Direct visualization of distinct T cell epitopes derived from a melanoma tumor-associated antigen by using human recombinant antibodies with MHC- restricted T cell receptor-like specificity

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1996 • 3,611 citations

Quantitation of HIV-1-Specific Cytotoxic T Lymphocytes and Plasma Load of Viral RNA

1998 • 1,426 citations

Progress in human tumour immunology and immunotherapy

2001 • 1,327 citations

Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients

1999 • 1,131 citations

A new gene coding for a differentiation antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas.

1994 • 934 citations

Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection.

1994 • 921 citations

Human tumor antigens recognized by T lymphocytes.

1996 • 860 citations

Identification of a Peptide Recognized by Five Melanoma-Specific Human Cytotoxic T Cell Lines

1994 • 841 citations

A listing of human tumor antigens recognized by T cells

2001 • 708 citations

Localization, Quantitation, and In Situ Detection of Specific Peptide–MHC Class I Complexes Using a Monoclonal Antibody

1997 • 679 citations

Regression of human metastatic renal cell carcinoma after vaccination with tumor cell–dendritic cell hybrids

2000 • 652 citations

Identification of human cancers deficient in antigen processing.

1993 • 625 citations

Melanocyte lineage-specific antigen gp100 is recognized by melanoma-derived tumor-infiltrating lymphocytes.

1994 • 584 citations

Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression.

1995 • 552 citations

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A Large Non-immunized Human Fab Fragment Phage Library That Permits Rapid Isolation and Kinetic Analysis of High Affinity Antibodies

1999 • 527 citations

Antigen-processing machinery breakdown and tumor growth

2000 • 444 citations

Improving antibody affinity by mimicking somatic hypermutation in vitro

1999 • 252 citations

Visualization of Myelin Basic Protein (Mbp) T Cell Epitopes in Multiple Sclerosis Lesions Using a Monoclonal Antibody Specific for the Human Histocompatibility Leukocyte Antigen (Hla)-Dr2–Mbp 85–99 Complex

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A novel MHC class II epitope expressed in thymic medulla but not cortex

1989 • 175 citations

Melanoma cells and normal melanocytes share antigens recognized by HLA-A2-restricted cytotoxic T cell clones from melanoma patients.

1993 • 173 citations

Characterization and Quantitation of Peptide–MHC Complexes Produced from Hen Egg Lysozyme Using a Monoclonal Antibody

1997 • 169 citations

Production, specificity, and functionality of monoclonal antibodies to specific peptide–major histocompatibility complex class II complexes formed by processing of exogenous protein

1997 • 150 citations

A recombinant antibody with the antigen-specific, major histocompatibility complex-restricted specificity of T cells.

1996 • 131 citations

Antigen-unspecific B Cells and Lymphoid Dendritic Cells Both Show Extensive Surface Expression of Processed Antigen–Major Histocompatibility Complex Class II Complexes after Soluble Protein Exposure In Vivo or In Vitro

1997 • 128 citations

Direct selection of a human antibody fragment directed against the tumor T-cell epitope HLA-A1–MAGE-A1 from a nonimmunized phage-Fab library

2000 • 119 citations

Isolation and characterization of human recombinant antibodies endowed with the antigen-specific, major histocompatibility complex-restricted specificity of T cells directed toward the widely expressed tumor T-cell epitopes of the telomerase catalytic subunit.

2002 • 97 citations

Direct delivery of exogenous MHC class I molecule-binding oligopeptides to the endoplasmic reticulum of viable cells

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Design and evaluation of antigen-specific vaccination strategies against cancer

2000 • 94 citations

Immunomodulation of experimental allergic encephalomyelitis by antibodies to the antigen–Ia complex

1991 • 92 citations

Critical Role for CD8 in Binding of MHC Tetramers to TCR: CD8 Antibodies Block Specific Binding of Human Tumor- Specific MHC-Peptide Tetramers to TCR

2001 • 86 citations

Correctly Folded T-cell Receptor Fragments in the Periplasm of Escherichia coli

1994 • 76 citations

Targeted therapy of cancer with recombinant immunotoxins

1997 • 75 citations

TCR-Like Human Antibodies Expressed on Human CTLs Mediate Antibody Affinity-Dependent Cytolytic Activity

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A phage display selected Fab fragment with MHC class I-restricted specificity for MAGE-A1 allows for retargeting of primary human T lymphocytes

2001 • 74 citations

Targeted Cytokines for Cancer Immunotherapy

2000 • 62 citations

The use of dendritic cells for cancer vaccination.

1999 • 58 citations

Recombinant human single-chain MHC-peptide complexes made fromE. coli byin vitro refolding: functional single-chain MHC-peptide complexes and tetramers with tumor associated antigens

2000 • 54 citations

Bi-specific antibody therapy for the treatment of cancer.

2001 • 50 citations

T-cell clones from melanoma patients immunized against an anchor-modified gp100 peptide display discordant effector phenotypes.

2000 • 46 citations

Peptide-specific killing of antigen-presenting cells by a recombinant antibody–toxin fusion protein targeted to major histocompatibility complex/peptide class I complexes with T cell receptor-like specificity

1997 • 39 citations

Generation of human-melanoma-specific T lymphocyte clones defining novel cytolytic targets with panels of newly established melanoma cell lines

1995 • 35 citations

Recognition of Melanoma-Derived Antigens by CTL: Possible Mechanisms Involved in Down-Regulating Anti-Tumor T-Cell Reactivity

1998 • 33 citations