The yeast RNA1 gene product necessary for RNA processing is located in the cytosol and apparently excluded from the nucleus.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

THE HEAT-SHOCK RESPONSE

1986 • 4,580 citations

Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor

1988 • 1,200 citations

Sterile host yeasts (SHY): A eukaryotic system of biological containment for recombinant DNA experiments

1979 • 967 citations

Splicing of Messenger RNA Precursors

1987 • 919 citations

Splicing of Messenger RNA Precursors

1984 • 874 citations

Structural rearrangements of tubulin and actin during the cell cycle of the yeast Saccharomyces.

1984 • 827 citations

Macromolecule Synthesis in Temperature-sensitive Mutants of Yeast

1967 • 728 citations

Protein Import into the Cell Nucleus

1986 • 544 citations

Targeting of E. coli β-galactosidase to the nucleus in yeast

1984 • 386 citations

The organization and transcription of the galactose gene cluster of Saccharomyces

1981 • 350 citations

Transfer RNA Modification

2005 • 350 citations

Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiae.

1989 • 340 citations

Transcription and processing of intervening sequences in yeast tRNA genes

1978 • 332 citations

Synthesis of ribosomes in Saccharomyces cerevisiae

1989 • 331 citations

TRANSFER RNA MODIFICATION

1987 • 310 citations

Amino terminus of the yeast GAL4 gene product is sufficient for nuclear localization.

1984 • 284 citations

[91] Immunoaffinity chromatography of proteins

1974 • 255 citations

A yeast mutant which accumulates precursor tRNAs

1978 • 231 citations

Splicing of Messenger RNA Precursors

1987 • 219 citations

The effect of temperature-sensitive RNA mutants on the transcription products from cloned ribosomal protein genes of yeast

1981 • 206 citations

Temperature-sensitive Yeast Mutant Defective in Ribonucleic Acid Production

1969 • 201 citations

Amino acid sequences that determine the nuclear localization of yeast histone 2B.

1987 • 194 citations

Saccharomyces cerevisiae tRNA ligase. Purification of the protein and isolation of the structural gene.

1986 • 185 citations

Identification of a yeast snRNP protein and detection of snRNP-snRNP interactions

1987 • 180 citations

Nuclear pre‐mRNA splicing in yeast

1989 • 156 citations

Macromolecule Synthesis and Breakdown in Relation to Sporulation and Meiosis in Yeast

1974 • 154 citations

The genes for fifteen ribosomal proteins of Saccharomyces cerevisiae.

1981 • 150 citations

Processing of intervening sequences: a new yeast mutant which fails to excise intervening sequences from precursor tRNAs

1980 • 147 citations

Splicing of yeast nuclear pre-mRNA in vitro requires a functional 40S spliceosome and several extrinsic factors.

1987 • 137 citations

PRP4: a protein of the yeast U4/U6 small nuclear ribonucleoprotein particle.

1989 • 131 citations

Open reading frame expression vectors: a general method for antigen production in Escherichia coli using protein fusions to beta-galactosidase.

1983 • 108 citations

Cytoplasmic anchoring proteins and the control of nuclear localization

1989 • 106 citations

Cloning and Characterization of LOS1, a Saccharomyces cerevisiae Gene That Affects tRNA Splicing

1987 • 104 citations

Intracellular targeting and import of an F1-ATPase beta-subunit-beta-galactosidase hybrid protein into yeast mitochondria.

1984 • 102 citations

RNA11 protein is associated with the yeast spliceosome and is localized in the periphery of the cell nucleus.

1988 • 102 citations

PRP4 (RNA4) from Saccharomyces cerevisiae: Its Gene Product Is Associated with the U4/U6 Small Nuclear Ribonucleoprotein Particle

1989 • 98 citations

A trans-acting suppressor restores splicing of a yeast intron with a branch point mutation.

1987 • 95 citations

Amino Acid Sequences That Determine the Nuclear Localization of Yeast Histone 2B

1987 • 86 citations

The Role of Cytoplasmic Membranes in Controlling the Transport of Nuclear Messenger RNA and Initiation of Protein Synthesis

1974 • 86 citations

Regulated overproduction of the GAL4 gene product greatly increases expression from galactose-inducible promoters on multi-copy expression vectors in yeast

1987 • 79 citations

Structural and functional analyses of Saccharomyces cerevisiae wild-type and mutant RNA1 genes.

1989 • 65 citations

PRP4: a Protein of the Yeast U4/U6 Small Nuclear Ribonucleoprotein Particle

1989 • 62 citations

Split tRNA genes and their products: A paradigm for the study of cell function and evolution

1989 • 57 citations

N2,N2-dimethylguanosine-specific tRNA methyltransferase contains both nuclear and mitochondrial targeting signals in Saccharomyces cerevisiae.

1989 • 57 citations

Characterization of an essential Saccharomyces cerevisiae gene related to RNA processing: cloning of RNA1 and generation of a new allele with a novel phenotype.

1985 • 48 citations

RNA11 Protein is Associated with the Yeast Spliceosome and is Localized in the Periphery of the Cell Nucleus

1988 • 45 citations

Identification and nuclear localization of yeast pre-messenger RNA processing components: RNA2 and RNA3 proteins.

1986 • 33 citations

Structural and Functional Analyses of Saccharomyces cerevisiae Wild-Type and Mutant RNA1 Genes

1989 • 29 citations

A suppressor of temperature-sensitive rna mutations that affect mRNA metabolism in Saccharomyces cerevisiae.

1982 • 23 citations

Yeast mutation thought to arrest mRNA transport markedly increases the length of the 3′ poly(A) on polyadenylated RNA

1989 • 23 citations

Characterization of an Essential Saccharomyces cerevisiae Gene Related to RNA Processing: Cloning of RNA1 and Generation of a New Allele with a Novel Phenotype

1985 • 16 citations

A Suppressor of Temperature-Sensitive rna Mutations that Affect mRNA Metabolism in Saccharomyces cerevisiae

1982 • 8 citations