rarmutations which increase artificial chromosome stability inSaccharomyces cerevisiaeidentify transcription and recombination proteins

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

Methods in yeast genetics

1979 • 7,824 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

A cellular DNA-binding protein that activates eukaryotic transcription and DNA replication

1987 • 1,050 citations

The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain

1989 • 781 citations

Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements

1987 • 637 citations

ANIMAL VIRUS DNA REPLICATION

1989 • 520 citations

Two DNA-binding factors recognize specific sequences at silencers, upstream activating sequences, autonomously replicating sequences, and telomeres in Saccharomyces cerevisiae.

1988 • 511 citations

Mitotic stability of yeast chromosomes: A colony color assay that measures nondisjunction and chromosome loss

1985 • 486 citations

MUTANTS OF S. CEREVISIAE DEFECTIVE IN THE MAINTENANCE OF MINICHROMOSOMES

1984 • 419 citations

Binding and unwinding—How T antigen engages the SV40 origin of DNA replication

1990 • 404 citations

A third essential DNA polymerase in S. cerevisiae

1990 • 360 citations

The current status and portability of our sequence handling software

1986 • 357 citations

ENZYMES OF GENERAL RECOMBINATION

1987 • 333 citations

Genetic analysis of the mitotic transmission of minichromosomes

1985 • 310 citations

Centromeric DNA from Saccharomyces cerevisiae

1982 • 292 citations

[7] Random cloning and sequencing by the M13/dideoxynucleotide chain termination method

1987 • 292 citations

Connections Between Transcriptional Activators, Silencers, and Telomeres as Revealed by Functional Analysis of a Yeast DNA-Binding Protein

1988 • 284 citations

SPXX, a frequent sequence motif in gene regulatory proteins

1989 • 276 citations

Yeast chromosome replication and segregation

1988 • 250 citations

Purification of a yeast protein that binds to origins of DNA replication and a transcriptional silencer.

1988 • 234 citations

Structural requirements for the function of a yeast chromosomal replicator

1984 • 231 citations

Bent DNA at a yeast autonomously replicating sequence

1986 • 217 citations

A cdc2-like protein is involved in the initiation of DNA replication in Xenopus egg extracts

1990 • 209 citations

Transcription Factor OTF-1 Is Functionally Identical to the DNA Replication Factor NF-III

1988 • 194 citations

Transcriptional activator nuclear factor I stimulates the replication of SV40 minichromosomes in vivo and in vitro

1989 • 182 citations

Similarity Between the Transcriptional Silencer Binding Proteins ABF1 and RAP1

1989 • 180 citations

Roles of two DNA-binding factors in replication, segregation and transcriptional repression mediated by a yeast silencer.

1988 • 174 citations

Two DNA-Binding Factors Recognize Specific Sequences at Silencers, Upstream Activating Sequences, Autonomously Replicating Sequences, and Telomeres in Saccharomyces cerevisiae

1988 • 170 citations

The yeast transcription activator PRTF, a homolog of the mammalian serum response factor, is encoded by the MCM1 gene.

1989 • 160 citations

GAL11P: A yeast mutation that potentiates the effect of weak GAL4-derived activators

1990 • 149 citations

The DNA binding domain (POU domain) of transcription factor oct-1 suffices for stimulation of DNA replication.

1990 • 149 citations

Transcription interferes with elements important for chromosome maintenance in Saccharomyces cerevisiae.

1988 • 148 citations

RNase H confers specificity in the dnaA-dependent initiation of replication at the unique origin of the Escherichia coli chromosome in vivo and in vitro.

1984 • 146 citations

A yeast ARS-binding protein activates transcription synergistically in combination with other weak activating factors.

1990 • 146 citations

GAL11 protein, an auxiliary transcription activator for genes encoding galactose-metabolizing enzymes in Saccharomyces cerevisiae.

1988 • 145 citations

New beginnings in studies of eukaryotic DNA replication origins

1989 • 139 citations

The phenotype of the minichromosome maintenance mutant mcm3 is characteristic of mutants defective in DNA replication.

1990 • 138 citations

THE ESSENTIAL ROLE OF RECOMBINATION IN PHAGE T4 GROWTH

1987 • 124 citations

kem mutations affect nuclear fusion in Saccharomyces cerevisiae.

1990 • 117 citations

Partial purification and characterization of a recombinase from human cells

1986 • 116 citations

Amino acid replacements resulting from super-suppression of nonsense mutants of iso-1-cytochrome c from yeast

1971 • 109 citations

The Saccharomyces cerevisiae SPT13/GAL11 gene has both positive and negative regulatory roles in transcription.

1989 • 101 citations

A Tn 10-lacZ-kanR-URA3 Gene Fusion Transposon for Insertion Mutagenesis and Fusion Analysis of Yeast and Bacterial Genes

1987 • 100 citations

Purification and characterization of proteins that bind to yeast ARSs.

