A Possible Mechanism for Hyperthermic Radiosensitization Mediated through Hyperthermic Lability of Ku Subunits in DNA-Dependent Protein Kinase

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Radiobiology for the Radiologist.

1974 • 3,582 citations

Radiobiology for the Radiologist

1995 • 1,349 citations

The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen

1993 • 1,219 citations

Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation

1995 • 862 citations

DNA-dependent protein kinase catalytic subunit: A relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

1995 • 742 citations

Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination

1994 • 637 citations

DNA-Dependent Kinase (p350) as a Candidate Gene for the Murine SCID Defect

1995 • 610 citations

Absence of p350 Subunit of DNA-Activated Protein Kinase from a Radiosensitive Human Cell Line

1995 • 530 citations

scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair.

1991 • 509 citations

Mechanism of interaction between Ku protein and DNA.

1986 • 485 citations

Human DNA-Activated Protein Kinase Phosphorylates Serines 15 and 37 in the Amino-Terminal Transactivation Domain of Human p53

1992 • 473 citations

Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen.

1990 • 415 citations

Restoration of X-ray Resistance and V(D)J Recombination in Mutant Cells by Ku cDNA

1994 • 351 citations

DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK

1995 • 344 citations

Characterization of the DNA-binding protein antigen Ku recognized by autoantibodies from patients with rheumatic disorders.

1986 • 333 citations

Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells.

1995 • 286 citations

A DNA-activated protein kinase from HeLa cell nuclei.

1990 • 285 citations

Purification and characterization of a template-associated protein kinase that phosphorylates RNA polymerase II

1993 • 184 citations

Hyperthermic Effects on DNA Repair Mechanisms

1977 • 168 citations

The DNA-activated protein kinase is required for the phosphorylation of replication protein A during simian virus 40 DNA replication.

1994 • 163 citations

Effect of Hyperthermia on CHO DNA Polymerases α and β

1982 • 139 citations

Modification and Inhibition of Repair of Potentially Lethal X-Ray Damage by Hyperthermia

1976 • 133 citations

Phosphorylation of the p34 subunit of human single-stranded-DNA-binding protein in cyclin A-activated G1 extracts is catalyzed by cdk-cyclin A complex and DNA-dependent protein kinase.

1994 • 110 citations

Radiosensitivity Throughout the Cell Cycle and Repair of Potentially Lethal Damage and DNA Double-strand Breaks in an X-ray-sensitive CHO Mutant

1990 • 72 citations

DNA‐activated protein kinase in Raji Burkitt's lymphoma cells

1992 • 49 citations

Response of X-Ray-Sensitive CHO Mutant Cells to g Radiation: I. Effects of Low Dose Rates and the Process of Repair of Potentially Lethal Damage in G 1 Phase

1989 • 44 citations

Recovery of sublethal radiation damage and its inhibition by hyperthermia in normal and transformed mouse cells

1992 • 28 citations

Cultured Cells from a Severe Combined Immunodeficient Mouse Have a Slower Than Normal Rate of Repair of Potentially Lethal Damage Sensitive to Hypertonic Treatment

1995 • 14 citations