Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen.

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

PROTEIN SERINE/THREONINE KINASES

1987 • 1,457 citations

The Genome of Simian Virus 40

1978 • 948 citations

p53: oncogene or anti-oncogene?

1990 • 812 citations

Processing of Adenovirus 2-Induced Proteins

1973 • 762 citations

Cellular targets for transformation by the adenovirus E1A proteins

1989 • 747 citations

Differential transcriptional activation by Oct-1 and Oct-2: Interdependent activation domains induce Oct-2 phosphorylation

1990 • 696 citations

GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase

1990 • 677 citations

Mechanism of interaction between Ku protein and DNA.

1986 • 485 citations

Driving the cell cycle: M phase kinase, its partners, and substrates

1990 • 404 citations

Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2.

1990 • 353 citations

Characterization of the DNA-binding protein antigen Ku recognized by autoantibodies from patients with rheumatic disorders.

1986 • 333 citations

Activation of casein kinase II in response to insulin and to epidermal growth factor.

1987 • 299 citations

Improvement and simplification of low‐background silver staining of proteins by using sodium dithionite

1988 • 297 citations

A DNA-activated protein kinase from HeLa cell nuclei.

1990 • 285 citations

Structural requirements of double-stranded RNA for the activation of 2‘,5‘-oligo(A) polymerase and protein kinase of interferon-treated HeLa cells.

1979 • 263 citations

Phosphorylation of large tumour antigen by cdc2 stimulates SV40 DNA replication

1989 • 242 citations

Molecular Cloning of cDNA Encoding the p70 (Ku) Lupus Autoantigen

1989 • 212 citations

Simian Virus 40 Large T Antigen Is Phosphorylated at Multiple Sites Clustered in Two Separate Regions

1982 • 193 citations

Two human 90-kDa heat shock proteins are phosphorylated in vivo at conserved serines that are phosphorylated in vitro by casein kinase II

1989 • 190 citations

The replication functions of SV40 T antigen are regulated by phosphorylation

1990 • 180 citations

The Human Double-stranded DNA-activated Protein Kinase Phosphorylates the 90-kDa Heat-shock Protein, hsp90α at Two NH2-terminal Threonine Residues

1989 • 177 citations

Serum-stimulated cell growth causes oscillations in casein kinase II activity

1989 • 171 citations

Specific amino acid substitutions in bacterioopsin: Replacement of a restriction fragment in the structural gene by synthetic DNA fragments containing altered codons

1984 • 158 citations

Isolation and characterization of cDNA encoding the 80-kDa subunit protein of the human autoantigen Ku (p70/p80) recognized by autoantibodies from patients with scleroderma-polymyositis overlap syndrome.

1990 • 152 citations

Expression of simian virus 40 T antigen in insect cells using a baculovirus expression vector

1988 • 152 citations

Double-stranded DNA induces the phosphorylation of several proteins including the 90 000 mol. wt. heat-shock protein in animal cell extracts.

1985 • 143 citations

The p53 nuclear localisation signal is structurally linked to a p34cdc2 kinase motif.

1990 • 135 citations

cDNA-derived Amino Acid Sequence of the 86-kDa Subunit of the Ku Antigen

1989 • 125 citations

Mutations in the phosphorylation sites of simian virus 40 (SV40) T antigen alter its origin DNA-binding specificity for sites I or II and affect SV40 DNA replication activity

1988 • 125 citations

Inhibitory effect of 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole on a protein kinase.

1984 • 111 citations

A DNA-Activated Protein Kinase from HeLa Cell Nuclei

1990 • 109 citations

Expression and complex formation of simian virus 40 large T antigen and mouse p53 in insect cells

1988 • 107 citations

The amino acid sequence of murine p53 determined from a c-DNA clone

1984 • 104 citations

In Vitro phosphorylation of SV40 large T antigen

1988 • 103 citations

Selective inhibition of a cyclic nucleotide independent protein kinase (G type casein kinase) by quercetin and related polyphenols

1982 • 102 citations

Cloning and expression analysis of full length mouse cDNA sequences encoding the transformation associated protein p53

1984 • 85 citations

Cloning and Characterization of a cDNA That Encodes a 70-kDa Novel Human Thyroid Autoantigen

1989 • 85 citations

Identification of proteins and protein domains that contact DNA within adenovirus nucleoprotein cores by ultraviolet light crosslinking of oligonucleotides 32P-labelled in vivo

1986 • 77 citations

Phosphorylation of p53 in normal and simian virus 40-transformed NIH 3T3 cells.

1988 • 77 citations

Mapping of phosphomonoester and apparent phosphodiester bonds of the oncogene product p53 from simian virus 40-transformed 3T3 cells.

1986 • 76 citations

A 10S particle released from deoxyribonuclease-sensitive regions of HeLa cell nuclei contains the 86-kilodalton-70-kilodalton protein complex

1986 • 68 citations

Protein Serine Threonine Kinases

1987 • 63 citations

Control of Enzyme Activity

1983 • 58 citations

p53 — Oncogene or Anti-Oncogene?

1990 • 32 citations

Phosphorylation of p53 in Normal and Simian Virus 40-Transformed NIH 3T3 Cells

1988 • 30 citations

DNA-stimulated protein phosphorylation in HeLa whole cell and nuclear extracts

1988 • 24 citations