1988 • 94 citations

Sequence, expression and mutational analysis of BAF1, a transcriptional activator and ARS1-binding protein of the yeast Saccharomyces cerevisiae.

1989 • 93 citations

Yeast Gal11 protein mediates the transcriptional activation signal of two different transacting factors, Gal4 and general regulatory factor I/repressor/activator site binding protein 1/translation upstream factor.

1990 • 88 citations

Effect of ARS1 mutations on chromosome stability in Saccharomyces cerevisiae.

1985 • 80 citations

Isolation of Saccharomyces cerevisiae mutants constitutive for invertase synthesis

1986 • 80 citations

PLEIOTROPIC MUTATIONS AT THE TUP1 LOCUS THAT AFFECT THE EXPRESSION OF MATING-TYPE-DEPENDENT FUNCTIONS IN SACCHAROMYCES CEREVISIAE

1980 • 76 citations

Isolation and DNA-binding characteristics of a protein involved in transcription activation of two divergently transcribed, essential yeast genes.

1989 • 72 citations

A mutant that affects the function of autonomously replicating sequences in yeast

1986 • 65 citations

Sequence of the T4 recombination gene,uvsX, and its comparison with that of therecAgene ofEscherichia coil

1985 • 65 citations

DNA strand transfer protein beta from yeast mitotic cells differs from strand transfer protein alpha from meiotic cells.

1990 • 64 citations

Transcription Interferes with Elements Important for Chromosome Maintenance in Saccharomyces cerevisiae

1988 • 63 citations

Analysis of sequences conferring autonomous replication in baker's yeast.

1983 • 56 citations

Drosophila melanogaster Strand Transferase

1989 • 56 citations

Reversion of autonomously replicating sequence mutations in Saccharomyces cerevisiae: creation of a eucaryotic replication origin within procaryotic vector DNA.

1990 • 55 citations

The enzymes of the galactose cluster in Saccharomyces cerevisiae. II. Purification and characterization of uridine diphosphoglucose 4-epimerase.

1980 • 52 citations

The OBF1 protein and its DNA-binding site are important for the function of an autonomously replicating sequence in Saccharomyces cerevisiae.

1989 • 52 citations

A yeast mutation that stabilizes a plasmid bearing a mutated ARS1 element.

1989 • 48 citations

Genetic inactivation of topoisomerase I suppresses a defect in initiation of chromosome replication in Escherichia coli

1984 • 48 citations

The Phenotype of the Minichromosome Maintenance Mutant mcm3 Is Characteristic of Mutants Defective in DNA Replication

1990 • 47 citations

Yeast as a model system for understanding the control of DNA replication in eukaryotes

1990 • 46 citations

GAL11 Protein, an Auxiliary Transcription Activator for Genes Encoding Galactose-Metabolizing Enzymes in Saccharomyces cerevisiae

1988 • 43 citations

Topoisomerase I confers specificity in enzymatic replication of the Escherichia coli chromosomal origin.

1984 • 43 citations

A recombinase from Drosophila melanogaster embryos.

1988 • 40 citations

A Yeast ARS-Binding Protein Activates Transcription Synergistically in Combination with Other Weak Activating Factors

1990 • 38 citations

The Saccharomyces cerevisiae SPT13/GAL11 Gene Has Both Positive and Negative Regulatory Roles in Transcription

1989 • 34 citations

Effect of ARS1 Mutations on Chromosome Stability in Saccharomyces cerevisiae

1985 • 32 citations

Purification and characterization of OBF1: a Saccharomyces cerevisiae protein that binds to autonomously replicating sequences.

1989 • 32 citations

Anti-OTF-1 antibodies inhibit NFIII stimulation ofin vitroadenovirus DNA replication

1989 • 31 citations

Mutations that increase the mitotic stability of minichromosomes in yeast: Characterization of RAR1

1987 • 29 citations

Nucleotide sequence of the REC1 gene ofUstilago maydis

1989 • 21 citations

The OBF1 Protein and Its DNA-Binding Site Are Important for the Function of an Autonomously Replicating Sequence in Saccharomyces cerevisiae†

1989 • 20 citations

Reversion of Autonomously Replicating Sequence Mutations in Saccharomyces cerevisiae: Creation of a Eucaryotic Replication Origin within Procaryotic Vector DNA

1990 • 15 citations

A Yeast Mutation That Stabilizes a Plasmid Bearing a Mutated ARS1 Element

1989 • 14 citations

Purification and Characterization of OBF1: a Saccharomyces cerevisiae Protein That Binds to Autonomously Replicating Sequences†

1989 • 13 citations

Analysis of expression of hybrid yeast genes containing ARS elements

1989 • 10 citations