of Saccharomyces cerevisiae

1972 • 83 citations

The yeast regulatory protein ADR1 binds in a zinc-dependent manner to the upstream activating sequence of ADH2.

1988 • 81 citations

Constitutive transcription of yeast ribosomal protein gene TCM1 is promoted by uncommon cis- and trans-acting elements.

1988 • 77 citations

Cloning of yeast glycolysis genes by complementation

1982 • 75 citations

An ARS/silencer binding factor also activates two ribosomal protein genes in yeast

1989 • 74 citations

Cloning of a eukaryotic regulatory gene

1981 • 73 citations

The relationship of regulatory proteins and DNase I hypersensitive sites in the yeastGAL1-10genes

1985 • 73 citations

Specific interaction between a Saccharomyces cerevisiae protein and a DNA element associated with certain autonomously replicating sequences.

1988 • 73 citations

Yeast 2-micrometer plasmid DNA replication in vitro: origin and direction.

1981 • 72 citations

Isolation and DNA-binding characteristics of a protein involved in transcription activation of two divergently transcribed, essential yeast genes.

1989 • 72 citations

Isolation, physical characterization and expression analysis of theSaccharomyces cerevisiaepositive regulatory genePH04

1986 • 70 citations

Characterization of a positive regulatory gene, LAC9, that controls induction of the lactose-galactose regulon of Kluyveromyces lactis: structural and functional relationships to GAL4 of Saccharomyces cerevisiae.

1987 • 70 citations

A NEW GENE AFFECTING THE EFFICIENCY OF MATING-TYPE INTERCONVERSIONS IN HOMOTHALLIC STRAINS OF SACCHAROMYCES CEREVISIAE

1977 • 69 citations

Organization of the regulatory region of the yeast CYC7 gene: multiple factors are involved in regulation.

1987 • 67 citations

The determination of mother cell-specific mating type of switching in yeast by a specific regulator of HO transcription

1987 • 66 citations

Nucleotide sequence of the yeast regulatory geneGAL80

1984 • 66 citations

Deletion Analysis Identifies a Region, Upstream of the ADH2 Gene of Saccharomyces cerevisiae, Which Is Required for ADR1-Mediated Derepression

1985 • 66 citations

Effects of Ty Insertions on HIS4 Transcription in Saccharomyces cerevisiae

1984 • 65 citations

The effects of ADR1 and CCR1 gene dosage on the regulation of the glucose-repressible alcohol dehydrogenase from Saccharomyces cerevisiae

1987 • 64 citations

Adjacent upstream activation sequence elements synergistically regulate transcription of ADH2 in Saccharomyces cerevisiae.

1989 • 63 citations

Tripartite upstream promoter element essential for expression of Saccharomyces cerevisiae ribosomal protein genes.

1986 • 63 citations

Interactions of purified transcription factors: binding of yeast MAT alpha 1 and PRTF to cell type-specific, upstream activating sequences.

1988 • 62 citations

Repression of transcription in yeast

1985 • 59 citations

Homoeo-domain homology in yeast MATα2 is essential for repressor activity

1986 • 57 citations

Replication and segregation of plasmids containing cis-acting regulatory sites of silent mating-type genes in Saccharomyces cerevisiae are controlled by the SIR genes.

1987 • 54 citations

The overproducing CYP1 and the underproducing hap1 mutations are alleles of the same gene which regulates in trans the expression of the structural genes encoding iso-cytochromes c

1986 • 53 citations

Yeast promoters URA1 and URA3

1985 • 52 citations

The OBF1 protein and its DNA-binding site are important for the function of an autonomously replicating sequence in Saccharomyces cerevisiae.

1989 • 52 citations

Regulation of arginine metabolism in Saccharomyces cerevisiae: expression of the three ARGR regulatory genes and cellular localization of their products

1987 • 52 citations

Réseau d'interactions entre des gènes non liés: régulation synergique ou antagoniste de la synthèse de l'iso-l-cytochrome c, de l'iso-2-cytochrome c et du cytochrome b2

1976 • 50 citations

General amino acid control and specific arginine repression in Saccharomyces cerevisiae: physical study of the bifunctional regulatory region of the ARG3 gene.

1985 • 48 citations

Identification of functional regions in the yeast transcriptional activator ADR1.

1988 • 48 citations

Constitutive RNA synthesis for the yeast activator ADR1 and identification of the ADR1-5c mutation: implications in posttranslational control of ADR1.

1986 • 47 citations

Isolation of three new avian sarcoma viruses: ASV 9, ASV 17, and ASV 25

1985 • 47 citations

Regulation of expression and activity of the yeast transcription factor ADR1.

1988 • 46 citations

Transcription of the ADH2 gene in Saccharomyces cerevisiae is limited by positive factors that bind competitively to its intact promoter region on multicopy plasmids.

1987 • 46 citations

Structure and Expression of Ribosomal Protein Genes in Yeast

1986 • 45 citations

A highly conserved sequence in yeast heat shock gene promoters

1988 • 44 citations

A single Saccharomyces cerevisiae upstream activation site (UAS1) has two distinct regions essential for its activity.

1986 • 39 citations

Studies on the structure, expression and function of the yeast regulatory gene PH02

1988 • 38 citations

The GCR1 gene encodes a positive transcriptional regulator of the enolase and glyceraldehyde-3-phosphate dehydrogenase gene families in Saccharomyces cerevisiae.

1987 • 38 citations

Transcription of multiple copies of the yeast GAL7 gene is limited by specific factors in addition to GAL4

1987 • 38 citations

Isolation and characterization of the yeast ARGRII gene involved in regulating both anabolism and catabolism of arginine

1985 • 37 citations

Regulation of the expression of iso 2-cytochrome c gene in S. cerevisiae: cloning of the positive regulatory gene CYP1 and identification of the region of its target sequence on the structural gene CYP3

1985 • 37 citations

Deletion analysis identifies a region, upstream of the ADH2 gene of Saccharomyces cerevisiae, which is required for ADR1-mediated derepression.

1985 • 36 citations

The General Control Activator Protein GCN4 Is Essential for a Basal Level of ARO3 Gene Expression in Saccharomyces cerevisiae

1989 • 36 citations

Effects of Ty insertions on HIS4 transcription in Saccharomyces cerevisiae.

1984 • 36 citations

Transposable element-mediated enhancement of gene expression in Saccharomyces cerevisiae involves sequence-specific binding of a trans-acting factor.

1988 • 34 citations

In vitro association of a replication complex with a yeast chromosomal replicator.

1983 • 33 citations

Genetic and molecular characterization of suppressors of SIR4 mutations in Saccharomyces cerevisiae.

1989 • 33 citations

Purification and characterization of OBF1: a Saccharomyces cerevisiae protein that binds to autonomously replicating sequences.

1989 • 32 citations

Yeast regulatory gene PPR1

1984 • 31 citations

The general control activator protein GCN4 is essential for a basal level of ARO3 gene expression in Saccharomyces cerevisiae.

1989 • 27 citations

Purification of isocitrate lyase from Saccharomyces cerevisiae

1988 • 16 citations

Existence de gènes régulateurs couplant la répression de la biosynthèse et l'induction du catabolisme de l'arginine dans Saccharomyces cerevisiae

1969 • 9 citations