Restoration of X-ray Resistance and V(D)J Recombination in Mutant Cells by Ku cDNA

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

SRα Promoter: an Efficient and Versatile Mammalian cDNA Expression System Composed of the Simian Virus 40 Early Promoter and the R-U5 Segment of Human T-Cell Leukemia Virus Type 1 Long Terminal Repeat

1988 • 1,351 citations

Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination

1994 • 637 citations

Mechanism of interaction between Ku protein and DNA.

1986 • 485 citations

Impairment of V(D)J Recombination in Double-Strand Break Repair Mutants

1993 • 457 citations

Characterization of a high molecular weight acidic nuclear protein recognized by autoantibodies in sera from patients with polymyositis-scleroderma overlap.

1981 • 430 citations

Binding of Ku protein to DNA. Measurement of affinity for ends and demonstration of binding to nicks.

1993 • 311 citations

EBP-80, a transcription factor closely resembling the human autoantigen Ku, recognizes single- to double-strand transitions in DNA

1993 • 247 citations

Absence of a Ku-like DNA end binding activity in the xrs double-strand DNA repair-deficient mutant.

1994 • 238 citations

DNA damage and the DNA-activated protein kinase

1993 • 237 citations

Involvement of the Ku autoantigen in the cellular response to DNA double-strand breaks.

1994 • 215 citations

Molecular Cloning of cDNA Encoding the p70 (Ku) Lupus Autoantigen

1989 • 212 citations

V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair.

1993 • 193 citations

Mutant rodent cell lines sensitive to ultraviolet light, ionizing radiation and cross-linking agents: a comprehensive survey of genetic and biochemical characteristics

1993 • 193 citations

A DNA end-binding factor involved in double-strand break repair and V(D)J recombination.

1994 • 164 citations

Isolation and characterization of cDNA encoding the 80-kDa subunit protein of the human autoantigen Ku (p70/p80) recognized by autoantibodies from patients with scleroderma-polymyositis overlap syndrome.

1990 • 152 citations

DNA-dependent protein kinase is activated by nicks and larger single-stranded gaps

1994 • 139 citations

cDNA-derived Amino Acid Sequence of the 86-kDa Subunit of the Ku Antigen

1989 • 125 citations

Ku polypeptides synthesized in vitro assemble into complexes which recognize ends of double-stranded DNA.

1992 • 98 citations

Chromosomal location and expression of the genes coding for Ku p70 and p80 in human cell lines and normal tissues

1994 • 90 citations

Gene recombination in X-ray-sensitive hamster cells.

1987 • 58 citations

Subchromosomal localization of a gene (XRCC5) involved in double strand break repair to the region 2q34-36

1993 • 45 citations

Homologous recombination in a Chinese hamster X-ray-sensitive mutant

1986 • 36 citations

Activities Involved in V(D)J Recombination

1992 • 29 citations

Regional Assignment of a Human DNA Repair Gene (XRCC5) to 2q35 by X-Ray Hybrid Mapping

1994 • 24 citations

Genotoxicity assessment of waste products of aluminum plasma etching with the SOS chromotest

1993 • 18 citations